Anb

Biodesign Directory Profile

Contact Information

(480)965-2805

Joshua LaBaer, MD, PhD

Virginia G. Piper Chair in Personalized Medicine

Director

The Biodesign Institute, Personalized Diagnostics

Bio

Visit the LaBaer Lab Web Site

Joshua LaBaer is one of the nation’s foremost investigators in the rapidly expanding field of personalized medicine. His efforts involve the discovery and validation of biomarkers — unique molecular fingerprints of disease — which can provide early warning for those at risk of major illnesses, including cancer and diabetes.

The Virginia G. Piper Center for Personalized Diagnostics (VGPCPD) has a highly multidisciplinary staff of molecular biologists, cell biologists, biochemists, software engineers, database specialists, bioinformaticists, biostatisticians, and automation engineers with individuals ranging from Ph.D. and M.D. degrees to graduate students to technical support individuals.  An organizing principle of VGPCPD is the application of open reading frame clones to the high throughput (HT) study of protein function. 

Dr. LaBaer was an early initiator and leader of the effort to build fully sequence-verified recombination-based clone sets for human genes and other model organisms now managed in an automated repository with more than 250,000 samples, which are openly shared with the scientific community.  His laboratory has developed a number of methods to employ these clones, including HT protein expression and purification, and HT screens of ectopic protein expression in mammalian cells for relevant phenotypes. 

In addition, his group invented a novel protein microarray technology, Nucleic Acid Programmable Protein Array, which has been used widely for biomedical research, including the recent discovery of a panel of 28 autoantibody biomarkers that may aid the early diagnosis of breast cancer.

Formerly founder and director of the Harvard Institute of Proteomics, LaBaer was recruited to ASU’s Biodesign Institute as the first Piper Chair in Personalized Medicine in 2009.

Dr. LaBaer completed both his medical internship and residency at the Brigham and Women’s Hospital and a clinical fellowship in oncology at the Dana-Farber Cancer Institute, both in Boston. He is a board certified physician in internal medicine and medical oncology and was an instructor and clinical fellow in medicine at Harvard Medical School. He has contributed more than 120 original research publications, reviews and chapters.

LaBaer is an associate editor of the Journal of Proteome Research and a member of the editorial boards of Analytical Biochemistry, Current Opinion in Biotechnology, Cancer Biomarkers, Molecular Biosystems, and Clinical Proteomics. He is a member of the National Cancer Institute’s Board of Scientific Advisors and serves as chair of the National Cancer Institute’s Early Detection Research Network Executive Committee and Co-Chair of its Steering Committee.  He is treasurer and president-elect of the U.S. Human Proteome Organization.  He also serves on a number of government and industry scientific advisory boards.

LaBaer earned his medical degree and a doctorate in biochemistry and biophysics, from the University of California, San Francisco. 

Education:

1981 - B.S. University of California, Berkeley, California
1989 - Ph.D. University of California School of Medicine, San Francisco, California (Biochemistry and Biophysics)
1990 - M.D. University of California School of Medicine

Awards and Honors:

    1978 Edward Frank Kraft Prize for Outstanding Academic Achievement, University of California
    1977-1981 Regents Scholar, University of California
    1981 Phi Beta Kappa
    1981 Citation for Outstanding Student Research, UC Berkeley
    1981 University Medal for Most Distinguished Graduating Senior, UC Berkeley
    1981 Graduation with Highest Honors, UC Berkeley
    1985 Dean’s Prize for Student Research
    1986-1987 Chancellor’s Fellowship
    1989 Alpha Omega Alpha
    2001-04 Arthur and Rochelle Belfer Foundation Awardee, Breast Cancer Research Foundation
    2005- Breast Cancer Research Foundation
    2007 Kavli Frontiers of Science Symposium Recipient
    2009 The Otto Herz Memorial Lectureship in Cancer Research
    2009 The Virginia G. Piper Chair of Personalized Medicine
    2011 Health Care Hero [researcher/innovator]; Phoenix Business Journal

Major Research Interests:

    1. Finding drug and vaccine targets for biodefense pathogens
    2. Disease biomarker discovery
    3. Estrogen resistance in breast cancer
    4. Protein microarray technology and protein interaction mapping
    5. DNA-damage checkpoint regulation

Publications, Original Articles, Reviews, Chapters, and Editorials

Defranco, A. L.; LaBaer, J.; Fahey, K. A.; Tsien, R. Y., Crosslinkage Of Membrane IGM Causes An Increase In Cytoplasmic Calcium Via Phosphoinositide Hydrolysis. Federation Proceedings 1985, 44, (4), 1297-1297.

LaBaer, J.; Tsien, R.; Defranco, A., Anti-Receptor Antibodies Stimulate A Rise In Intracellular Calcium In Lymphocytes-B. Clinical Research 1985, 33, (2), A381-A381.

LaBaer, J.; Tsien, R. Y.; Fahey, K. A.; Defranco, A. L., Stimulation Of The Antigen Receptor On Wehi-231 B-Lymphoma Cells Results In A Voltage-Independent Increase In Cytoplasmic Calcium. Journal of Immunology 1986, 137, (6), 1836-1844.

LaBaer J.  Rapid sequencing of miniprep DNA using Sequenase and end-labeled sequencing primer.  US Biochemicals, 1989 (Comments) 15: 19–20.

Garabedian MJ, LaBaer J, Liu W-H, Thomas J.  “Analysis of protein – DNA Interactions.”  Gene Transcription - A Practical Approach, Oxford: Oxford University Press,1993: 243–295.  ISBN 0199632928.

Enders, G.; Harlow, E.; LaBaer, J.; Meyerson, M.; Tsai, L. H.; Vandenheuvel, S., Cyclin-Dependent Kinases. Faseb Journal 1994, 8, (7), A1262-A1262.

LaBaer, J.; Yamamoto, K. R., Analysis Of The DNA-Binding Affinity, Sequence Specificity and Context Dependence of the Glucocorticoid Receptor Zinc-Finger Region. Journal of Molecular Biology 1994, 239, (5), 664-688.

Hiyama, H.; Iavarone, A.; LaBaer, J.; Reeves, S. A., Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression. Oncogene 1997, 14, (21), 2533-2542.

Hu, G.; Zhang, S.; Vidal, M.; LaBaer, J.; Xu, T.; Fearon, E. R., Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway. Genes & Development 1997, 11, (20), 2701-2714.

LaBaer, J.; Garrett, M. D.; Stevenson, L. F.; Slingerland, J. M.; Sandhu, C.; Chou, H. S.; Fattaey, A.; Harlow, E., New functional activities for the p21 family of CDK inhibitors. Genes & Development 1997, 11, (7), 847-862.

Brizuela, L.; Braun, P.; LaBaer, J., FLEXGene repository: from sequenced genomes to gene repositories for high-throughput functional biology and proteomics. Molecular and Biochemical Parasitology 2001, 118, (2), 155-165.

Marsischky, G.; Richardson, A.; Hogel, C.; Weger, J.; Brizuela, L.; LaBaer, J.; Harlow, E.; Kolodner, R., Creation of the yeast FLEX (Full-Length expression) library. Yeast 2001, 18, S111-S111.

Braun, P.; Hu, Y. H.; Shen, B. H.; Halleck, A.; Koundinya, M.; Harlow, E.; LaBaer, J., Proteome-scale purification of human proteins from bacteria. Proceedings of the National Academy of Sciences of the United States of America 2002, 99, (5), 2654-2659.

Brizuela, L.; Richardson, A.; Marsischky, G.; LaBaer, J., The FLEXGene repository: Exploiting the fruits of the genome projects by creating a needed resource to face the challenges of the post-genomic era. Archives of Medical Research 2002, 33, (4), 318-324.

LaBaer, J., Genomics, proteomics, and the new paradigm in biomedical research. Genetics in Medicine 2002, 4, (6), 2S-9S.

Braun, P.; LaBaer, J., High throughput protein production for functional proteomics. Trends in Biotechnology 2003, 21, (9), 383-388.

Hu, Y. H.; Hines, L. M.; Weng, H. F.; Zuo, D. M.; Rivera, M.; Richardson, A.; LaBaer, J., Analysis of genomic and proteomic data using advanced literature mining. Journal of Proteome Research 2003, 2, (4), 405-412.

LaBaer, J., Harnessing the proteome. Biopolymers 2003, 71, (3), L8.

LaBaer, J., Mining the literature and large datasets. Nature Biotechnology 2003, 21, (9), 976-977.

Aguiar, J. C.; LaBaer, J.; Blair, P. L.; Shamailova, V. Y.; Koundinya, M.; Russell, J. A.; Huang, F. Y.; Mar, W.; Anthony, R. M.; Witney, A.; Caruana, S. R.; Brizuela, L.; Sacci, J. B.; Hoffman, S. L.; Carucci, D. J., High-throughput generation of P. falciparum functional molecules by recombinational cloning. Genome Research 2004, 14, (10B), 2076-2082.

Braun, P.; LaBaer, J., High throughput protein production for functional proteomics. Drug Discovery Today 2004, 9, (2), S1-S7.

Hu, Y. H.; LaBaer, J., Tracking gene-disease relationships for high-throughput functional studies. Surgery 2004, 136, (3), 504-510. ISSN 0039-6060.

LaBaer, J., Harnessing the proteome. Abstracts of Papers of the American Chemical Society 2004, 228, 211-ANYL.

LaBaer, J.; Qiu, Q. Q.; Anumanthan, A.; Mar, W.; Zuo, D. M.; Murthy, T. V. S.; Taycher, H.; Halleck, A.; Hainsworth, E.; Lory, S.; Brizuela, L., The Pseudomonas aerugonisa PAO1 gene collection. Genome Research 2004, 14, (10B), 2190-2200.

Marsischky, G.; LaBaer, J., Many paths to many clones: A comparative look at high-throughput cloning methods. Genome Research 2004, 14, (10B), 2020-2028.

Murthy, T. V. S.; Wu, W. L.; Qiu, Q. Q.; Shi, Z. W.; LaBaer, J.; Brizuela, L., Bacterial cell-free system for high-throughput protein expression and a comparative analysis of Escherichia coli cell-free and whole cell expression systems. Protein Expression and Purification 2004, 36, (2), 217-225.

Pearlberg, J.; LaBaer, J., Protein expression clone repositories for functional proteomics. Current Opinion in Chemical Biology 2004, 8, (1), 98-102.

Ramachandran, N.; Hainsworth, E.; Bhullar, B.; Eisenstein, S.; Rosen, B.; Lau, A. Y.; Walter, J. C.; LaBaer, J., Self-assembling protein microarrays. Science 2004, 305, (5680), 86-90.

Seton-Rogers, S. E.; Lu, Y.; Hines, L. M.; Koundinya, M.; LaBaer, J.; Muthuswamy, S. K.; Brugge, J. S., Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 2004, 101, (5), 1257-1262.

Nakamura K, Aebersold R, Bairoch A, Dunn M, Celis J, Hanash S, Hochstrasser D, Humphrey-Smith I, James P, Klose J, LaBaer J, Langen H, Mann M, Parekh R, Patterson S, Pearce C, Poepstorff P, Simpson RJ, Tomlinson I, Tsugita A, Yates J. From genome to proteome--aim of human proteomics, Seikagaku 2004 Oct;76(10):1271-4.

Anderson, K. S.; LaBaer, J., The sentinel within: Exploiting the immune system for cancer biomarkers. Journal of Proteome Research 2005, 4, (4), 1123-1133.

Chang, C. Y.; LaBaer, J., DNA polymorphism detector: an automated tool that searches for allelic matches in public databases for discrepancies found in clone or cDNA sequences. Bioinformatics 2005, 21, (9), 2133-2135.

Collins, N. L.; Reginato, M. J.; Paulus, J. K.; Sgroi, D. C.; LaBaer, J.; Brugge, J. S., G(1)/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression. Molecular and Cellular Biology 2005, 25, (12), 5282-5291.

Fan, M.; Tsai, J.; Chen, B. J.; Fan, K.; LaBaer, J., A central repository for published plasmids. Science 2005, 307, (5717), 1877-1877.

Komaroff, A. L.; LaBaer, J., Health for life. Genomic medicine: the science speeds up. Newsweek 2005, 146, (24), 57.

LaBaer, J., So, you want to look for biomarkers - (Introduction to the special biornarkers issue). Journal of Proteome Research 2005, 4, (4), 1053-1059.

LaBaer, J.; Carr, S. A., The marriage of proteomics and biomarkers. Journal of Proteome Research 2005, 4, (4), 1043-1043.

LaBaer, J.; Ramachandran, N., Protein microarrays as tools for functional proteomics. Current Opinion in Chemical Biology 2005, 9, (1), 14-19.

Park, J.; Hu, Y. H.; Murthy, T. V. S.; Vannberg, F.; Shen, B. H.; Rolfs, A.; Hutti, J. E.; Cantley, L. C.; LaBaer, J.; Harlow, E.; Brizuela, L., Building a human kinase gene repository: Bioinformatics, molecular cloning, and functional validation. Proceedings of the National Academy of Sciences of the United States of America 2005, 102, (23), 8114-8119.

Pearlberg, J.; Degot, S.; Endege, W.; Park, J.; Davies, J.; Gelfand, E.; Sawyer, J.; Conery, A.; Doench, J.; Li, W.; Gonzalez, L.; Boyce, F. M.; Brizuela, L.; LaBaer, J.; Grueneberg, D.; Harlow, E., Screens using RNAi and cDNA expression as surrogates for genetics in mammalian tissue culture cells. Cold Spring Harb Symp Quant Biol 2005, 70, 449-59.

Ramachandran, N.; Larson, D. N.; Stark, P. R. H.; Hainsworth, E.; LaBaer, J., Emerging tools for real-time label-free detection of interactions on functional protein microarrays. Febs Journal 2005, 272, (21), 5412-5425.

Schiwek, D.; LaBaer, J.; Hines, L., Self-assembling protein microarrays for mapping protein-protein interactions among 1300 breast cancer-related proteins. Molecular & Cellular Proteomics 2005, 4, (8), S55-S55.

Butcher, R. A.; Bhullar, B. S.; Perlstein, E. O.; Marsischky, G.; LaBaer, J.; Schreiber, S. L., Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nature Chemical Biology 2006, 2, (2), 103-109.

Chatterjee, D. K.; LaBaer, J., Protein technologies - Editorial overview. Current Opinion in Biotechnology 2006, 17, (4), 334-336.

Cooper, A. A.; Gitler, A. D.; Cashikar, A.; Haynes, C. M.; Hill, K. J.; Bhullar, B.; Liu, K. N.; Xu, K. X.; Strathearn, K. E.; Liu, F.; Cao, S. S.; Caldwell, K. A.; Caldwell, G. A.; Marsischky, G.; Kolodner, R. D.; LaBaer, J.; Rochet, J. C.; Bonini, N. M.; Lindquist, S., alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 2006, 313, (5785), 324-328.

Haab, B. B.; Paulovich, A. G.; Anderson, N. L.; Clark, A. M.; Downing, G. J.; Hermjakob, H.; LaBaer, J.; Uhlen, M., A reagent resource to identify proteins and peptides of interest for the cancer community - A workshop report. Molecular & Cellular Proteomics 2006, 5, (10), 1996-2007.

Park J, LaBaer J. Recombinational cloning. Curr Protoc Mol Biol. 2006 May;Chapter 3:Unit 3.20.

Braun P, LaBaer J.  High Throughput Purification of Proteins from Escherichia Coli in Cell Biology: A Laboratory Handbook, 3rd Edition, Volume 4. Elsevier Academic Press: Burlington, MA 2006: 73- 77.

LaBaer, J., Functional proteomics for biomarker and target discovery. Molecular & Cellular Proteomics 2006, 5, (10), 557.

Ramachandran, N.; Hainsworth, E.; Demirkan, G.; LaBaer, J., On-chip protein synthesis for making microarrays. Methods Mol Biol 2006, 328, 1-14.

Witt, A. E.; Hines, L. M.; Collins, N. L.; Hu, Y. H.; Gunawardane, R. N.; Moreira, D.; Raphael, J.; Jepson, D.; Koundinya, M.; Rolfs, A.; Taron, B.; Isakoff, S. J.; Brugge, J. S.; LaBaer, J., Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer. Journal of Proteome Research 2006, 5, (3), 599-610.

Gonzalez, L. G.; Park, J.; Geistlinger, T. R.; Pearlberg, J.; Endege, W.; Degot, S.; Sawyer, J.; Hu, Y.; Harlow, E.; LaBaer, J., Kinome survey of molecular pathways lead to tamoxifen-resistant breast cancer cell growth. Breast Cancer Research and Treatment 2007, 106, S205-S205.

Hu, Y. H.; Rolfs, A.; Bhullar, B.; Murthy, T. V. S.; Zhu, C.; Berger, M. F.; Camargo, A. A.; Kelley, F.; McCarron, S.; Jepson, D.; Richardson, A.; Raphael, J.; Moreira, D.; Taycher, E.; Zuo, D. M.; Mohr, S.; Kane, M. F.; Williamson, J.; Simpson, A.; Bulyk, M. L.; Harlow, E.; Marsischky, G.; Kolodner, R. D.; LaBaer, J., Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Research 2007, 17, (4), 536-543.

Langlais, C.; Guilleaume, B.; Wermke, N.; Scheuermann, T.; Ebert, L.; LaBaer, J.; Korn, B., A systematic approach for testing expression of human full-length proteins in cell-free expression systems. Bmc Biotechnology 2007, 7, 11.

Murthy, T.; Rolfs, A.; Hu, Y. H.; Shi, Z. W.; Raphael, J.; Moreira, D.; Kelley, F.; McCarron, S.; Jepson, D.; Taycher, E.; Zuo, D. M.; Mohr, S. E.; Fernandez, M.; Brizuela, L.; LaBaer, J., A Full-Genomic Sequence-Verified Protein-Coding Gene Collection for Francisella tularensis. Plos One 2007, 2, (6), 7.

Taycher, E.; Rolfs, A.; Hu, Y.; Zuo, D.; Mohr, S. E.; Williamson, J.; LaBaer, J., A novel approach to sequence validating protein expression clones with automated decision making. Bmc Bioinformatics 2007, 8, 16.

Xu, L.; Zhu, J. D.; Hu, X. F.; Zhu, H.; Kim, H. T.; LaBaer, J.; Goldberg, A.; Yuan, J. Y., c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1. Molecular Cell 2007, 28, (5), 914-922.

Zuo, D. M.; Mohr, S. E.; Hu, Y. H.; Taycher, E.; Rolfs, A.; Kramer, J.; Williamson, J.; LaBaer, J., PlasmID: a centralized repository for plasmid clone information and distribution. Nucleic Acids Research 2007, 35, D680-D684.

Anderson, K. S.; Ramachandran, N.; Wong, J.; Raphael, J. V.; Hainsworth, E.; Demirkan, G.; Cramer, D.; Aronzon, D.; Hodi, F. S.; Harris, L.; Logvinenko, T.; LaBaer, J., Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. Journal of Proteome Research 2008, 7, (4), 1490-1499.

Barderas, R.; Ramachandran, N.; Hainsworth, G.; Wong, J.; Raphael, J.; Cramer, D.; LaBaer, J.; Anderson, K. S., Distinct patterns of immunoreactivity from p53-specific autoantibodies in breast and ovarian cancer patient sera. Cancer Biomarkers 2008, 4, (3), 131-132.

Hughes, S. R.; Dowd, P. F.; Hector, R. E.; Panavas, T.; Sterner, D. E.; Qureshi, N.; Bischoff, K. M.; Bang, S. S.; Mertens, J. A.; Johnson, E. T.; Li, X. L.; Jackson, J. S.; Caughey, R. J.; Riedmuller, S. B.; Bartolett, S.; Liu, S.; Rich, J. O.; Farrelly, P. J.; Butt, T. R.; LaBaer, J.; Cotta, M. A., Lycotoxin-1 insecticidal peptide optimized by amino acid scanning mutagenesis and expressed as a coproduct in an ethanologenic Saccharomyces cerevisiae strain. Journal of Peptide Science 2008, 14, (9), 1039-1050.

LaBaer, J., Autoantibody screening using protein microarrays. Cancer Biomarkers 2008, 4, (3), 179-180.

Link, A. J.; LaBaer, J., Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions. Protocol 2: Detection of Query Proteins on NAPPA Slides. CSH Protoc 2008, pdb prot5109.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 7: Detecting DNA on NAPPA Slides. CSH Protoc 2008, pdb prot5062.

Link, A. J.; LaBaer, J., Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions. Protocol 1: Coexpression of Query Protein on NAPPA Slides. CSH Protoc 2008, pdb prot5108.

Link, A. J.; LaBaer, J., Using the Nucleic Acid Programmable Protein Array (NAPPA) for Identifying Protein-Protein Interactions: General Guidelines. CSH Protoc 2008, pdb ip62.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 6: Detecting Proteins on NAPPA Slides. CSH Protoc 2008, pdb prot5061.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 5: Expressing Proteins on NAPPA Slides. CSH Protoc 2008, pdb prot5060.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 4: DNA Biotinylation, Precipitation, and Arraying of Samples. CSH Protoc 2008,  pdb prot5059.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 3: Isolating DNA Plasmids in a 96-Well Plate Format. CSH Protoc 2008, pdb prot5058.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 2: Preparing Bacterial Cultures in a 96-Well Format. CSH Protoc 2008, pdb prot5057.

Link, A. J.; LaBaer, J., Construction of Nucleic Acid Programmable Protein Arrays (NAPPA) 1: Coating Glass Slides with Amino Silane. CSH Protoc 2008, pdb prot5056.

Link, A. J.; LaBaer, J., High-Throughput Cloning of Open Reading Frames (ORFs): Assembling Large Sets of Expression Constructs. CSH Protoc 2008, pdb prot5050.

Ramachandran, N.; Anderson, K. S.; Raphael, J. V.; Hainsworth, E.; Sibani, S.; Montor, W. R.; Pacek, M.; Wong, J.; Eljanne, M.; Sanda, M. G.; Hu, Y. H.; Logvinenko, T.; LaBaer, J., Tracking humoral responses using self assembling protein microarrays. Proteomics Clinical Applications 2008, 2, (10-11), 1518-1527.

Ramachandran, N.; Raphael, J. V.; Hainsworth, E.; Demirkan, G.; Fuentes, M. G.; Rolfs, A.; Hu, Y. H.; LaBaer, J., Next-generation high-density self-assembling functional protein arrays. Nature Methods 2008, 5, (6), 535-538.

Ramachandran, N.; Srivastava, S.; LaBaer, J., Applications of protein microarrays for biomarker discovery. Proteomics Clinical Applications 2008, 2, (10-11), 1444-1459.

Rolfs, A.; Hu, Y.; Ebert, L.; Hoffmann, D.; Zuo, D.; Ramachandran, N.; Raphael, J.; Kelley, F.; McCarron, S.; Jepson, D. A.; Shen, B.; Baqui, M. M. A.; Pearlberg, J.; Taycher, E.; DeLoughery, C.; Hoerlein, A.; Korn, B.; LaBaer, J., A Biomedically Enriched Collection of 7000 Human ORF Clones. Plos One 2008, 3, (1), 8.

Rolfs, A.; Montor, W. R.; Yoon, S. S.; Hu, Y. H.; Bhullar, B.; Kelley, F.; McCarron, S.; Jepson, D. A.; Shen, B. H.; Taycher, E.; Mohr, S. E.; Zuo, D. M.; Williamson, J.; Mekalanos, J.; LaBaer, J., Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, (11), 4364-4369.

Slagowski, N. L.; Kramer, R. W.; Morrison, M. F.; LaBaer, J.; Lesser, C. F., A functional genomic yeast screen to identify pathogenic bacterial proteins. Plos Pathogens 2008, 4, (1), 12.

Srivastava, S.; LaBaer, J., Nanotubes light up protein arrays. Nature Biotechnology 2008, 26, (11), 1244-1246.

Berman HM, Westbrook JD, Gabanyi MJ, Tao W, Shah R, Kouranov A, Schwede T, Arnold K, Kiefer F, Bordoli L, Kopp J, Podvinec M, Adams PD, Carter LG, Minor W, Nair R, LaBaer J. The protein structure initiative structural genomics knowledgebase. Nucleic Acids Res. 2009 Jan;37(Database issue):D365-8. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686438)

Anderson, K. S.; Hodi, F. S.; Sasada, T.; Canning, C.; Hassett, M.; Mayer, E.; Hannagan, K.; Wong, J.; Colson, Y.; Shoji, B.; Najita, J.; Sibani, S.; LaBaer, J.; Winer, E. P.; Dranoff, G., A phase I study of an autologous GM-CSF-secreting breast cancer vaccine. Cancer Research 2009, 69, (2), 288S-288S.

Anderson, K. S.; Sibani, S.; Wong, J.; Hainsworth, E.; Mendoza, E. A.; Eugene, R.; Raphael, J.; Logvinenko, T.; Ramachandran, N.; Godwin, A.; Marks, J.; Engstrom, P.; LaBaer, J., Using custom protein microarrays to identify autoantibody biomarkers for the early detection of breast cancer. Cancer Research 2009, 69, (2), 157S-157S.

Gonzalez-Malerva, L. G.; Park, J.; Zou, L.; Hu, Y.; Moradpour, Z.; Pearlberg, J.; Harlow, E.; LaBaer, J., Autophagy and Tamoxifen Resistance in Breast Cancer. Cancer Research 2009, 69, (24), 810S-811S.

Hughes, S. R.; Hector, R. E.; Rich, J. O.; Qureshi, N.; Bischoff, K. M.; Dien, B. S.; Saha, B. C.; Liu, S. Q.; Cox, E. J.; Jackson, J. S.; Sterner, D. E.; Butt, T. R.; LaBaer, J.; Cotta, M. A., Automated Yeast Mating Protocol Using Open Reading Frames from Saccharomyces cerevisiae Genome to Improve Yeast Strains for Cellulosic Ethanol Production. Jala 2009, 14, (4), 190-199.

Hughes, S. R.; Rich, J. O.; Bischoff, K. M.; Hector, R. E.; Qureshi, N.; Saha, B. C.; Dien, B. S.; Liu, S. Q.; Jackson, J. S.; Sterner, D. E.; Butt, T. R.; LaBaer, J.; Cotta, M. A., Automated Yeast Transformation Protocol to Engineer Saccharomyces cerevisiae Strains for Cellulosic Ethanol Production with Open Reading Frames That Express Proteins Binding to Xylose Isomerase Identified Using a Robotic Two-Hybrid Screen. Jala 2009, 14, (4), 200-212.

Hughes, S. R.; Sterner, D. E.; Bischoff, K. M.; Hector, R. E.; Dowd, P. F.; Qureshi, N.; Bang, S. S.; Grynaviski, N.; Chakrabarty, T.; Johnson, E. T.; Dien, B. S.; Mertens, J. A.; Caughey, R. J.; Liu, S. Q.; Butt, T. R.; LaBaer, J.; Cotta, M. A.; Rich, J. O., Engineered Saccharomyces cerevisiae strain for improved xylose utilization with a three-plasmid SUMO yeast expression system. Plasmid 2009, 61, (1), 22-38.

Link, A. J.; LaBaer, J., In-gel trypsin digest of gel-fractionated proteins. Cold Spring Harb Protoc 2009, (2), pdb prot5110.

Montor, W. R.; Huang, J.; Hu, Y. H.; Hainsworth, E.; Lynch, S.; Kronish, J. W.; Ordonez, C. L.; Logvinenko, T.; Lory, S.; LaBaer, J., Genome-Wide Study of Pseudomonas aeruginosa Outer Membrane Protein Immunogenicity Using Self-Assembling Protein Microarrays. Infection and Immunity 2009, 77, (11), 4877-4886.

Murphy, R. F.; LaBaer, J., Locations Everyone: Lights, Camera, Action! Journal of Proteome Research 2009, 8, (1), 1-1.

Sheikh, A.; Khanam, F.; Rahman, T.; Pacek, M.; Hu, Y. H.; Baresch, A.; Bhuiyan, M. S.; Rollins, S.; Citorik, R.; Kalsy, A.; Charles, R.; LaRocque, R. C.; LaBaer, J.; Calderwood, S. B.; Harris, J. B.; Qadri, F.; Ryan, E. T., Evaluation Of Interferon-Gamma Responses In Patients With Salmonella Enterica Serovar Typhi Bacteremia In Dhaka, Bangladesh. American Journal of Tropical Medicine and Hygiene 2009, 81, (5), 1144.

Thanawastien, A.; Montor, W. R.; LaBaer, J.; Mekalanos, J. J.; Yoon, S. S., Vibrio cholerae Proteome-Wide Screen for Immunostimulatory Proteins Identifies Phosphatidylserine Decarboxylase as a Novel Toll-Like Receptor 4 Agonist. Plos Pathogens 2009, 5, (8), 11.

Wong, J.; Sibani, S.; Lokko, N. N.; LaBaer, J.; Anderson, K. S., Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays. Journal of Immunological Methods 2009, 350, (1-2), 171-182.

Zhang, L. L.; Villa, N. Y.; Rahman, M. M.; Smallwood, S.; Shattuck, D.; Neff, C.; Dufford, M.; Lanchbury, J. S.; LaBaer, J.; McFadden, G., Analysis of Vaccinia Virus-Host Protein-Protein Interactions: Validations of Yeast Two-Hybrid Screenings. Journal of Proteome Research 2009, 8, (9), 4311-4318.

Zhu, C.; Byers, K.; McCord, R. P.; Shi, Z. W.; Berger, M. F.; Newburger, D. E.; Saulrieta, K.; Smith, Z.; Shah, M. V.; Radhakrishnan, M.; Philippakis, A. A.; Hu, Y. H.; De Masi, F.; Pacek, M.; Rolfs, A.; Murthy, T.; LaBaer, J.; Bulyk, M. L., High-resolution DNA-binding specificity analysis of yeast transcription factors. Genome Research 2009, 19, (4), 556-566.

Anderson, K. S.; Wong, J.; Vitonis, A.; Crum, C. P.; Sluss, P. M.; LaBaer, J.; Cramer, D., p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer. Cancer Epidemiology Biomarkers & Prevention 2010, 19, (3), 859-868.

Ceroni, A.; Sibani, S.; Baiker, A.; Pothineni, V. R.; Bailer, S. M.; LaBaer, J.; Haas, J.; Campbell, C. J., Systematic analysis of the IgG antibody immune response against varicella zoster virus (VZV) using a self-assembled protein microarray. Molecular Biosystems 2010, 6, (9), 1604-1610.

Cormier, C. Y.; Mohr, S. E.; Zuo, D. M.; Hu, Y. H.; Rolfs, A.; Kramer, J.; Taycher, E.; Kelley, F.; Fiacco, M.; Turnbull, G.; LaBaer, J., Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community. Nucleic Acids Research 2010, 38, D743-D749.

Jarvis, D. L.; Geisler, C.; Aumiller, J.; Jacob, B.; Moremen, K. W.; Steel, J.; LaBaer, J., Repository of Recombinant Expression Constructs for Mammalian Glycosylation Enzymes: Baculovirus Vectors for Glycosyltransferase and Glycoside Hydrolase Production in Insect Cells. Glycobiology 2010, 20, (11), 196.

Moremen, K. W.; Naim, A. V.; Meng, L.; Ramiah, A.; Gao, Z.; Johnson, R.; Samli, E. F.; Strachan, H.; Xiang, Y.; Scott, I.; Gilbert, H. J.; Jarvis, D. L.; Steel, J.; LaBaer, J., Repository of Recombinant Expression Constructs for Mammalian Glycosylation Enzymes: Production of Glycosyltransferases and Glycoside Hydrolases in Mammalian Cells. Glycobiology 2010, 20, (11), 21.

Ramirez, A. B.; Loch, C. M.; Zhang, Y. Z.; Liu, Y.; Wang, X. H.; Wayner, E. A.; Sargent, J. E.; Sibani, S.; Hainsworth, E.; Mendoza, E. A.; Eugene, R.; LaBaer, J.; Urban, N. D.; McIntosh, M. W.; Lampe, P. D., Use of a Single-Chain Antibody Library for Ovarian Cancer Biomarker Discovery. Molecular & Cellular Proteomics 2010, 9, (7), 1449-1460.

Wright, C.; Sibani, S.; Trudgian, D.; Fischer, R.; Kessler, B.; LaBaer, J.; Bowness, P., Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays. Mol Cell Proteomics 2010.

Anderson, K. S.; Sibani, S.; Wallstrom, G.; Qiu, J.; Mendoza, E. A.; Raphael, J.; Hainsworth, E.; Montor, W. R.; Wong, J.; Park, J. G.; Lokko, N.; Logvinenko, T.; Ramachandran, N.; Godwin, A. K.; Marks, J.; Engstrom, P.; LaBaer, J., Protein Microarray Signature of Autoantibody Biomarkers for the Early Detection of Breast Cancer. Journal of Proteome Research 2011, 10, (1), 85-96.

Anderson, K. S.; Wong, J.; D'Souza, G.; Riemer, A. B.; Lorch, J.; Haddad, R.; Pai, S. I.; Longtine, J.; McClean, M.; LaBaer, J.; Kelsey, K. T.; Posner, M., Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. British Journal of Cancer 2011, 104, (12), 1896-1905.

Cormier, C. Y.; Park, J. G.; Fiacco, M.; Steel, J.; Hunter, P.; Kramer, J.; Singla, R.; LaBaer, J., PSI:Biology-materials repository: a biologist's resource for protein expression plasmids. J Struct Funct Genomics 2011, 12, (2), 55-62.

Gonzalez-Malerva, L.; Park, J.; Zou, L. H.; Hu, Y. H.; Moradpour, Z.; Pearlberg, J.; Sawyer, J.; Stevens, H.; Harlow, E.; LaBaer, J., High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy. Proceedings of the National Academy of Sciences of the United States of America 2011, 108, (5), 2058-2063.

Hancock, W.; LaBaer, J.; Marko-Varga, G. A., Journal of Proteome Research-10th Anniversary. Journal of Proteome Research 2011, 10, (1), 1-2.

Link, A. J.; LaBaer, J., Setup and demonstration of a nanoelectrospray ionization source and tandem mass spectrometry. Cold Spring Harb Protoc 2011, (7).

Link, A. J.; LaBaer, J., Off-line desalting of peptide mixtures. Cold Spring Harb Protoc 2011, (1), prot5591.

Link, A. J.; LaBaer, J., Solution protein digest. Cold Spring Harb Protoc 2011, (1), pdb prot5569.

Miersch, S.; LaBaer, J., Nucleic Acid programmable protein arrays: versatile tools for array-based functional protein studies. Curr Protoc Protein Sci 2011, Chapter 27, Unit27 2.

Sheikh, A.; Khanam, F.; Sayeed, M. A.; Rahman, T.; Pacek, M.; Hu, Y.; Rollins, A.; Bhuiyan, M. S.; Rollins, S.; Kalsy, A.; Arifuzzaman, M.; Leung, D. T.; Sarracino, D. A.; Krastins, B.; Charles, R. C.; Larocque, R. C.; Cravioto, A.; Calderwood, S. B.; Brooks, W. A.; Harris, J. B.; LaBaer, J.; Qadri, F.; Ryan, E. T., Interferon-gamma and Proliferation Responses to Salmonella enterica Serotype Typhi Proteins in Patients with S. Typhi Bacteremia in Dhaka, Bangladesh. PLoS Negl Trop Dis 2011, 5, (6), e1193.

Selected Publications

2014

  • Seiler CY, Park JG, Sharma A, Hunter P, Surapaneni P, Sedillo C, Field J, Algar R, Price A, Steel J, Throop A, Fiacco M, LaBaer J.. DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research.. Nucleic Acids Res (2014) Refereed Articles.

2013

  • Festa, F.; Steel, J.; Bian, X.; LaBaer, J.. High-throughput cloning and expression library creation for functional proteomics.. Proteomics (2013) Refereed Articles.
  • Kang D-W, P. J., Ilhan ZE, Wallstrom G, LaBaer J, Adams, JB, Krajmalnik_Brown. Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children.. PLoS ONE (2013) Refereed Articles.
  • Lee, J. R.; Magee, D. M.; Gaster, R. S.; LaBaer, J.; Wang, S. X.. Emerging protein array technologies for proteomics.. Expert review of proteomics (2013) Refereed Articles.
  • Miersch, S.; Bian, X.; Wallstrom, G.; Sibani, S.; Logvinenko, T.; Wasserfall, C. H.; Schatz, D.; Atkinson, M.; Qiu, J.; LaBaer, J.. Serological autoantibody profiling of type 1 diabetes by protein arrays.. Journal of Proteomics (2013) Refereed Articles.
  • Skates, S. J.; Gillette, M. A.; LaBaer, J.; Carr, S. A.; Anderson, L.; Liebler, D. C.; Ransohof, D.; Rifai, N.; Kondratovich, M.; Tezak, Z.; Mansfield, E.; Oberg, A. L.; Wright, I.; Barnes, G.; Gail, M.; Mesri, M.; Kinsinger, C. R.; Rodriguez, H.; Boja, E. Statistical Design for Biospecimen Cohort Size in Proteomics-based Biomarker Discovery and Verification Studies.. Journal of Proteome Research (2013) Refereed Articles.
  • Spera, R.; Festa, F.; Bragazzi, N.; Pechkova, E.; LaBaer, J.; Nicolini, C.. Conductometric Monitoring of Protein-Protein Interactions.. Journal of Proteome Research (2013) Refereed Articles.
  • Wallstrom, G.; Anderson, K. S.; LaBaer, J.. Biomarker discovery for heterogeneous diseases. Cancer epidemiology, biomarkers & prevention. American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. (2013) Refereed Articles.
  • Wang, J.; Barker, K.; Steel, J.; Park, J.; Saul, J.; Festa, F.; Wallstrom, G.; Yu, X.; Bian, X.; Anderson, K. S.; Figueroa, J. D.; LaBaer, J.; Qiu, J.. A versatile protein microarray platform enabling antibody profiling against denatured proteins.. Proteomics Clinical Applications (2013) Refereed Articles.
  • Yu, X.; Wallstrom, G.; Magee, D. M.; Qiu, J.; Mendoza, D. E.; Wang, J.; Bian, X.; Graves, M.; LaBaer, J.. Quantifying antibody binding on protein microarrays using microarray nonlinear calibration.. BioTechniques (2013) Refereed Articles.

2012

  • Festa F, Rollins SM, Vattem K, Hathaway M, Lorenz P, Mendoza EA, Yu X, Qiu J, Kilmer G, Jensen P, Webb B, Ryan ET, LaBaer J.. Robust microarray production of freshly expressed proteins in a human milieu.. Proteomics Clin Appl (2012) Refereed Articles.
  • Gibson, D.S.; Qiu, J.; Mendoza, E.A.; Barker, K.; Rooney, M.E., LaBaer, J.. Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays.. Arthritis Res Ther. 2012 Apr 17;14(2):R77. [Epub ahead of print] (2012) Refereed Articles.
  • Hood LE, Omenn GS, Moritz RL, Aebersold R, Yamamoto KR, Amos M, Hunter-Cevera J, Locascio L; Workshop Participants.. New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.. Proteomics. (2012) Refereed Articles.
  • LaBaer, J.. Improving international research with clinical specimens: 5 achievable objectives (Perspective).. Journal of Proteome Research (2012) Refereed Articles.
  • Manzano-Rom?n R, D?az-Mart?n V, Gonz?lez-Gonz?lez M, Matarraz S, Alvarez-Prado AF, Labaer J, Orfao A, P?rez-S?nchez R, Fuentes M.. Self-assembled Protein Arrays from an Ornithodoros moubata Salivary Gland Expression Library.. J Proteome Res (2012) Refereed Articles.
  • Takulapalli, B.R., Qiu J., Magee, D.M., Kahn. P., Brunner, A., Barker, K., Means, S., Miersch, S., Bian, X., Mendoza, A., Festa, F., Syal, K., Park, J.G., LaBaer, J., Wiktor, P.. High Density Diffusion-Free Nanowell Arrays.. Journal of Proteome Research (2012) Refereed Articles.
  • Wang J, Barker K, Steel J, Park J, Saul J, Festa F, Wallstrom G, Yu X, Bian X, Anderson KS, Figueroa J, Labaer J, Qiu J.. A versatile protein microarray platform enabling antibody profiling against denatured proteins.. Proteomics Clin Appl. (2012) Refereed Articles.
  • Wright C., Sibani S., Trudgian D., Fischer R., Kessler B., LaBaer J., Bowness P.. Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic Acid programmable protein arrays.. Mol Cell Proteomics (2012) Refereed Articles.

2011

  • Anderson, K. S.; Sibani, S.; Wallstrom, G.; Qiu, J.; Mendoza, E. A.; Raphael, J.; Hainsworth, E.; Montor, W. R.; Wong, J.; Park, J. G.; Lokko, N.; Logvinenko, T.; Ramachandran, N.; Godwin, A. K.; Marks, J.; Engstrom, P.; LaBaer, J.. Protein Microarray Signature of Autoantibody Biomarkers for the Early Detection of Breast Cancer.. Journal of Proteome Research (2011) Refereed Articles.
  • Anderson, K. S.; Wong, J.; D'Souza, G.; Riemer, A. B.; Lorch, J.; Haddad, R.; Pai, S. I.; Longtine, J.; McClean, M.; LaBaer, J.; Kelsey, K. T.; Posner, M.. Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer.. British Journal of Cancer (2011) Refereed Articles.
  • Cormier, C. Y.; Park, J. G.; Fiacco, M.; Steel, J.; Hunter, P.; Kramer, J.; Singla, R.; LaBaer, J.. PSI: Biology-materials repository: a biologist's resource for protein expression plasmids.. J Struct Funct Genomics (2011) Refereed Articles.
  • Gibson, D.S.; Rooney, M.E.; Finnegan, S.F.; Qiu, J.; Thompson, D.C.; LaBaer, J.; Pennington, S.R.; Duncan, M.W.. Biomarkers in rheumatology, now and in the future.. Rheumatology 2011 (2011) Refereed Articles.
  • Gonzalez-Malerva, L.; Park, J.; Zou, L. H.; Hu, Y. H.; Moradpour, Z.; Pearlberg, J.; Sawyer, J.; Stevens, H.; Harlow, E.; LaBaer, J.. High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy.. Proceedings of the National Academy of Sciences of the United States of America (2011) Refereed Articles.
  • Hancock, W.; LaBaer, J.; Marko-Varga, G. A.. Journal of Proteome Research-10th Anniversary. Journal of Proteome Research (2011) Refereed Articles.
  • Link, A. J.; LaBaer, J.. Trichloroacetic acid (TCA) precipitation of proteins.. Cold Spring Harb Protoc (2011) Refereed Articles.
  • Link, A. J.; LaBaer, J.. Off-line desalting of peptide mixtures.. Cold Spring Harb Protoc (2011) Refereed Articles.
  • Link, A. J.; LaBaer, J.. Setup and demonstration of a nanoelectrospray ionization source and tandem mass spectrometry. Cold Spring Harb Protoc (2011) Refereed Articles.
  • Link, A. J.; LaBaer, J.. Solution protein digest.. Cold Spring Harb Protoc (2011) Refereed Articles.
  • Miersch, S.; LaBaer, J.. Nucleic Acid programmable protein arrays: versatile tools for array-based functional protein studies.. Curr Protoc Protein Sci (2011) Refereed Articles.
  • Qiu, J.; LaBaer, J.. Nucleic acid programmable protein array a just-in-time multiplexed protein expression and purification platform.. Methods Enzymol (2011) Refereed Articles.
  • Sheikh, A.; Khanam, F.; Sayeed, M. A.; Rahman, T.; Pacek, M.; Hu, Y.; Rollins, A.; Bhuiyan, M. S.; Rollins, S.; Kalsy, A.; Arifuzzaman, M.; Leung, D. T.; Sarracino, D. A.; Krastins, B.; Charles, R. C.; Larocque, R. C.; Cravioto, A.; Calderwood, S. B.; Bro. Interferon-gamma and Proliferation Responses to Salmonella enterica Serotype Typhi Proteins in Patients with S. Typhi Bacteremia in Dhaka, Bangladesh.. PLoS Negl Trop Dis (2011) Refereed Articles.
  • Spera, R.; Labaer, J.; Nicolini, C.. MALDI-TOF characterization of NAPPA-generated proteins.. J Mass Spectrom (2011) Refereed Articles.

2010

  • Anderson, K. S.; Wong, J.; Vitonis, A.; Crum, C. P.; Sluss, P. M.; LaBaer, J.; Cramer, D.. p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer. Cancer Epidemiology Biomarkers & Prevention (2010) Refereed Articles.
  • Ceroni, A.; Sibani, S.; Baiker, A.; Pothineni, V. R.; Bailer, S. M.; LaBaer, J.; Haas, J.; Campbell, C. J.. Systematic analysis of the IgG antibody immune response against varicella zoster virus (VZV) using a self-assembled protein microarray.. Molecular Biosystems (2010) Refereed Articles.
  • Cormier, C. Y.; Mohr, S. E.; Zuo, D. M.; Hu, Y. H.; Rolfs, A.; Kramer, J.; Taycher, E.; Kelley, F.; Fiacco, M.; Turnbull, G.; LaBaer, J.. Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community.. Nucleic Acids Research (2010) Refereed Articles.
  • Jarvis, D. L.; Geisler, C.; Aumiller, J.; Jacob, B.; Moremen, K. W.; Steel, J.; LaBaer, J.. Repository of Recombinant Expression Constructs for Mammalian Glycosylation Enzymes: Baculovirus Vectors for Glycosyltransferase and Glycoside Hydrolase Production in Insect Cells.. Glycobiology (2010) Refereed Articles.
  • Moremen, K. W.; Naim, A. V.; Meng, L.; Ramiah, A.; Gao, Z.; Johnson, R.; Samli, E. F.; Strachan, H.; Xiang, Y.; Scott, I.; Gilbert, H. J.; Jarvis, D. L.; Steel, J.; LaBaer, J.. Repository of Recombinant Expression Constructs for Mammalian Glycosylation Enzymes: Production of Glycosyltransferases and Glycoside Hydrolases in Mammalian Cells.. Glycobiology (2010) Refereed Articles.
  • Ramirez, A. B.; Loch, C. M.; Zhang, Y. Z.; Liu, Y.; Wang, X. H.; Wayner, E. A.; Sargent, J. E.; Sibani, S.; Hainsworth, E.; Mendoza, E. A.; Eugene, R.; LaBaer, J., Urban, N. D.; McIntosh, M. W.; Lampe, P. D.. Use of a Single-Chain Antibody Library for Ovarian Cancer Biomarker Discovery.. Molecular & Cellular Proteomics (2010) Refereed Articles.
  • Wright, C.; Sibani, S.; Trudgian, D.; Fischer, R.; Kessler, B.; LaBaer, J.; Bowness, P.. Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays.. Mol Cell Proteomics (2010) Refereed Articles.

2009

  • 87. Hughes, S. R.; Sterner, D. E.; Bischoff, K. M.; Hector, R. E.; Dowd, P. F.; Qureshi, N.; Bang, S. S.; Grynaviski, N.; Chakrabarty, T.; Johnson, E. T.; Dien, B. S.; Mertens, J. A.; Caughey, R. J.; Liu, S. Q.; Butt, T. R.; LaBaer, J.; Cotta, M. A.; Rich. Engineered Saccharomyces cerevisiae strain for improved xylose utilization with a three-plasmid SUMO yeast expression system.. Plasmid (2009) Refereed Articles.
  • Anderson, K. S.; Hodi, F. S.; Sasada, T.; Canning, C.; Hassett, M.; Mayer, E.; Hannagan, K.; Wong, J.; Colson, Y.; Shoji, B.; Najita, J.; Sibani, S.; LaBaer, J.; Winer, E. P.; Dranoff, G.. A phase I study of an autologous GM-CSF-secreting breast cancer vaccine.. Cancer Research (2009) Refereed Articles.
  • Anderson, K. S.; Sibani, S.; Wong, J.; Hainsworth, E.; Mendoza, E. A.; Eugene, R.; Raphael, J.; Logvinenko, T.; Ramachandran, N.; Godwin, A.; Marks, J.; Engstrom, P.; LaBaer, J.. Using custom protein microarrays to identify autoantibody biomarkers for the early detection of breast cancer.. Cancer Research (2009) Refereed Articles.
  • Gonzalez-Malerva, L. G.; Park, J.; Zou, L.; Hu, Y.; Moradpour, Z.; Pearlberg, J.; Harlow, E.; LaBaer, J.. Autophagy and Tamoxifen Resistance in Breast Cancer.. Cancer Research 2 (2009) Refereed Articles.
  • Hughes, S. R.; Hector, R. E.; Rich, J. O.; Qureshi, N.; Bischoff, K. M.; Dien, B. S.; Saha, B. C.; Liu, S. Q.; Cox, E. J.; Jackson, J. S.; Sterner, D. E.; Butt, T. R.; LaBaer, J.; Cotta, M. A.. Automated Yeast Mating Protocol Using Open Reading Frames from Saccharomyces cerevisiae Genome to Improve Yeast Strains for Cellulosic Ethanol Production.. Jala (2009) Refereed Articles.
  • Hughes, S. R.; Rich, J. O.; Bischoff, K. M.; Hector, R. E.; Qureshi, N.; Saha, B. C.; Dien, B. S.; Liu, S. Q.; Jackson, J. S.; Sterner, D. E.; Butt, T. R.; LaBaer, J.; Cotta, M. A.. Automated Yeast Transformation Protocol to Engineer Saccharomyces cerevisiae Strains for Cellulosic Ethanol Production with Open Reading Frames That Express Proteins Binding to Xylose Isomerase Identified Using a Robotic Two-Hybrid Screen.. Jala (2009) Refereed Articles.
  • Link, A. J. and J. LaBaer. Proteomics: A Cold Spring Harbor Laboratory Course Manual. (2009) Authored Books.
  • Montor, W. R.; Huang, J.; Hu, Y. H.; Hainsworth, E.; Lynch, S.; Kronish, J. W.; Ordonez, C. L.; Logvinenko, T.; Lory, S.; LaBaer, J.. Genome-Wide Study of Pseudomonas aeruginosa Outer Membrane Protein Immunogenicity Using Self-Assembling Protein Microarrays.. Infection and Immunity (2009) Refereed Articles.
  • Murphy, R. F.; LaBaer, J.. Locations Everyone: Lights, Camera, Action!. Journal of Proteome Research (2009) Refereed Articles.
  • Sheikh, A.; Khanam, F.; Rahman, T.; Pacek, M.; Hu, Y. H.; Baresch, A.; Bhuiyan, M. S.; Rollins, S.; Citorik, R.; Kalsy, A.; Charles, R.; LaRocque, R. C.; LaBaer, J.; Calderwood, S. B.; Harris, J. B.; Qadri, F.; Ryan, E. T.. Evaluation Of Interferon-Gamma Responses In Patients With Salmonella Enterica Serovar Typhi Bacteremia In Dhaka, Bangladesh.. American Journal of Tropical Medicine and Hygiene (2009) Refereed Articles.
  • Thanawastien, A.; Montor, W. R.; LaBaer, J.; Mekalanos, J. J.; Yoon, S. S.. Vibrio cholerae Proteome-Wide Screen for Immunostimulatory Proteins Identifies Phosphatidylserine Decarboxylase as a Novel Toll-Like Receptor 4 Agonist.. Plos Pathogens (2009) Refereed Articles.
  • Wong, J.; Sibani, S.; Lokko, N. N.; LaBaer, J.; Anderson, K. S.. Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays.. Journal of Immunological Methods (2009) Refereed Articles.
  • Zhang, L. L.; Villa, N. Y.; Rahman, M. M.; Smallwood, S.; Shattuck, D.; Neff, C.; Dufford, M.; Lanchbury, J. S.; LaBaer, J.; McFadden, G.. Analysis of Vaccinia Virus-Host Protein-Protein Interactions: Validations of Yeast Two-Hybrid Screenings.. Journal of Proteome Research (2009) Refereed Articles.
  • Zhu, C.; Byers, K.; McCord, R. P.; Shi, Z. W.; Berger, M. F.; Newburger, D. E.; Saulrieta, K.; Smith, Z.; Shah, M. V.; Radhakrishnan, M.; Philippakis, A. A.; Hu, Y. H.; De Masi, F.; Pacek, M.; Rolfs, A.; Murthy, T.; LaBaer, J.; Bulyk, M. L.. High-resolution DNA-binding specificity analysis of yeast transcription factors.. Genome Research (2009) Refereed Articles.