Open access to ‘The Origins of Cellular Architecture’

We have taken on one of the last uncharted fields in evolution: integrating evolutionary biology with cell biology. This sequel to The Origins of Genome Architecture brings evolutionary theory to bear on a diversity of observations on the functional and structural features of cells.

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Chung, C., Verheijen, B. M., Zhang, X., Huang, B., Coakley, A., McGann, E., Wade, E., Dinep-Schneider, O., LaGosh, J., Anagnostou, M.-E., Simpson, S., Thomas, K., Ernst, M., Rattray, A., Lynch, M., Kashlev, M., Benayoun, B. A., Li, Z., Strathern, J., … Vermulst, M. (2023). The fidelity of transcription in human cells. Proceedings of the National Academy of Sciences, 120(5).

Research article.


Kucukyildirim, S., Ozdemirel, H. O., & Lynch, M. (2022). Similar mutation rates but different mutation spectra in moderate and extremely halophilic archaea. G3 Genes|Genomes|Genetics, 13(3).

Journal article.

Lynch, M., Schavemaker, P. E., Licknack, T. J., Hao, Y., & Pezzano, A. (2022). Evolutionary Bioenergetics of ciliates. Journal of Eukaryotic Microbiology, 69(5).

Review article.

Lynch, M., Trickovic, B., & Kempes, C. P. (2022). Evolutionary scaling of maximum growth rate with organism size. Scientific Reports, 12(1).

Journal article.

Schavemaker, P. E., & Lynch, M. (2022). Flagellar energy costs across the Tree of Life. eLife, 11.

Research article.

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