Publications

Our team’s XFEL-related articles are listed below..

2023

Schmidt, M.; Malla, T. N.; Zielinski, K.; Aldama, L.; Bajt, S.; Feliz, D.; Hayes, B.; Hunter, M.; Kupitz, C.; Lisova, S.; Knoska, J.; Martin-Garcia, J.; Mariani, V.; Pandey, S.; Poudyal, I.; Sierra, R.; Tolstikova, A.; Yefanov, O.; Yoon, C. H.; Ourmazd, A.; Fromme, P.; Schwander, P.; Barty, A.; Chapman, H.; Stojkovic, E.; Batyuk, A.; Boutet, S.; Phillips, G.; Pollack, L., Heterogeneity in the M. tuberculosis beta-Lactamase Inhibition by Sulbactam. Res Sq 2023.

Jernigan, R. J.; Logeswaran, D.; Doppler, D.; Nagaratnam, N.; Sonker, M.; Yang, J. H.; Ketawala, G.; Martin-Garcia, J. M.; Shelby, M. L.; Grant, T. D.; Mariani, V.; Tolstikova, A.; Sheikh, M. Z.; Yung, M. C.; Coleman, M. A.; Zaare, S.; Kaschner, E. K.; Rabbani, M. T.; Nazari, R.; Zacks, M. A.; Hayes, B.; Sierra, R. G.; Hunter, M. S.; Lisova, S.; Batyuk, A.; Kupitz, C.; Boutet, S.; Hansen, D. T.; Kirian, R. A.; Schmidt, M.; Fromme, R.; Frank, M.; Ros, A.; Chen, J. J.; Botha, S.; Fromme, P., Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser. Structure 2023, 31 (2), 138-151 e5.

2022

Sulbactam Tek Narsingh Malla, Kara Zielinski, Luis Aldama, Sasa Bajt, Denisse Feliz, Brendon Hayes, Mark Hunter, Christopher Kupitz, Stella Lisova, Juraj Knoska, Jose Martin-Garcia, Valerio Mariani, Suraj Pandey, Ishwor Poudyal, Raymond G. Sierra, Alexandra Tolstikova, Oleksandr Yefanov, Chung Hong Yoon, Abbas Ourmazd, Petra Fromme, Peter Schwander, Anton Barty, Henry N. Chapman, Emina A. Stojkovic, Alex Batyuk, Sébastien Boutet, George N. Phillips Jr., Lois Pollack, Marius Schmidt (2022)“Heterogeneity in the M. tuberculosis β-lactamase inhibition by Sulbactam“ bioRxiv 2022.12.06.519319

Michael F. Brown, Thomas D. Grant, Suchithranga M.D.C. Perera, Alan Grossfield, Petra Fromme, Richard A. Kirian, et al. (2022). ” Functional dynamics of G-protein-coupled receptor shown by femtosecond X-ray scattering” Biophysical Journal 2022 Vol 121, Issue 3, Sup 1, 193A

C.Swathi K. Menon, Konstantinos Karpos, Thomas D. Grant, Petra Fromme, Richard A. Kirian, Michael F. Brown, et al. (2022). ” Time-resolved functional expansion of visual rhodopsin detected by x-ray scattering” Biophysical Journal 2022 Vol 121, Issue 3, Sup 1, 285A-286A

M. Sonker, D. Doppler, A. Egatz-Gomez, S. Zaare, M. T. Rabbani, A. Manna, et al. (2022). “Electrically stimulated droplet injector for reduced sample consumption in serial crystallography” Biophys Rep (N Y) 2022 Vol. 2 Issue 4 Pages 100081

Doppler, D., M. T. Rabbani, R. Letrun, J. Cruz Villarreal, D. H. Kim, S. Gandhi, A. Egatz-Gomez, M. Sonker, J. Chen, F. H. M. Koua, J. Yang, M. Youssef, V. Mazalova, S. Bajt, M. L. Shelby, M. A. Coleman, M. O. Wiedorn, J. Knoska, S. Schon, T. Sato, M. S. Hunter, A. Hosseinizadeh, C. Kuptiz, R. Nazari, R. C. Alvarez, K. Karpos, S. Zaare, Z. Dobson, E. Discianno, S. Zhang, J. D. Zook, J. Bielecki, R. de Wijn, A. R. Round, P. Vagovic, M. Kloos, M. Vakili, G. K. Ketawala, N. E. Stander, T. L. Olson, K. Morin, J. Mondal, J. Nguyen, J. D. Meza-Aguilar, G. Kodis, S. Vaiana, J. M. Martin-Garcia, V. Mariani, P. Schwander, M. Schmidt, M. Messerschmidt, A. Ourmazd, N. Zatsepin, U. Weierstall, B. D. Bruce, A. P. Mancuso, T. Grant, A. Barty, H. N. Chapman, M. Frank, R. Fromme, J. C. H. Spence, S. Botha, P. Fromme, R. A. Kirian and A. Ros (2022). “Co-flow injection for serial crystallography at X-ray free-electron lasers.” J Appl Crystallogr 55(Pt 1): 1-13.

Khokhriakov, I., O. Merkulova, A. Nozik, P. Fromme and V. Mazalova (2022). “A novel solution for controlling hardware components of accelerators and beamlines.” J Synchrotron Radiat 29(Pt 3): 644-653.

Martin-Garcia, J. M., S. Botha, H. Hu, R. Jernigan, A. Castellvi, S. Lisova, F. Gil, B. Calisto, I. Crespo, S. Roy-Chowdhury, A. Grieco, G. Ketawala, U. Weierstall, J. Spence, P. Fromme, N. Zatsepin, D. R. Boer and X. Carpena (2022). “Serial macromolecular crystallography at ALBA Synchrotron Light Source.” J Synchrotron Radiat 29(Pt 3): 896-907.

Zhang, S., D. T. Hansen, J. M. Martin-Garcia, J. D. Zook, S. Pan, F. M. Craciunescu, J. C. Burnett, Jr. and P. Fromme (2022). “Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor.” Sci Rep 12(1): 11824.

2021

Burak Guzelturk, et al., Visualization of dynamic polaronic strain fields in hybrid lead halide perovskites, 20, 618-623 (2021), DOI :10.1038/s41563-020-00865-5

Gisriel, C., Fromme, P. and Martin-Garcia, J. M. (2021). “Methods for Crystallization and Structural Determination of M-T7 Protein from Myxoma Virus.” In Viruses as Therapeutics (pp. 125-162). Humana, New York, NY.

Grant, T. D., Perera, S. M., Salas-Estrada, L. A., Struts, A. V., Chawla, U., Fried, S. D., Weerasinghe, N., Karpos, K., Meza, D., Zatsepin, N. A. and Grossfield, A., (2021). “Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser.” Biophysical Journal, 120(3), p.133a.

Han, H., Round, E., Schubert, R., Gül, Y., Makroczyová, J., Meza, D., Heuser, P., Aepfelbacher, M., Barák, I., Betzel, C., Fromme, P., Kursula, I., Nissen, P., Tereschenko, E., Schulz, J., Uetrecht, C., Ulicny, J., Wilmanns, M., Hajdu, J., Lamzin, V. S. and Lorenzen, K. (2021). “The XBI BioLab for life science experiments at the European XFEL.” Journal of Applied Crystallography, 54(1).

Lucas, A.R., Gisriel, C., Fromme, P. and Martin-Garcia, J. M. (2021). “Methods for Crystallization and Structural Determination of M-T7 Protein from Myxoma Virus” (No. PUBDB-2021-04846). EMBL-User.

Menon, C. S. K., Karpos, K., Grant, T. D., Struts, A. V., Fried, S. D., Perera, S. M., Kosheleva, I. V., Salas-Estrada, L., Grossfield, A., Fromme, P., Kirian, R. A. and Brown, M. F. (2021). “Functional Expansion of G-Protein-Coupled Receptor Shown by Time-Resolved X-Ray Scattering.” Biophysical Journal, 120(3), p.132a.

Nagaratnam, N., Delker, S. L., Jernigan, R., Edwards, T. E., Snider, J., Thifault, D., Williams, D., Nannenga, B. L., Stofega, M., Sambucetti, L., Hsieh, J. J., Flint, A. J., Fromme, P. and Martin-Garcia, J. M. (2021). “Structural insights into the function of the catalytically active human Taspase1.” Structure, 29(8), pp.873-885.

Pandey, S., Calvey, G., Katz, A. M., Malla, T. N., Koua, F. H., Martin-Garcia, J. M., Poudyal, I., Yang, J. H., Vakili, M., Yefanov, O., Zielinski, K.A., Sasa, B., Awel, S., Doerner, K., Frank M., Gelisio, L., Jernigan, R., Kirkwood., H., Kloos, M., Koliyadu, J., Mariani., V., Miller, M. D., Mills, G., Nelson, G., Olmos Jr, J. L., Sadri, A., Sato, A., Tolstikova, A., Xu, W., Ourmazd, A., Spence, J. C. H., Schwander, P., Barty, A., Chapman, H. N., Fromme, P., Mancuso, A. P., Phillips Jr, G. N., Bean, R., Pollack, L. and Schmidt, M. (2021). “Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography.” IUCrJ, 8(6).

Teitelbaum, S. W., T. C. Henighan, H. Liu, M. P. Jiang, D. Zhu, M. Chollet, T. Sato, É. D. Murray, S. Fahy, S. O’Mahony, T.. P. Bailey, C. Uher, M. Trigo, and D. A. Reis. (2021) Measurements of nonequilibrium interatomic forces using time-domain x-ray scattering, Physical Review B 103 (18), L180101 (2021) DOI: 10.1103/PhysRevB.103.L180101

2020

Basu, S., Fromme, P. and Fromme, R. (2020). “Application of Hard‐X‐Ray Free‐Electron Lasers for Static and Dynamic Processes in Structural Biology.” Structural Biology in Drug Discovery: Methods, Techniques, and Practices, pp.633-647.

Brehm, G., Echelmeier, A., Coe, J., Conrad, C. E., Nelson, G., Villarreal, J. C., Weierstall, U., Spence, J., Köster, S., Fromme, P. and Ros, A. (2020). “Combined hydrodynamic mixer and gas dynamic virtual nozzle devices for serial femtosecond crystallography.” In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1495-1496). Chemical and Biological Microsystems Society.

Echelmeier, A., et. al. (2020). “Segmented flow generator for serial crystallography at the European X-ray free electron laser.” Nature Commun 11(1):  4511.

Graves, W., Fromme, P., Holl, M., Malin, L., Messerschmidt, M., Nanni, E., Sandhu, A., Tantawi, S., Tilton, S. and Spence, J. (2020). “The ASU Compact XFEL Project.” Bulletin of the American Physical Society. 

Grant, T. D., Perera, S. M., Salas-Estrada, L. A., Struts, A. V., Chawla, U., Xu, X., Fried, S. D., Weerasinghe, N., Mendez, D., Alvarez, R., Karpos, K., K., Lisova, S., Zaare, S., Nazari, R., Zatsepsin, N. A., Singharoy, A., Boutet, S., Carbajo. S., Hunter, M. S., Liang, M., Seaberg, M. D., Fromme, R., Fromme, P., Grossfield, A., Kirian, R. A., and Brown, M. F. (2020). “Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser.” Biophysical Journal, 118(3), p.365a.

Jernigan, R. J., Nagaratnam, N., Thifault, D., Delker, S., Zacks, M., Edwards, T., Sambucetti, L., Tong, L., Fromme, R., Schneider, J., Hsieh, J., Mroczkowski, B., Flint, A., Fromme, P. and Garcia, J. M. (2020). “New Structural Insights into the Function of the Active Full Length Human Taspase1: A Novel Anticancer Therapeutic Target.” Biophysical Journal, 118(3), p.42a.

Layton, J., Nagaratnam, N., Jernigan, R. J., Schneider, J., Flint, A., Mroczkowski, B., Fromme, P., Garcia, J. M. and Singharoy, A. (2020). “Molecular Dynamics Simulations for Improving Crystal Quality and Illuminating the Function of Taspase1: A Therapeutic Target.” Biophysical Journal, 118(3), p.507a.

Nagaratnam, N., Tang, Y., Botha, S., Saul, J., Li, C., Hu, H., Zaare, S., Hunter, M., Lowry, D., Weierstall, U., Zatsepin, N., Spence, J. C. H, Qiu, J., LaBaer, J., Fromme, P. and Martin-Garcia, J.M. (2020). “Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs.” Acta Crystallographica Section F: Structural Biology Communications, 76(6), pp.278-289.

Nass, K., et. al., (2020). “In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors”. Nature communications, 11(1), pp.1-13.

Pandey, S., et. al. (2020). “Time-resolved serial femtosecond crystallography at the European XFEL.” Nature methods, 17(1), pp.73-78.

Rajan Plumley, et al., Speckle correlation as a monitor of X-ray free-electron laser induced crystal lattice deformation, Journal of Synchrotron Radiation 27 (6) (2020).

Salas-Estrada, L. A., Grant, T. D., Perera, S. M., Struts, A. V., Chawla, U., Xu, X., Fried, S.D., Weerasinghe, N., Mendez, D., Alvarez, R., Karpos, K., Lisova, S., Zaare, S., Nazari, R., Zatsepsin, N. A., Singharoy, A., Boutet, S., Carbajo. S., Hunter, M. S., Liang, M., Seaberg, M. D., Fromme, R., Fromme, P., Kirian, R. A., Brown, M. F., and Grossfield, A. (2020). “Rhodopsin’s Ultra-Fast Activation Dynamics in Bilayer and Micelle Environments.” Biophysical Journal, 118(3), p.92a.

Tang, Y., Saul, J., Nagaratnam, N., Martin-Garcia, J. M., Fromme, P., Qiu, J. and LaBaer, J. (2020). “Construction of gateway-compatible baculovirus expression vectors for high-throughput protein expression and in vivo microcrystal screening.” Scientific Reports, 10(1), pp.1-15.

Zook, J., Shekhar, M., Hansen, D., Conrad, C., Grant, T., Gupta, C., White, T., Barty, A., Basu, S., Zhao, Y., Zatsepin, N., Ishchenko, A., Batyuk, A., Gati, C., Li, C., Galli, L., Coe, J., Hunter, M., Liang, M., Weierstall, U., Nelson, G., James, D., Stauch, B., Craciunescu, F., Thifault, D., Liu, W., Cherezov, V., Singharoy, A., and Fromme, P Electric Triggering for Enhanced Control of Droplet Generation.. (2020). “XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia.” Structure. 28 (5), 540-547

2019

I. Ishigami et al., Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase. Proc Natl Acad Sci U S A116, 3572-3577 (2019).

Echelmeier, A., Kim, D., Cruz Villarreal, J., Coe, J., Quintana, S., Brehm, G., Egatz-Gomez, A., Nazari, R., Sierra, R.G., Koglin, J.E., Batyuk, A., Hunter, M.S, Boutet, S, Zatsepin,A., Kirian, R.A. , Grant, T. D., Fromme, P and Ros, A. (2019).  “3D printed droplet generation devices for serial femtosecond crystallography enabled by surface coating.” Journal of Applied Crystallography, 52(5).

E.R. Shanblatt, Y. Sung, R. Gupta, B.J. Nelson, S. Leng, W.S. Graves, C.H. McCollough, ‘A forward model for propagation-based phase contrast x-ray imaging in parallel- and cone-beam geometry’ Optics Express (27), pp. 4504-4521

Gisriel, C., et. al. (2019) “Membrane protein megahertz crystallography at the European XFEL.” Nature Communications 10(1), 5021.

Graves, W., Chang, S., Dwyer, D., Fromme, P., Holl, M., Levin, B., Malin, L., Vincent, J., Spence, J., and Nanni, E. (2019) “Nanopatterned electron beams for temporal coherence and deterministic phase control of x-ray free-electron lasers.” (2019) arXiv preprint arXiv:1906.01525.

Ishigami, I., A. Lewis-Ballester, A. Echelmeier, G. Brehm, N. A. Zatsepin, T. D. Grant, J. D. Coe, S. Lisova, G. Nelson, S. Zhang, Z. F. Dobson, S. Boutet, R. G. Sierra, A. Batyuk, P. Fromme, R. Fromme, J. C. H. Spence, A. Ros, S. R. Yeh and D. L. Rousseau (2019). “Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase.” Proc Natl Acad Sci U S A 116(9): 3572-3577.

Jensen, S. C., B. Sullivan, D. A. Hartzler, J. M. Aguilar, S. Awel, S. Bajt, S. Basu, R. Bean, H. N. Chapman, C. Conrad, M. Frank, R. Fromme, J. M. Martin-Garcia, T. D. Grant, M. Heymann, M. S. Hunter, G. Ketawala, R. A. Kirian, J. Knoska, C. Kupitz, X. Li, M. Liang, S. Lisova, V. Mariani, V. Mazalova, M. Messerschmidt, M. Moran, G. Nelson, D. Oberthur, A. Schaffer, R. G. Sierra, N. Vaughn, U. Weierstall, M. O. Wiedorn, P. L. Xavier, J. H. Yang, O. Yefanov, N. A. Zatsepin, A. Aquila, P. Fromme, S. Boutet, G. T. Seidler and Y. Pushkar (2019). “X-ray Emission Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis.” J Phys Chem Lett 10(3): 441-446.

Martin-Garcia, J. M., L. Zhu, D. Mendez, M. Y. Lee, E. Chun, C. Li, H. Hu, G. Subramanian, D. Kissick, C. Ogata, R. Henning, A. Ishchenko, Z. Dobson, S. Zhang, U. Weierstall, J. C. H. Spence, P. Fromme, N. A. Zatsepin, R. F. Fischetti, V. Cherezov and W. Liu (2019). “High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source.” IUCrJ 6(Pt 3): 412-425.

Martin-Garcia, J., Spence, J. and Fromme, P. (2019). “Latest Advances on Serial Crystallography at XFELs and Synchrotron Sources.” Foundations of Crystallography. Acta Cryst, A75, a109.

Salas, L., Mendez, D., Meza-Aguilar, J.D., Perera, S.M., Singharoy, A., Struts, A.V., Zatsepin, N.A., Kirian, R.A., Grant, T.D., Fromme, P. and Brown, M.F. (2019). “Study of Ultra-Fast Rhodopsin Activation Dynamics with Molecular Dynamics Simulations.” Biophysical Journal, 116(3), 205a.

Stander, N., Fromme, P. and Zatsepin, N. (2019). “DatView: a graphical user interface for visualizing and querying large data sets in serial femtosecond crystallography.” Journal of Applied Crystallography, 52(6).

Yefanov, O., et al. (2019). “Evaluation of serial crystallographic structure determination within megahertz pulse trains.” Structural Dynamics, 6(6), p.064702.

Y Sun, et al., Compact hard x-ray split-delay system based on variable-gap channel-cut crystals. Optics Lett. 44, 10 2582 (2019).

2018

Electron Beam Optics for the ASU Compact XFEL, C Zheng, W Graves, M Holl, L Malin, and E Nanni, JACoW Publishing, 9th Int. Particle Accelerator Conf.(IPAC’18), Vancouver, BC, Canada, (2018)

Nanomodulated electron beams via electron diffraction and emittance exchange for coherent x-ray generation, EA Nanni, WS Graves, and DE Moncton, submitted to Phys. Rev. Lett. (2018) 014401

J. L. Olmos, Jr. et al., Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography. BMC Biol 16, 59 (2018).

Lan, T. Y., J. L. Wierman, M. W. Tate, H. T. Philipp, J. M. Martin-Garcia, L. Zhu, D. Kissick, P. Fromme, R. F. Fischetti, W. Liu, V. Elser and S. M. Gruner (2018). “Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source.” IUCrJ 5(Pt 5): 548-558.

Lee, D. B., J. M. Kim, J. H. Seok, J. H. Lee, J. D. Jo, J. Y. Mun, C. Conrad, J. Coe, G. Nelson, B. Hogue, T. A. White, N. Zatsepin, U. Weierstall, A. Barty, H. Chapman, P. Fromme, J. Spence, M. S. Chung, C. H. Oh and K. H. Kim (2018). “Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography.” Sci Rep 8(1): 2541.

Olmos, J. L., Jr., S. Pandey, J. M. Martin-Garcia, G. Calvey, A. Katz, J. Knoska, C. Kupitz, M. S. Hunter, M. Liang, D. Oberthuer, O. Yefanov, M. Wiedorn, M. Heyman, M. Holl, K. Pande, A. Barty, M. D. Miller, S. Stern, S. Roy-Chowdhury, J. Coe, N. Nagaratnam, J. Zook, J. Verburgt, T. Norwood, I. Poudyal, D. Xu, J. Koglin, M. H. Seaberg, Y. Zhao, S. Bajt, T. Grant, V. Mariani, G. Nelson, G. Subramanian, E. Bae, R. Fromme, R. Fung, P. Schwander, M. Frank, T. A. White, U. Weierstall, N. Zatsepin, J. Spence, P. Fromme, H. N. Chapman, L. Pollack, L. Tremblay, A. Ourmazd, G. N. Phillips, Jr. and M. Schmidt (2018). “Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography.” BMC Biol 16(1): 59.

Pande, K., J. J. Donatelli, E. Malmerberg, L. Foucar, B. K. Poon, M. Sutter, S. Botha, S. Basu, R. Bruce Doak, K. Dorner, S. W. Epp, L. Englert, R. Fromme, E. Hartmann, R. Hartmann, G. Hauser, J. Hattne, A. Hosseinizadeh, S. Kassemeyer, L. Lomb, S. F. C. Montero, A. Menzel, D. Rolles, A. Rudenko, M. M. Seibert, R. G. Sierra, P. Schwander, A. Ourmazd, P. Fromme, N. K. Sauter, M. Bogan, J. Bozek, C. Bostedt, I. Schlichting, C. A. Kerfeld and P. H. Zwart (2018). “Free-electron laser data for multiple-particle fluctuation scattering analysis.” Sci Data 5: 180201.

SW Teitelbaum, et al., Direct measurement of anharmonic decay channels of a coherent phonon. Phys. Rev. Lett. 121, 125901 (2018).

SW Teitelbaum, et al., Frequency-selective excitation of high-wavevector phonons. Appl. Phys. Lett. 113, 17, 171901 (2018)

Wiedorn, M. O., S. Awel, A. J. Morgan, K. Ayyer, Y. Gevorkov, H. Fleckenstein, N. Roth, L. Adriano, R. Bean, K. R. Beyerlein, J. Chen, J. Coe, F. Cruz-Mazo, T. Ekeberg, R. Graceffa, M. Heymann, D. A. Horke, J. Knoska, V. Mariani, R. Nazari, D. Oberthur, A. K. Samanta, R. G. Sierra, C. A. Stan, O. Yefanov, D. Rompotis, J. Correa, B. Erk, R. Treusch, J. Schulz, B. G. Hogue, A. M. Ganan-Calvo, P. Fromme, J. Kupper, A. V. Rode, S. Bajt, R. A. Kirian and H. N. Chapman (2018). “Rapid sample delivery for megahertz serial crystallography at X-ray FELs.” IUCrJ 5(Pt 5): 574-584.

Wiedorn, M. O., D. et al. (2018). “Megahertz serial crystallography.” Nat Commun 9(1): 4025.

2017

Design of an x-band photoinjector operating at 1 khz, WS Graves, AC Goodrich, MR Holl, NJ O’Brien, V Bharadwaj, P Borchard, Valery Dolgashev, EA Nanni, 8th Int. Particle Accelerator Conf.(IPAC’17), Copenhagen, Denmark, (2017)

Fromme, P. and J. C. H. Spence, Split-Second Reactions. Sci Am 316, 62-67 (2017).

Gati C, Oberthuer D, Yefanov O, Bunker RD, Stellato F, Chiu E, Yeh SM, Aquila A, Basu S, Bean R, Beyerlein KR, Botha S, Boutet S, DePonte DP, Doak RB, Fromme R, Galli L, Grotjohann I, James DR, Kupitz C, Lomb L, Messerschmidt M, Nass K, Rendek K, Shoeman RL, Wang D, Weierstall U, White TA, Williams GJ, Zatsepin NA, Fromme P, Spence JC, Goldie KN, Jehle JA, Metcalf P, Barty A, and Chapman HN. (2017) Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser. Proc Natl Acad Sci U S A 114: 2247-2252

Ishigami,I. et al., Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Proc Natl Acad Sci U S A 114, 8011-8016 (2017).

Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, Hartmann E, Jafarpour A, Foucar LM, Barty A, Chapman H, Liang M, Menzel A, Wang F, Basu S, Fromme R, Doak RB, Fromme P, Weierstall U, Huang MH, Spence JC, Schlichting I, Hogue BG, and Liu H. (2017) Diffraction data of core-shell nanoparticles from an X-ray free electron laser. Sci Data 4: 170048, 2017.

Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A, Nagaratnam N, Roy-Chowdhury S, Coe J, Subramanian G, Schaffer A, James D, Ketwala G, Venugopalan N, Xu S, Corcoran S, Ferguson D, Weierstall U, Spence JCH, Cherezov V, Fromme P, Fischetti RF, and Liu W. (2017)  Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCRJ 4: 439-454

Reddy HKN, Yoon CH, Aquila A, Awel S, Ayyer K, Barty A, Berntsen P, Bielecki J, Bobkov S, Bucher M, Carini GA, Carron S, Chapman H, Daurer B, DeMirci H, Ekeberg T, Fromme P, Hajdu J, Hanke MF, Hart P, Hogue BG, Hosseinizadeh A, Kim Y, Kirian RA, Kurta RP, Larsson DSD, Duane Loh N, Maia F, Mancuso AP, Muhlig K, Munke A, Nam D, Nettelblad C, Ourmazd A, Rose M, Schwander P, Seibert M, Sellberg JA, Song C, Spence JCH, Svenda M, Van der Schot G, Vartanyants IA, Williams GJ, and Xavier PL. (2017) Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source. Sci Data 4: 170079, 2017.

Kurta, Ruslan P., Donatelli, Jeffrey J., Yoon, Chun Hong, Berntsen, Peter, Bielecki, Johan, Daurer, Benedikt J., DeMirci, Hasan, Fromme, Petra, Hantke, Max Felix, Maia, Filipe R. N. C., Munke, Anna, Nettelblad, Carl, Pande, Kanupriya, Reddy, Hemanth, K. N., Sellberg, Jonas A., Sierra, Raymond G., Svenda, Martin, van der Schot, Gijs, Vartanyants, Ivan A., Williams, Garth J., Xavier, P. Lourdu, Aquila, Andrew, Zwart, Peter H., and Mancuso, Adrian P.  (2017) Correlations in scattered x-ray laser pulses reveal nanoscale structural features of viruses.  Physical Review Letters, Vol 119.

Kupitz, C., Olmos, J.L., Jr., Holl, M., Tremblay, L., Pande, K., Pandey, S., Oberthur, D., Hunter, M., Liang, M., Aquila, A., Tenboer, J., Calvey, G., Katz, A., Chen, Y., Wiedorn, M.O., Knoska, J., Meents, A., Majriani, V., Norwood, T., Poudyal, I., Grant, T., Miller, M.D., Xu, W., Tolstikova, A., Morgan, A., Metz, M., Martin-Garcia, J.M., Zook, J.D., Roy-Chowdhury, S., Coe, J., Nagaratnam, N., Meza, D., Fromme, R., Basu, S., Frank, M., White, T., Barty, A., Bajt, S., Yefanov, O., Chapman, H.N., Zatsepin, N., Nelson, G., Weierstall, U., Spence, J., Schwander, P., Pollack, L., Fromme, P., Ourmazd, A., Phillips, G.N., Jr., Schmidt, M. (2017) Structural enzymology using X-ray free electron lasers. Struct Dyn, 4(4), 044003.

Stagno, J.R., Liu, Y., Bhandari, Y.R., Conrad, C.E., Panja, S., Swain, M., Fan, L., Nelson, G., Li, C., Wendel, D.R., White, T.A., Coe, J.D., Wiedorn, M.O., Knoska, J., Oberthuer, D., Tuckey, R.A., Yu, P., Dyba, M., Tarasov, S.G., Weierstall, U., Grant, T.D., Schwieters, C.D., Zhang, J., Ferre-D’Amare, A.R., Fromme, P., Draper, D.E., Liang, M., Hunter, M.S., Boutet, S., Tan, K., Zuo, X., Ji, X., Barty, A., Zatsepin, N.A., Chapman, H.N., Spence, J.C., Woodson, S.A., Wang, Y.X. (2017) Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541(7636), 242-246.

P. Fromme, J. C. H. Spence, Split-Second Reactions. Sci Am 316, 62-67 (2017).

Y. Sung, R. Gupta, B. Nelson S. Leng C.H. McCollough, and W.S. Graves “Phase contrast imaging with a compact x-ray light source: System design”, Journal of Medical Imaging 4(4), 043503 (Oct-Dec 2017)

C. Zhang, W.S. Graves, L.E. Malin, J.C.H Spence, R.K. Li, E.A. Nanni, X. Shen, S.P. Weathersby, J. Yang, D. Cesar, J.Maxson, P. Musumeci and A. Urbanowicz, “Experiments in Electron Beam Nanopatterning”, Proceedings of 38th International Free Electron Laser Conference, TUP038, Santa Fe, NM (2017)

W. S. Graves, J.P.J. Chen, P. Fromme, M.R. Holl, R. Kirian, L.E. Malin, K.E. Schmidt, J.C.H. Spence, M. Underhill, U. Weierstall, N.A. Zatsepin, C. Zhang, P.D. Brown, K.-H. Hong, D.E. Moncton, E.A. Nanni, C. Limborg-Deprey,, “ASU compact XFEL”, Proceedings of 2017 International FEL Conference, Santa Fe, NM, TUB03 (2017)

L. Malin, W.S. Graves, J.C.H. Spence, C. Zhang, R. Li, C. Limborg, E.A. Nanni, X. Shen, and S. Weathersby, “Comparison of theory, simulation, and experiment for dynamical extinction of relativistic electron beams”, Proceedings of Int. Particle Accel. Conf, Copenhagen, Denmark, THPAB088 (2017)

C. Zhang, W.S. Graves, L.E. Malin, J.C.H Spence, C. Limborg, E.A. Nanni, D. Cesar, J. Maxson, A. Urbanowicz, and P. Musumeci, “Imaging the Spatial Modulation of a Relativistic Electron Beam”, Proc. of International Particle Accel. Conf, Copenhagen, Denmark, MOPAB150 (2017)

W. S. Graves, A.C. Goodrich, M.R. Holl, N.J. O’Brien, V. Bharadwaj, P. Borchard, P.D. Brown, V. Dolgashev, E.A. Nanni, “Design of an x-band photoinjector operating at 1 khz,” Proc. of International Particle Accel. Conf, Copenhagen, Denmark, TUPAB139 (2017)

W.S. Graves (co-author among 45 others), Report of the DOE-BES workshop on Future Electron Sources

2016

Abdallah, B.G., Roy-Chowdhury, S., Fromme, R., Fromme, P., Ros, A. (2016) Protein Crystallization in an Actuated Microfluidic Nanowell Device. Crystal Growth & Design, 16(4), 2074-2082.

Ayyer, K., Yefanov, O.M., Oberthur, D., Roy-Chowdhury, S., Galli, L., Mariani, V., Basu, S., Coe, J., Conrad, C.E., Fromme, R., Schaffer, A., Droner, K., James, D., Kupitz, C., Metz, M., Nelson, G., Xavier, P.L., Beyerlein, K.R., Schmidt, M., Sarrou, I., Spence, J.C.H., Weierstall, U., White, T.A., Yang, J.H., Zhao, Y., Liang, M.N., Aquila, A., Hunter, M.S., Robinson, J.S., Koglin, J.E., Boutet, S., Fromme, P., Barty, A., Chapman, H.N. (2016) Macromolecular diffractive imaging using imperfect crystals. Nature, 530(7589), 202-+.

Coe, J. and Fromme, P. (2016) Serial Femtosecond Crystallography Opens New Avenues for Structural Biology. Protein and Peptide Letters, 23(3), 255-272.

Dorner, K., Martin-Garcia, J.M., Kupitz, C., Gong, Z., Mallet, T.C., Chen, L.Q., Wachter, R.M., Fromme, P. (2016) Characterization of Protein Nanocrystals Based on the Reversibility of Crystallization. Crystal Growth & Design, 16(7), 3838-3845.

Dow, X.Y., Dettmar, C.M., DeWalt, E.L., Newman, J.A., Dow, A.R., Roy-Chowdhury, S., Coe, J.D., Kupitz, C., Fromme, P., Simpson, G.J. (2016) Second harmonic generation correlation spectroscopy for characterizing translationally diffusing protein nanocrystals. Acta Crystallographica Section D-Structural Biology, 72, 849-859.

Edlund, P., Takala, H., Claesson, E., Henry, L., Dods, R., Lehtivuori, H., Panman, M., Pande, K., White, T., Nakane, T., Berntsson, O., Gustavsson, E., Bath, P., Modi, V., Roy-Chowdhury, S., Zook, J., Berntsen, P., Pandey, S., Poudyal, I., Tenboer, J., Kupitz, C., Barty, A., Fromme, P., Koralek, J.D., Tanaka, T., Spence, J., Liang, M.L., Hunter, M.S., Boutet, S., Nango, E., Moffat, K., Groenhof, G., Ihalainen, J., Stojkovic, E.A., Schmidt, M., Westenhoff, S. (2016) The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography. Scientific Reports, 6.

Kärtner, F.X., Ahr, F., Calendron, A.L., Cankaya, H., Carbajo, S., Chang, G., Cirmi, G., Dorner, K., Dorda, U., Fallahi, A., Hartin, A., Hemmer, M., Hobbs, R., Hua, Y., Huang, W.R., Letrun, R., Maths, N., Mazalova, V., Mucke, O.D., Nanni, E., Putnam, W., Ravi, K., Reichert, F., Sarrou, I., Wu, X., Yahaghi, A., Ye, H., Zapata, L., Zhang, D., Zhou, C., Miller, R.J.D., Berggren, K.K., Graafsma, H., Meents, A., Assmann, R.W., Chapman, H.N., Fromme, P. (2016) AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment, 829, 24-29.

Martin-Garcia, J.M., Conrad, C.E., Coe, J., Roy-Chowdhury, S., Fromme, P. (2016) Serial femtosecond crystallography: A revolution in structural biology. Archives of Biochemistry and Biophysics, 602, 32-47.

Munke, A., Andreasson, J., Aquila, A., Awel, S., Ayyer, K., Barty, A., Bean, R.J., Berntsen, P., Bielecki, J., Boutet, S., Bucher, M., Chapman, H.N., Daurer, B.J., DeMirci, H., Elser, V., Fromme, P., Hajdu, J., Hantke, M.F., Higashiura, A., Hogue, B.G., Hosseinizadeh, A., Kim, Y., Kirian, R.A., Reddy, H.K.N., Lan, T.Y., Larsson, D.S.D., Liu, H.G., Loh, N.D., Maia, F.R.N.C., Mancuso, A.P., Muhlig, K., Nakagawa, A., Nam, D., Nelson, G., Nettelblad, C., Okamoto, K., Ourmazd, A., Rose, M., van der Schot, G., Schwander, P., Seibert, M.M., Sellberg, J.A., Sierra, R.G., Song, C.Y., Svenda, M., Timneanu, N., Vartanyants, I.A., Westphal, D., Wiedorn, M.O., Williams, G.J., Xavier, P.L., Yoon, C.H., Zook, J. (2016) Data Descriptor: Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source. Scientific Data, 3.

Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W.T., Conrad, C., Coe, J., Bean, R., Zhao, Y., Bath, P., Dods, R., Harimoorthy, R., Beyerlein, K.R., Rheinberger, J., James, D., DePonte, D., Li, C.F., Sala, L., Williams, G.J., Hunter, M.S., Koglin, J.E., Berntsen, P., Nango, E., Iwata, S., Chapman, H.N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T.A., Weierstall, U., Spence, J., Neutze, R., Schertler, G., Standfuss, J. (2016) Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography. Nature Communications, 7. 

Pande, K., Hutchison, C.D.M., Groenhof, G., Aquila, A., Robinson, J.S., Tenboer, J., Basu, S., Boutet, S., DePonte, D.P., Liang, M.N., White, T.A., Zatsepin, N.A., Yefanov, O., Morozov, D., Oberthuer, D., Gati, C., Subramanian, G., James, D., Zhao, Y., Koralek, J., Brayshaw, J., Kupitz, C., Conrad, C., Roy-Chowdhury, S., Coe, J.D., Metz, M., Xavier, P.L., Grant, T.D., Koglin, J.E., Ketawala, G., Fromme, R., Srajer, V., Henning, R., Spence, J.C.H., Ourmazd, A., Schwander, P., Weierstall, U., Frank, M., Fromme, P., Barty, A., Chapman, H.N., Moffat, K., van Thor, J.J., Schmidt, M. (2016) Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein. Science, 352(6286), 725-729.

Zhou, X.E., Gao, X., Barty, A., Kang, Y.Y., He, Y.Z., Liu, W., Ishchenko, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q.P., de Waal, P.W., Suino-Powell, K.M., Boutet, S., Williams, G.J., Wang, M.T., Li, D.F., Caffrey, M., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E. (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Scientific Data, 3.

Measurements Of Transmitted Electron Beam Extinction Through Si Crystal Membranes, E Nanni, U Weierstall, R Li, W Graves, R Kirian, X Shen, J Spence, C Limborg, S Weathersby (2016) 978-3-95450-147-2

X. E. Zhou et al., X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Sci Data 3, 160021 (2016).

K. Pande et al., Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein. Science 352, 725-729 (2016).

Munke et al., Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source. Sci Data 3, 160064 (2016).

F. X. Kartner et al., AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy. Nucl Instrum Methods Phys Res A 829, 24-29 (2016).

P. Edlund et al., The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography. Sci Rep 6, 35279 (2016).

2015

Li D, Stansfeld PJ, Sansom MSP, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Seibert MM, Caffrey M Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications  2015 (6), e10140

Fromme, P XFELs open a new era in structural chemical biology, Nature Chemical Biology 2015 (11), p. 895-899

Conrad CE, Basu S, James D, Wang DJ, Schaffer A, Roy-Chowdhury S, Zatsepin NA, Aquila A, Coe J, Gati C, Hunter MS, Koglin JE, Kupitz C, Nelson G, Subramanian G, White TA, Zhao Y, Zook J, Boutet S, Cherezov V, Spence JCH, Fromme R, Weierstall U, Fromme P A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ 2015 2: p. 421-430

Kang YY, Zhou XE, Gao X, He YZ, Liu W, Ishchenko A, Barty A, Sathish D, Yefanov O, Han GW, Xu QP, de Waal PW, Ke JY, Tan MHE, Zhang CH, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma JM, Zhi XY, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang DJ, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu HG, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan MJ, Yang HY, Li J, Wang MT, Zheng Z, Li DF, Howe N, Zhao YM, Standfuss J, Diederichs K, Dong YH, Potter CS, Carragher B, Caffrey M, Jiang HL, Chapman HN, Spence JCH, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 2015, 523: p. 561-567.

Zhang, H., H. Unal, C. Gati, Gye W. Han, W. Liu, Nadia A. Zatsepin, D. James, D. Wang, G. Nelson, U. Weierstall, Michael R. Sawaya, Q. Xu, M. Messerschmidt, Garth J. Williams, S. Boutet, Oleksandr M. Yefanov, Thomas A. White, C. Wang, A. Ishchenko, Kalyan C. Tirupula, R. Desnoyer, J. Coe, Chelsie E. Conrad, P. Fromme, Raymond C. Stevens, V. Katritch, Sadashiva S. Karnik, and V. Cherezov, Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell, 2015. 161(4): p. 833-844.

Fromme R, Ishchenko A, Metz M, Chowdhury SR, Basu S, Boutet S, Fromme P, White TA, Barty A, Spence JCH, Weierstall U, Liu W, Cherezov V (2015) Serial femtosecond crystallography of soluble proteins in lipidic cubic phase. IUCrJ 2015 (2): p. 545-551

Abdallah BG, Zatsepin NA, Roy-Chowdhury S, Coe J, Conrad CE, Dorner K, Sierra RG, Stevenson HP, Camacho-Alanis F, Grant TD, Nelson G, James D, Calero G, Wachter RM, Spence JCH, Weierstall U, Fromme P, Ros A (2015) Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction. Structural dynamics 2015 (2) 4: e041719

Fenalti, G., N.A. Zatsepin, C. Betti, P. Giguere, G.W. Han, A. Ishchenko, W. Liu, K. Guillemyn, H. Zhang, D. James, D. Wang, U. Weierstall, J.C.H. Spence, S. Boutet, M. Messerschmidt, G.J. Williams, C. Gati, O.M. Yefanov, T.A. White, D. Oberthuer, M. Metz, C.H. Yoon, A. Barty, H.N. Chapman, S. Basu, J. Coe, C.E. Conrad, R. Fromme, P. Fromme, D. Tourwé, P.W. Schiller, B.L. Roth, S. Ballet, V. Katritch, R.C. Stevens, and V. Cherezov, Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nat Struct Mol Biol, 2015. 22(3): p. 265-268.

Abdallah, B.G., S. Roy-Chowdhury, J. Coe, P. Fromme, and A. Ros, High Throughput Protein Nanocrystal Fractionation in a Microfluidic Sorter. Analytical Chemistry, 2015. 87(8): p. 4159-4167.

Nano-modulated electron beams via electron diffraction and emittance exchange for coherent x-ray generation, E.A. Nanni, W. S. Graves, and D.E. Moncton submitted to Phys. Rev. Lett. (2015), arXiv:1506.07053

Aberration Corrected Emittance Exchange, E.A. Nanni and W. S. Graves, Phys. Rev. ST Accel. Beams 18, 084401 (2015)

H. Zhang et al., Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. Cell 161, 833-844 (2015).

Y. Kang et al., Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523, 561-567 (2015).

P. Fromme, XFELs open a new era in structural chemical biology. Nat Chem Biol 11, 895-899 (2015).

2014

High-density Au nanorod optical field-emitter arrays, RG Hobbs, Y Yang, PD Keathley, ME Swanwick, LF Velásquez-Garcíia, FX Kärtner, WS Graves, and KK Berggren, Nanotechnology 25, 465304 (2014)

Compact x-ray source based on burst-mode inverse Compton scattering at 100 kHz, W. S. Graves, J. Bessuille, P. Brown, S. Carbajo, V. Dolgashev, K.-H. Hong, E. Ihloff,  B. Khaykovich, H. Lin, K. Murari, E. A. Nanni, G. Resta, S. Tantawi, L.E. Zapata, F.X. Kärtner, and D.E. Moncton, Phys. Rev. ST Accel. Beams 17, 120701 (2014)

High-Yield, Ultrafast, Surface Plasmon-Enhanced, Au Nanorod Optical Field Electron Emitter Arrays, R. G. Hobbs, Y. Yang, A. Fallahi, P. D. Keathley, E. De Leo, F. X. Kärtner, W. S. Graves, and K. Berggren, ACS Nano 8, 11474-11482 (2014)

J. Tenboer et al., Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science 346, 1242-1246 (2014).

C. Kupitz et al., Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature 513, 261-265 (2014).

D. Arnlund et al., Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nat Methods 11, 923-926 (2014).

Weierstall, U., D. James, C. Wang, T.A. White, D. Wang, W. Liu, J.C.H. Spence, R. Bruce Doak, G. Nelson, P. Fromme, R. Fromme, I. Grotjohann, C. Kupitz, N.A. Zatsepin, H. Liu, S. Basu, D. Wacker, G. Won Han, V. Katritch, S. Boutet, M. Messerschmidt, G.J. Williams, J.E. Koglin, M. Marvin Seibert, M. Klinker, C. Gati, R.L. Shoeman, A. Barty, H.N. Chapman, R.A. Kirian, K.R. Beyerlein, R.C. Stevens, D. Li, S.T.A. Shah, N. Howe, M. Caffrey, and V. Cherezov, Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nature Communications, 2014. 5: p. 3309.

Tenboer, J., S. Basu, N. Zatsepin, K. Pande, D. Milathianaki, M. Frank, M. Hunter, S. Boutet, G.J. Williams, J.E. Koglin, D. Oberthuer, M. Heymann, C. Kupitz, C. Conrad, J. Coe, S. Roy-Chowdhury, U. Weierstall, D. James, D. Wang, T. Grant, A. Barty, O. Yefanov, J. Scales, C. Gati, C. Seuring, V. Srajer, R. Henning, P. Schwander, R. Fromme, A. Ourmazd, K. Moffat, J.J. Van Thor, J.C.H. Spence, P. Fromme, H.N. Chapman, and M. Schmidt, Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science, 2014. 346(6214): p. 1242-1246.

Kupitz, C., I. Grotjohann, C.E. Conrad, S. Roy-Chowdhury, R. Fromme, and P. Fromme, Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system. Philosophical Transactions of the Royal Society B: Biological Sciences, 2014. 369(1647): p. 20130316.

Kupitz, C., S. Basu, I. Grotjohann, R. Fromme, N.A. Zatsepin, K.N. Rendek, M.S. Hunter, R.L. Shoeman, T.A. White, D. Wang, D. James, J.-H. Yang, D.E. Cobb, B. Reeder, R.G. Sierra, H. Liu, A. Barty, A.L. Aquila, D. Deponte, R.A. Kirian, S. Bari, J.J. Bergkamp, K.R. Beyerlein, M.J. Bogan, C. Caleman, T.-C. Chao, C.E. Conrad, K.M. Davis, H. Fleckenstein, L. Galli, S.P. Hau-Riege, S. Kassemeyer, H. Laksmono, M. Liang, L. Lomb, S. Marchesini, A.V. Martin, M. Messerschmidt, D. Milathianaki, K. Nass, A. Ros, S. Roy-Chowdhury, K. Schmidt, M. Seibert, J. Steinbrener, F. Stellato, L. Yan, C. Yoon, T.A. Moore, A.L. Moore, Y. Pushkar, G.J. Williams, S. Boutet, R.B. Doak, U. Weierstall, M. Frank, H.N. Chapman, J.C.H. Spence, and P. Fromme, Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature, 2014. 513(7517): p. 261-265.

Fromme, P., Leading-edge lasers. Nature, 2014. 505(7485): p. 620-621.

Arnlund, D., L.C. Johansson, C. Wickstrand, A. Barty, G.J. Williams, E. Malmerberg, J. Davidsson, D. Milathianaki, D.P. DePonte, R.L. Shoeman, D. Wang, D. James, G. Katona, S. Westenhoff, T.A. White, A. Aquila, S. Bari, P. Berntsen, M. Bogan, T.B. van Driel, R.B. Doak, K.S. Kjaer, M. Frank, R. Fromme, I. Grotjohann, R. Henning, M.S. Hunter, R.A. Kirian, I. Kosheleva, C. Kupitz, M. Liang, A.V. Martin, M.M. Nielsen, M. Messerschmidt, M.M. Seibert, J. Sjohamn, F. Stellato, U. Weierstall, N.A. Zatsepin, J.C.H. Spence, P. Fromme, I. Schlichting, S. Boutet, G. Groenhof, H.N. Chapman, and R. Neutze, Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nat Meth, 2014. 11(9): p. 923-926.

2013

L. Redecke et al., Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Science339, 227-230 (2013).

W. Liu et al., Serial femtosecond crystallography of G protein-coupled receptors. Science 342, 1521-1524 (2013).

Rendek, K.N., R. Fromme, I. Grotjohann, and P. Fromme, Crystallization of a self-assembled three-dimensional DNA nanostructure. Acta Crystallographica Section F, 2013. 69(2): p. 141-146.

Abdallah, B.G., T.-C. Chao, C. Kupitz, P. Fromme, and A. Ros, Dielectrophoretic Sorting of Membrane Protein Nanocrystals. ACS Nano, 2013. 7(10): p. 9129-9137.

Redecke, L., K. Nass, D.P. DePonte, T.A. White, D. Rehders, A. Barty, F. Stellato, M. Liang, T.R.M. Barends, S. Boutet, G.J. Williams, M. Messerschmidt, M.M. Seibert, A. Aquila, D. Arnlund, S. Bajt, T. Barth, M.J. Bogan, C. Caleman, T.-C. Chao, R.B. Doak, H. Fleckenstein, M. Frank, R. Fromme, L. Galli, I. Grotjohann, M.S. Hunter, L.C. Johansson, S. Kassemeyer, G. Katona, R.A. Kirian, R. Koopmann, C. Kupitz, L. Lomb, A.V. Martin, S. Mogk, R. Neutze, R.L. Shoeman, J. Steinbrener, N. Timneanu, D. Wang, U. Weierstall, N.A. Zatsepin, J.C.H. Spence, P. Fromme, I. Schlichting, M. Duszenko, C. Betzel, and H.N. Chapman, Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser. Science, 2013. 339(6116): p. 227-230.

Liu, W., D. Wacker, C. Gati, G.W. Han, D. James, D. Wang, G. Nelson, U. Weierstall, V. Katritch, A. Barty, N.A. Zatsepin, D. Li, M. Messerschmidt, S. Boutet, G.J. Williams, J.E. Koglin, M.M. Seibert, C. Wang, S.T.A. Shah, S. Basu, R. Fromme, C. Kupitz, K.N. Rendek, I. Grotjohann, P. Fromme, R.A. Kirian, K.R. Beyerlein, T.A. White, H.N. Chapman, M. Caffrey, J.C.H. Spence, R.C. Stevens, and V. Cherezov, Serial Femtosecond Crystallography of G Protein–Coupled Receptors. Science, 2013. 342(6165): p. 1521-1524.

Johansson, L.C., D. Arnlund, G. Katona, T.A. White, A. Barty, D.P. DePonte, R.L. Shoeman, C. Wickstrand, A. Sharma, G.J. Williams, A. Aquila, M.J. Bogan, C. Caleman, J. Davidsson, R.B. Doak, M. Frank, R. Fromme, L. Galli, I. Grotjohann, M.S. Hunter, S. Kassemeyer, R.A. Kirian, C. Kupitz, M. Liang, L. Lomb, E. Malmerberg, A.V. Martin, M. Messerschmidt, K. Nass, L. Redecke, M.M. Seibert, J. Sjöhamn, J. Steinbrener, F. Stellato, D. Wang, W.Y. Wahlgren, U. Weierstall, S. Westenhoff, N.A. Zatsepin, S. Boutet, J.C.H. Spence, I. Schlichting, H.N. Chapman, P. Fromme, and R. Neutze, Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. Nature Communications, 2013. 4: p. 2911.

Abdallah, B.G., C. Kupitz, P. Fromme, and A. Ros, Crystallization of the Large Membrane Protein Complex Photosystem I in a Microfluidic Channel. ACS Nano, 2013. 7(12): p. 10534-10543.

2012

Intense Superradiant X Rays from A Compact Source using a Nanocathode Array and Emittance Exchange, W.S. Graves, F.X. Kaertner, and D.E. Moncton, Phys. Rev. Lett 108, 263904 (2012)

R. Koopmann et al., In vivo protein crystallization opens new routes in structural biology. Nat Methods 9, 259-262 (2012).

S. Boutet et al., High-resolution protein structure determination by serial femtosecond crystallography. Science 337, 362-364 (2012).

A. Aquila et al., Time-resolved protein nanocrystallography using an X-ray free-electron laser. Opt Express 20, 2706-2716 (2012).

Koopmann, R., K. Cupelli, L. Redecke, K. Nass, D.P. DePonte, T.A. White, F. Stellato, D. Rehders, M. Liang, J. Andreasson, A. Aquila, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, S. Boutet, J.D. Bozek, C. Caleman, N. Coppola, J. Davidsson, R.B. Doak, T. Ekeberg, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, A. Hartmann, R. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, S. Kassemeyer, R.A. Kirian, L. Lomb, F.R.N.C. Maia, N. Kimmel, A.V. Martin, M. Messerschmidt, C. Reich, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, J. Schulz, M.M. Seibert, R.L. Shoeman, R.G. Sierra, H. Soltau, S. Stern, L. Struder, N. Timneanu, J. Ullrich, X. Wang, G. Weidenspointner, U. Weierstall, G.J. Williams, C.B. Wunderer, P. Fromme, J.C.H. Spence, T. Stehle, H.N. Chapman, C. Betzel, and M. Duszenko, In vivo protein crystallization opens new routes in structural biology. Nature Methods, 2012. 9(3): p. 259-262.

Johansson, L.C., D. Arnlund, T.A. White, G. Katona, D.P. DePonte, U. Weierstall, R.B. Doak, R.L. Shoeman, L. Lomb, E. Malmerberg, J. Davidsson, K. Nass, M. Liang, J. Andreasson, A. Aquila, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, J.D. Bozek, C. Caleman, R. Coffee, N. Coppola, T. Ekeberg, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, R. Hartmann, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, S. Kassemeyer, N. Kimmel, R.A. Kirian, F.R.N.C. Maia, S. Marchesini, A.V. Martin, C. Reich, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, J. Schulz, M.M. Seibert, R.G. Sierra, H. Soltau, D. Starodub, F. Stellato, S. Stern, L. Struder, N. Timneanu, J. Ullrich, W.Y. Wahlgren, X. Wang, G. Weidenspointner, C. Wunderer, P. Fromme, H.N. Chapman, J.C.H. Spence, and R. Neutze, Lipidic phase membrane protein serial femtosecond crystallography. Nature Methods, 2012. 9(3): p. 263-265.

Boutet, S., L. Lomb, G.J. Williams, T.R.M. Barends, A. Aquila, R.B. Doak, U. Weierstall, D.P. DePonte, J. Steinbrener, R.L. Shoeman, M. Messerschmidt, A. Barty, T.A. White, S. Kassemeyer, R.A. Kirian, M.M. Seibert, P.A. Montanez, C. Kenney, R. Herbst, P. Hart, J. Pines, G. Haller, S.M. Gruner, H.T. Philipp, M.W. Tate, M. Hromalik, L.J. Koerner, N. van Bakel, J. Morse, W. Ghonsalves, D. Arnlund, M.J. Bogan, C. Caleman, R. Fromme, C.Y. Hampton, M.S. Hunter, L.C. Johansson, G. Katona, C. Kupitz, M. Liang, A.V. Martin, K. Nass, L. Redecke, F. Stellato, N. Timneanu, D. Wang, N.A. Zatsepin, D. Schafer, J. Defever, R. Neutze, P. Fromme, J.C.H. Spence, H.N. Chapman, and I. Schlichting, High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography. Science, 2012. 337(6092): p. 362-364.

Barty, A., C. Caleman, A. Aquila, N. Timneanu, L. Lomb, T.A. White, J. Andreasson, D. Arnlund, S. Bajt, T.R.M. Barends, M. Barthelmess, M.J. Bogan, C. Bostedt, J.D. Bozek, R. Coffee, N. Coppola, J. Davidsson, D.P. DePonte, R.B. Doak, T. Ekeberg, V. Elser, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, P. Fromme, H. Graafsma, L. Gumprecht, J. Hajdu, C.Y. Hampton, R. Hartmann, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, M.S. Hunter, L. Johansson, S. Kassemeyer, N. Kimmel, R.A. Kirian, M. Liang, F.R.N.C. Maia, E. Malmerberg, S. Marchesini, A.V. Martin, K. Nass, R. Neutze, C. Reich, D. Rolles, B. Rudek, A. Rudenko, H. Scott, I. Schlichting, J. Schulz, M.M. Seibert, R.L. Shoeman, R.G. Sierra, H. Soltau, J.C.H. Spence, F. Stellato, S. Stern, L. Struder, J. Ullrich, WangX, G. Weidenspointner, U. Weierstall, C.B. Wunderer, and H.N. Chapman, Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nature Photonics, 2012. 6(1): p. 35-40.

Aquila, A., M.S. Hunter, R.B. Doak, R.A. Kirian, P. Fromme, T.A. White, J. Andreasson, D. Arnlund, S.a. Bajt, T.R.M. Barends, M. Barthelmess, M.J. Bogan, C. Bostedt, H. Bottin, J.D. Bozek, C. Caleman, N. Coppola, J. Davidsson, D.P. DePonte, V. Elser, S.W. Epp, B. Erk, H. Fleckenstein, L. Foucar, M. Frank, R. Fromme, H. Graafsma, I. Grotjohann, L. Gumprecht, J. Hajdu, C.Y. Hampton, A. Hartmann, R. Hartmann, S. Hau-Riege, G. Hauser, H. Hirsemann, P. Holl, J.M. Holton, A. Hömke, L. Johansson, N. Kimmel, S. Kassemeyer, F. Krasniqi, K.-U. Kühnel, M. Liang, L. Lomb, E. Malmerberg, S. Marchesini, A.V. Martin, F.R.N.C. Maia, M. Messerschmidt, K. Nass, C. Reich, R. Neutze, D. Rolles, B. Rudek, A. Rudenko, I. Schlichting, C. Schmidt, K.E. Schmidt, J. Schulz, M.M. Seibert, R.L. Shoeman, R. Sierra, H. Soltau, D. Starodub, F. Stellato, S. Stern, L. Strüder, N. Timneanu, J. Ullrich, X. Wang, G.J. Williams, G. Weidenspointner, U. Weierstall, C. Wunderer, A. Barty, J.C.H. Spence, and H.N. Chapman, Time-resolved protein nanocrystallography using an X-ray free-electron laser. Optics Express, 2012. 20(3): p. 2706-2716.

2011

H. N. Chapman et al., Femtosecond X-ray protein nanocrystallography. Nature470, 73-77 (2011).

Seibert, M.M., et. al. 2011. 470(7332): p. 78-81.

Lomb, L., T.R.M. Barends, S. Kassemeyer, A. Aquila, S.W. Epp, B. Erk, L. Foucar, R. Hartmann, B. Rudek, D. Rolles, A. Rudenko, R.L. Shoeman, J. Andreasson, S. Bajt, M. Barthelmess, A. Barty, M.J. Bogan, C. Bostedt, J.D. Bozek, C. Caleman, R. Coffee, N. Coppola, D.P. DePonte, R.B. Doak, T. Ekeberg, H. Fleckenstein, P. Fromme, M. Gebhardt, H. Graafsma, L. Gumprecht, C.Y. Hampton, A. Hartmann, G. Hauser, H. Hirsemann, P. Holl, J.M. Holton, M.S. Hunter, W. Kabsch, N. Kimmel, R.A. Kirian, M. Liang, F.R.N.C. Maia, A. Meinhart, S. Marchesini, A.V. Martin, K. Nass, C. Reich, J. Schulz, M.M. Seibert, R. Sierra, H. Soltau, J.C.H. Spence, J. Steinbrener, F. Stellato, S. Stern, N. Timneanu, X. Wang, G. Weidenspointner, U. Weierstall, T.A. White, C. Wunderer, H.N. Chapman, J. Ullrich, L. Strüder, and I. Schlichting, Radiation damage in protein serial femtosecond crystallography using an X-ray free-electron laser. Physical Review B, 2011. 84(21): p. 214111.

Kirian, R.A., T.A. White, J.M. Holton, H.N. Chapman, P. Fromme, A. Barty, L. Lomb, A. Aquila, F.R.N.C. Maia, A.V. Martin, R. Fromme, X. Wang, M.S. Hunter, K.E. Schmidt, and J.C.H. Spence, Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals. Acta Crystallographica Section A: Foundations of Crystallography, 2011. 67(Part 2): p. 131-140.

Hunter, M.S. and P. Fromme, Toward structure determination using membrane–protein nanocrystals and microcrystals. Methods, 2011. 55(4): p. 387-404.

Hunter, M.S., D.P. DePonte, D.A. Shapiro, R.A. Kirian, X. Wang, D. Starodub, S. Marchesini, U. Weierstall, R.B. Doak, J.C.H. Spence, and P. Fromme, X-ray Diffraction from Membrane Protein Nanocrystals. Biophysical Journal, 2011. 100(1): p. 198-206.

Fromme, P. and J.C.H. Spence, Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination. Current Opinion in Structural Biology, 2011. 21(4): p. 509-516.

Chapman, H.N., et. al. Nature, 2011. 470(7332): p. 73-77.

2010

Kirian, R.A., X. Wang, U. Weierstall, K.E. Schmidt, J.C.H. Spence, M. Hunter, P. Fromme, T. White, H.N. Chapman, and J. Holton, Femtosecond protein nanocrystallography—data analysis methods. Optics express, 2010. 18(6): p. 5713-5723.

2009

Weierstall, U., R.B. Doak, J.C.H. Spence, D. Starodub, D. Shapiro, P. Kennedy, J. Warner, G.G. Hembree, P. Fromme, and H.N. Chapman, Droplet streams for serial crystallography of proteins. Experiments in Fluids, 2008. 44(5): p. 675-689.

Starodub, D., P. Rez, G. Hembree, M. Howells, D. Shapiro, H.N. Chapman, P. Fromme, K. Schmidt, U. Weierstall, R.B. Doak, and J.C.H. Spence, Dose, exposure time and resolution in serial X-ray crystallography. Journal of synchrotron radiation, 2008. 15(1): p. 62-73.

Shapiro, D.A., H.N. Chapman, D. DePonte, R.B. Doak, P. Fromme, G. Hembree, M. Hunter, S. Marchesini, K. Schmidt, J. Spence, D. Starodub, and U. Weierstall, Powder diffraction from a continuous microjet of submicrometer protein crystals. Journal of Synchrotron Radiation, 2008. 15(6): p. 593-599.

2008

Spence, J.C.H., K. Schmidt, J.S. Wu, G. Hembree, U. Weierstall, B. Doak, and P. Fromme, Diffraction and imaging from a beam of laser-aligned proteins: resolution limits. Acta Crystallographica Section A: Foundations of Crystallography, 2005. 61(2): p. 237-245.