News & Events

Catching rays with DNA

September 24, 2016

DNA nanotechnology is a field that is one part chemistry and one part architecture, but with scientists using building materials that are 50,000 times smaller than a human hair. Now imagine using the coiled strands of DNA, wrapped end over end, to build tiny robots that could enter the body and deliver drugs exactly where they need to go, or nanoscale solar panels that work to provide more renewable energy. That is the promise, excitement and long term dream of this technology. “I was...

Thermodynamic and Kinetics of DNA Tile-based Self-assembly

November 19, 2015

Department of Physics Colloquia with Yan Liu, Ph.D., Associate Professor, Biodesign Center for Molecular Design and Biomimetics.   

Rare form: novel structures built from DNA emerge

July 20, 2015

DNA, the molecular foundation of life, has new tricks up its sleeve. The four bases from which it is composed snap together like jigsaw pieces and can be artificially manipulated to construct endlessly varied forms in two and three dimensions. The technique, known as DNA origami, promises to bring futuristic microelectronics and biomedical innovations to market. Hao Yan, a researcher at Arizona State University’s Biodesign Institute, has worked for many years to refine the technique....

ASU Biodesign Institute scientists develop innovative twists to DNA nanotechnology

March 21, 2013

In a new discovery that represents a major step in solving a critical design challenge, Arizona State University Professor Hao Yan has led a research team to produce a wide variety of 2-D and 3-D structures that push the boundaries of the burgeoning field of DNA nanotechnology. The field of DNA nanotechnology utilizes nature’s design rules and the chemical properties of DNA to self-assemble into an increasingly complex menagerie of molecules for biomedical and electronic applications. Some...

DNA art imitates life: Construction of a nanoscale Mobius strip

October 4, 2010

The enigmatic Möbius strip has long been an object of fascination, appearing in numerous works of art, most famously a woodcut by the Dutchman M.C. Escher, in which a tribe of ants traverses the form's single, never-ending surface. Scientists at the Biodesign Institute at Arizona State University and Department of Chemistry and Biochemistry, led by Hao Yan and Yan Liu, have now reproduced the shape on a remarkably tiny scale, joining up braid-like segments of DNA to create Möbius structures...

The Gold Standard: Biodesign Institute researchers use nanoparticles to make 3-D DNA nanotubes

January 1, 2009

Arizona State University researchers Hao Yan and Yan Liu imagine and assemble intricate structures on a scale almost unfathomably small. Their medium is the double-helical DNA molecule, a versatile building material offering near limitless construction potential. In the January 2, 2009 issue of Science, Yan and Liu, researchers at ASU’s Biodesign Institute and faculty in the Department of Chemistry and Biochemistry, reveal for the first time the three-dimensional character of DNA...