Publications

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2020

  1. J. Zook, M. Shekhar, D. Hansen, C. Conrad, T. Grant, C. Gupta, T. White, A. Barty, S. Basu, Y. Zhao, N. Zatsepin, A. Ishchenko, A. Batyuk, C. Gati, C. Li, L. Galli, J. Coe, M. Hunter, M. Liang, U. Weierstall, G. Nelson, D. James, B. Stauch, F. Craciunescu, D. Thifault, W. Liu, V. Cherezov, A. Singharoy, P. Fromme. (2020) XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure. Available online 5 March 2020.


2019

  1. A. Ishchenko, B. Stauch, G.W. Han, A. Batyuk, A. Shiriaeva, C. Li, N. Zatsepin, U. Weierstall, W. Liu, E. Nango, T. Nakane, R. Tanaka, K. Tono, Y. Joti, S. Iwata, I. Moraes, C. Gati, and V. Cherezov. (2019) Toward G protein-coupled receptor structure-based drug design using X-ray lasers. IUCrJ. Vol. 6, 1106-1119.

  2. A. Luginina, A. Gusach, E. Marin, A. Mishin, R. Brouillette, P. Popov, A. Shiriaeva, É. Besserer-Offroy, J. Longpré, E. Lyapina, A. Ishchenko, N. Patel, V. Polovinkin, N. Safronova, A. Bogorodskiy, E. Edelweiss, H. Hu, U. Weierstall, W. Liu, A. Batyuk, V. Gordeliy, G.W. Han, P. Sarret, V. Katritch, V. Borshchevskiy, and V. Cherezov. (2019) Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs. Sci Adv. Vol. 5, no. 10, eaax2518.

  3. J. Duan, J. Li, G.L. Chen, Y. Ge, J. Liu, K. Xie, X. Peng, W. Zhou, J. Zhong, Y. Zhang, J. Xu, C. Xue, B. Liang, L. Zhu, W. Liu, C. Zhang, X.L. Tian, J. Wang, D.E. Clapham, B. Zeng, Z. Li, J. Zhang. (2019) Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. Sci Adv. Jul 24;5(7):eaaw7935.

  4. B. Stauch, L.C. Johansson, J.D. McCorvy, N. Patel, G.W. Han, X-P. Huang, C. Gati, A. Batyuk, S.T. Slocum, A. Ishchenko, W. Brehm, T.A. White, N. Michaelian, C. Madsen, L. Zhu, T.D. Grant, J.M. Grandner, A. Shiriaeva, R.H. J. Olsen, A.R. Tribo, S. Yous, R.C. Stevens, U. Weierstall, V. Katritch, B.L. Roth*, Wei Liu*, V. Cherezov*. (2019)  Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature. 569: 284-298.

  5. L.C. Johansson, B. Stauch, J.D. McCorvy, G.W. Han, N. Patel, X-P Huang, A. Batyuk, C. Gati, S.T. Slocum, C. Li, J.M. Grandner, S. Hao, R.H.J. Olsen, A.R. Tribo, S. Zaare, L. Zhu, N.A. Zatsepin, U. Weierstall, S. Yous, R.C. Stevens, W. Liu, B.L. Roth*, V. Katritch*, V. Cherezov*. (2019) XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature. 569: 289-292.

  6. J.M. Martin-Garcia, L. Zhu, D. Mendez, M.-Y. Lee, E. Chun, C. Li, H. Hu, G. Subramanian, D. Kissick, C. Ogata, R. Henning, A. Ishchenko, Z. Dobson, S. Shang, U. Weierstall, J.C.H. Spence, P. Fromme, N.A. Zatsepin, R.F. Fischetti, V. Cherezov*, and W. Liu*. (2019) High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. IUCrJ. https://doi.org/10.1107/S205225251900263X.

  7. S. Du, L. Zhu, Y. Wang, J. Liu, D. Zhang, Y. Chen, Q. Peng, W. Liu*, and B. Liu. (2018) SENP1-mediated deSUMOylation of USP28 regulated HIF-1α accumulation and activation during hypoxia response. Cancer Cell Int. 2019 Jan 3;19:4. doi: 10.1186/s12935-018-0722-9. eCollection 2019.

  8. M. Audet, K.L. White, B. Breton, B. Zarzycka, G.W. Han, Y. Lu, C. Gati, A. Batyuk, P. Popov, J. Velasquez, D. Manahan, H. Hu, U. Weierstall, W. Liu, W. Shui, V. Katritch, V. Cherezov, M.A. Hanson, R.C. Stevens. (2019) Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor. Nat Chem Biol. 15, 11–17.


2018

  1. E.E. Abola, U. Weierstall, W. Liu and V. Cherezov. (2018) Delivery of GPCR Crystals for Serial Femtosecond Crystallography. in Protein Crystallography: Challenges and Practical Solutions Chapter 2: 28-53.

  2. L. Zhu, M.Y. Lee, E. Chun, B. Liu, and W. Liu*. (2018) Overview of Biochemical Assays in Lipidic Cubic Phase. Trends Biochem Sci 2018 Sep 19. pii: S0968-0004(18)30159-2. doi: 10.1016/j.tibs.2018.08.008. [Epub ahead of print]

  3. T. Lan, J.L. Wierman, M.W. Tate, H.T. Philipp, J.M. Martin-Garcia, L. Zhu, D. Kissick, P. Fromme, R.F. Fischetti, W. Liu, V. Elser and S.M. Gruner. (2018) Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source. IUCrJ. https://doi.org/10.1107/S205225251800903X.


2017

  1. D. Li, S. Liu, L. Zhu, Y. Wang, Y. Chen, J. Liu, G. Hu, X. Yu, J. Li, Z. Wu, H. Lu, W. Liu*, and B. Liu*. (2017) FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death. Oncotarget. https://doi.org/10.18632/oncotarget.21843

  2. A. Ishchenko, D. Wacker, M. Kapoor, A. Zhang, G.W. Han, S. Basu, N. Patel, M. Messerschmidt, U. Weierstall, W. Liu, V. Katritch, B.L. Roth, R.C. Stevens, and Vadim Cherezov. (2017) Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proc Natl Acad Sci.114: 8223-8228.

  3. J.M. Martin-Garcia, C.E. Conrad, G. Nelson, N. Stander, N.A. Zatsepin, J. Zook, L. Zhu, J. Geiger, E. Chun, D. Kissick, M.C. Hilgart, C. Ogata, A. Ishchenko, N. Nagaratnam, S. Roy-Chowdhury, J. Coe, G. Subramanian, A. Schaffer, D. James, G. Ketwala, N. Venugopalan, S. Xu, S. Corcoran, D. Ferguson, U. Weierstall, J.C. H. Spence, V. Cherezov, P. Fromme, R.F. Fischetti, W. Liu*. (2017) Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ. 4:439-454. doi.org/10.1107/S205225251700570X.

  4. H. Zhang, A. Qiao, D. Yang, L. Yang, A. Dai, C. de Graaf, S. Reedtz-Runge, V. Dharmarajan, H. Zhang, G. W. Han, T.D. Grant, R.G. Sierra, U. Weierstall, G. Nelson, W. Liu, Y. Wu, L. Ma, X. Cai, G. Lin, X. Wu, Z. Geng, Y. Dong, G. Song, P.R. Griffin, J. Lau, V. Cherezov, H. Yang, M.A. Hanson, R.C. Stevens, Q.Zhao, H. Jiang, M. Wang and B. Wu. (2017) Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 546, 259–264.

  5. H. Zhang, G.W. Han, A. Batyuk, A. Ishchenko, K.L. White, N. Patel, A. Sadybekov, B. Zamlynny, M.T. Rudd, K. Hollenstein, A. Tolstikova, T.A. White, M.S. Hunter, U. Weierstall, W. Liu, K. Bagaoglu, E.L. Moore, R.D. Katz, J.M. Shipman, M. Garcia-Calvo, S. Sharma, P. Sheth, S.M. Soisson, R.C. Stevens, V. Katritch and V. Cherezov. (2017) Structural basis for selectivity and diversity in angiotensin II receptors. Nature.  544, 327–332.


2016

  1. J. Xiang, E. Chun, C. Liu, L. Jing, Z. Al-Sahouri, L. Zhu, and W. Liu*. (2016) Successful Strategies to Determine High-Resolution Structures of GPCRs. Trends Pharmacol Sci 2016 Dec;37(12):1055-1069.

  2. A. Batyuk, L. Galli, A. Ishchenko, G.W. Han, C. Gati, P.A. Popov, M-Y Lee, B. Stauch, T.A. White, A. Barty, A. Aquila, M.S. Hunter, M. Liang, S. Boutet, M. Pu, Z-J Liu, G. Nelson, D. James, C. Li, Y. Zhao, J.C.H. Spence, W. Liu, P. Fromme, V. Katritch, U. Weierstall, R.C. Stevens and V. Cherezov. (2016) Native phasing of x-ray free-electron laser data for a G protein–coupled receptor. Science Advances Vol. 2, no. 9, e1600292.

  3. A. Ishchenko, V. Cherezov, W. Liu*. (2016) Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography. J. Vis. Exp. (115), e54463, doi:10.3791/54463.

  4. T.A. White, A. Barty, W. Liu, A. Ishchenko, H. Zhang, C. Gati, N.A. Zatsepin, S. Basu, D. Oberthür, M. Metz, K.R. Beyerlein, C.H. Yoon, O.M. Yefanov, D. James, D. Wang, M. Messerschmidt, J.E. Koglin, S. Boutet, U. Weierstall, V. Cherezov. (2016) Serial femtosecond crystallography datasets from G protein-coupled receptors. Sci. Data, 3:160057. doi: 10.1038/sdata.2016.57.

  5. L. Zhu, U. Weierstall, V. Cherezov, W. Liu*. (2016) Serial Femtosecond Crystallography of Membrane Proteins. Adv Exp Med Biol. 2016;922:151-60. doi: 10.1007/978-3-319-35072-1_11.

  6. X.E. Zhou, X. Gao, A. Barty, Y. Kang, Y. He, W. Liu, A. Ishchenko, T.A. White, O. Yefanov, G.W. Han, Q. Xu, P. W. de Waal, K.M. Suino-Powell, S. Boutet, G.J. Williams, M. Wang, D. Li, M. Caffrey, H.N. Chapman, J.C.H. Spence, P. Fromme, U. Weierstall, R.C. Stevens, V. Cherezov, K. Melcher, H.E. Xu, X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex, Sci. Data, 3:160021. DOI: 10.1038/sdata.2016.21


2015

  1. H.T. Zhang, H. Unal, C. Gati, G.W. Han, W. Liu, N.A. Zatsepin, D. James, D.J. Wang, G. Nelson, U. Weierstall, M.R. Sawaya, Q.P. Xu, M. Messerschmidt, G.J. Williams, S. Boutet, O.M. Yefanov, T.A. White, C. Wang, A. Ishchenko, K.C. Tirupula, R. Desnoyer, J. Coe, C.E. Conrad, P. Fromme, R.C. Stevens, V. Katritch, S.S. Karnik, V. Cherezov, Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography, Cell, 161(2015) 833-44.

  2. D. Li, P.J. Stansfeld, M.S. Sansom, A. Keogh, L. Vogeley, N. Howe, J.A. Lyons, D. Aragao, P. Fromme, R. Fromme, S. Basu, I. Grotjohann, C. Kupitz, K. Rendek, U. Weierstall, N.A. Zatsepin, V. Cherezov, W. Liu, S. Bandaru, N.J. English, C. Gati, A. Barty, O. Yefanov, H.N. Chapman, K. Diederichs, M. Messerschmidt, S. Boutet, G.J. Williams, M. Marvin Seibert, M. Caffrey, Ternary structure reveals mechanism of a membrane diacylglycerol kinase, Nat Commun, 6(2015) 10140.

  3. R.M. Lawrence, C.E. Conrad, N.A. Zatsepin, T.D. Grant, H.G. Liu, D. James, G. Nelson, G. Subramanian, A. Aquila, M.S. Hunter, M.N. Liang, S. Boutet, J. Coe, J.C.H. Spence, U. Weierstall, W. Liu, P. Fromme, V. Cherezov, B.G. Hogue, Serial femtosecond X-ray diffraction of enveloped virus microcrystals, Structural Dynamics, 2(2015).

  4. Jim Hicks Peter Kuhn, RODRIGUEZ Angel Ernesto DAGO, Anders Carlsson, Wei Liu, Genotypic and phenotypic analysis of circulating tumor cells to monitor tumor evolution in prostate cancer patients. US Patent App. WO 2015048740 A1

  5. Y. Kang, X.E. Zhou, X. Gao, Y. He, W. Liu, A. Ishchenko, A. Barty, T.A. White, O. Yefanov, G.W. Han, Q. Xu, P.W. de Waal, J. Ke, M.H. Tan, C. Zhang, A. Moeller, G.M. West, B.D. Pascal, N. Van Eps, L.N. Caro, S.A. Vishnivetskiy, R.J. Lee, K.M. Suino-Powell, X. Gu, K. Pal, J. Ma, X. Zhi, S. Boutet, G.J. Williams, M. Messerschmidt, C. Gati, N.A. Zatsepin, D. Wang, D. James, S. Basu, S. Roy-Chowdhury, C.E. Conrad, J. Coe, H. Liu, S. Lisova, C. Kupitz, I. Grotjohann, R. Fromme, Y. Jiang, M. Tan, H. Yang, J. Li, M. Wang, Z. Zheng, D. Li, N. Howe, Y. Zhao, J. Standfuss, K. Diederichs, Y. Dong, C.S. Potter, B. Carragher, M. Caffrey, H. Jiang, H.N. Chapman, J.C. Spence, P. Fromme, U. Weierstall, O.P. Ernst, V. Katritch, V.V. Gurevich, P.R. Griffin, W.L. Hubbell, R.C. Stevens, V. Cherezov, K. Melcher, H.E. Xu, Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser, Nature, 523(2015) 561-7.

  6. R. Fromme, A. Ishchenko, M. Metz, S.R. Chowdhury, S. Basu, S. Boutet, P. Fromme, T.A. White, A. Barty, J.C. Spence, U. Weierstall, W. Liu*, V. Cherezov, Serial femtosecond crystallography of soluble proteins in lipidic cubic phase, IUCrJ, 2(2015) 545-51.

  7. G. Fenalti, N.A. Zatsepin, C. Betti, P. Giguere, G.W. Han, A. Ishchenko, W. Liu, K. Guillemyn, H. Zhang, D. James, D. Wang, U. Weierstall, J.C.H. Spence, S. Boutet, M. Messerschmidt, G.J. Williams, C. Gati, O.M. Yefanov, T.A. White, D. Oberthuer, M. Metz, C.H. Yoon, A. Barty, H.N. Chapman, S. Basu, J. Coe, C.E. Conrad, R. Fromme, P. Fromme, D. Tourwe, P.W. Schiller, B.L. Roth, S. Ballet, V. Katritch, R.C. Stevens, V. Cherezov, Structural basis for bifunctional peptide recognition at human delta-opioid receptor, Nature Structural & Molecular Biology, 22(2015) 265-8.


2014

  1. Gater, D. L.; Saurel, O.; Iordanov, I.; Liu, W.; Cherezov, V.; Milon, A., Two Classes of Cholesterol Binding Sites for the β 2 AR Revealed by Thermostability and NMR. Biophysical journal 2014, 107 (10), 2305-2312.

  2. Yin, X.; Xu, H.; Hanson, M.; Liu, W., GPCR crystallization using lipidic cubic phase technique. Current pharmaceutical biotechnology 2014, 15 (10), 971-979.

  3. Liu, W.; Ishchenko, A.; Cherezov, V., Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nat. Protocols 2014, 9 (9), 2123-2134.

  4. Liu, W.; Wacker, D.; Wang, C.; Abola, E.; Cherezov, V., Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Philosophical Transactions of the Royal Society of London B: Biological Sciences 2014, 369 (1647).

  5. Weierstall, U.; James, D.; Wang, C.; White, T. A.; Wang, D.; Liu, W.; Spence, J. C. H.; Bruce Doak, R.; Nelson, G.; Fromme, P.; Fromme, R.; Grotjohann, I.; Kupitz, C.; Zatsepin, N. A.; Liu, H.; Basu, S.; Wacker, D.; Won Han, G.; Katritch, V.; Boutet, S.; Messerschmidt, M.; Williams, G. J.; Koglin, J. E.; Marvin Seibert, M.; Klinker, M.; Gati, C.; Shoeman, R. L.; Barty, A.; Chapman, H. N.; Kirian, R. A.; Beyerlein, K. R.; Stevens, R. C.; Li, D.; Shah, S. T. A.; Howe, N.; Caffrey, M.; Cherezov, V., Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun 2014, 5.


2013

  1. Wang, C.; Wu, H.; Katritch, V.; Han, G. W.; Huang, X.-P.; Liu, W.; Siu, F. Y.; Roth, B. L.; Cherezov, V.; Stevens, R. C., Structure of the human smoothened receptor bound to an antitumour agent. Nature 2013, 497 (7449), 338-343.

  2. Wang, C.; Jiang, Y.; Ma, J.; Wu, H.; Wacker, D.; Katritch, V.; Han, G. W.; Liu, W.; Huang, X.-P.; Vardy, E.; McCorvy, J. D.; Gao, X.; Zhou, X. E.; Melcher, K.; Zhang, C.; Bai, F.; Yang, H.; Yang, L.; Jiang, H.; Roth, B. L.; Cherezov, V.; Stevens, R. C.; Xu, H. E., Structural Basis for Molecular Recognition at Serotonin Receptors. Science 2013, 340 (6132), 610-614.

  3. Wacker, D.; Wang, C.; Katritch, V.; Han, G. W.; Huang, X.-P.; Vardy, E.; McCorvy, J. D.; Jiang, Y.; Chu, M.; Siu, F. Y.; Liu, W.; Xu, H. E.; Cherezov, V.; Roth, B. L.; Stevens, R. C., Structural Features for Functional Selectivity at Serotonin Receptors. Science 2013, 340 (6132), 615-619.

  4. Siu, F. Y.; He, M.; de Graaf, C.; Han, G. W.; Yang, D.; Zhang, Z.; Zhou, C.; Xu, Q.; Wacker, D.; Joseph, J. S.; Liu, W.; Lau, J.; Cherezov, V.; Katritch, V.; Wang, M.-W.; Stevens, R. C., Structure of the human glucagon class B G-protein-coupled receptor. Nature 2013, 499 (7459), 444-449.

  5. Liu, W.; Wacker, D.; Gati, C.; Han, G. W.; James, D.; Wang, D.; Nelson, G.; Weierstall, U.; Katritch, V.; Barty, A.; Zatsepin, N. A.; Li, D.; Messerschmidt, M.; Boutet, S.; Williams, G. J.; Koglin, J. E.; Seibert, M. M.; Wang, C.; Shah, S. T. A.; Basu, S.; Fromme, R.; Kupitz, C.; Rendek, K. N.; Grotjohann, I.; Fromme, P.; Kirian, R. A.; Beyerlein, K. R.; White, T. A.; Chapman, H. N.; Caffrey, M.; Spence, J. C. H.; Stevens, R. C.; Cherezov, V., Serial Femtosecond Crystallography of G Protein–Coupled Receptors. Science 2013, 342 (6165), 1521-1524.

  6. Lane, J. R.; Chubukov, P.; Liu, W.; Canals, M.; Cherezov, V.; Abagyan, R.; Stevens, R. C.; Katritch, V., Structure-Based Ligand Discovery Targeting Orthosteric and Allosteric Pockets of Dopamine Receptors. Molecular Pharmacology 2013, 84 (6), 794-807.

  7. Gutiérrez-de-Terán, H.; Massink, A.; Rodríguez, D.; Liu, W.; Han, Gye W.; Joseph, Jeremiah S.; Katritch, I.; Heitman, Laura H.; Xia, L.; Ijzerman, Adriaan P.; Cherezov, V.; Katritch, V.; Stevens, Raymond C., The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A2A Adenosine G Protein-Coupled Receptor. Structure 2013, 21 (12), 2175-2185.


2012

  1. Wu, H.; Wacker, D.; Mileni, M.; Katritch, V.; Han, G. W.; Vardy, E.; Liu, W.; Thompson, A. A.; Huang, X.-P.; Carroll, F. I.; Mascarella, S. W.; Westkaemper, R. B.; Mosier, P. D.; Roth, B. L.; Cherezov, V.; Stevens, R. C., Structure of the human [kgr]-opioid receptor in complex with JDTic. Nature 2012, 485 (7398), 327-332.

  2. Thompson, A. A.; Liu, W.; Chun, E.; Katritch, V.; Wu, H.; Vardy, E.; Huang, X.-P.; Trapella, C.; Guerrini, R.; Calo, G.; Roth, B. L.; Cherezov, V.; Stevens, R. C., Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 2012, 485 (7398), 395-399.

  3. Santos, J. S.; Asmar-Rovira, G. A.; Han, G. W.; Liu, W.; Syeda, R.; Cherezov, V.; Baker, K. A.; Stevens, R. C.; Montal, M., Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes. Journal of Biological Chemistry 2012, 287 (51), 43063-43070.

  4. Liu, W.; Chun, E.; Thompson, A. A.; Chubukov, P.; Xu, F.; Katritch, V.; Han, G. W.; Roth, C. B.; Heitman, L. H.; IJzerman, A. P.; Cherezov, V.; Stevens, R. C., Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions. Science 2012, 337 (6091), 232-236.

  5. Fairman, James W.; Dautin, N.; Wojtowicz, D.; Liu, W.; Noinaj, N.; Barnard, Travis J.; Udho, E.; Przytycka, Teresa M.; Cherezov, V.; Buchanan, Susan K., Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis. Structure 2012, 20 (7), 1233-1243.

  6. Chun, E.; Thompson, Aaron A.; Liu, W.; Roth, Christopher B.; Griffith, Mark T.; Katritch, V.; Kunken, J.; Xu, F.; Cherezov, V.; Hanson, Michael A.; Stevens, Raymond C., Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors. Structure 2012, 20 (6), 967-976.


2011

  1. Xu, F.; Liu, W.; Hanson, M. A.; Stevens, R. C.; Cherezov, V., Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Crystal Growth & Design 2011, 11 (4), 1193-1201.

  2. Tiefenbrunn, T.; Liu, W.; Chen, Y.; Katritch, V.; Stout, C. D.; Fee, J. A.; Cherezov, V., High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment. PLoS ONE 2011, 6 (7), e22348.

  3. Shimamura, T.; Shiroishi, M.; Weyand, S.; Tsujimoto, H.; Winter, G.; Katritch, V.; Abagyan, R.; Cherezov, V.; Liu, W.; Han, G. W.; Kobayashi, T.; Stevens, R. C.; Iwata, S., Structure of the human histamine H1 receptor complex with doxepin. Nature 2011, 475 (7354), 65-70.

  4. Liu, W.; Cherezov, V., Crystallization of Membrane Proteins in Lipidic Mesophases. 2011,  (49), e2501.

  5. Joseph, J. S.; Liu, W.; Kunken, J.; Weiss, T. M.; Tsuruta, H.; Cherezov, V., Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Methods 2011, 55 (4), 342-349.

  6. Wu, B.; Chien, E. Y. T.; Mol, C. D.; Fenalti, G.; Liu, W.; Katritch, V.; Abagyan, R.; Brooun, A.; Wells, P.; Bi, F. C.; Hamel, D. J.; Kuhn, P.; Handel, T. M.; Cherezov, V.; Stevens, R. C., Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists. Science 2010, 330 (6007), 1066-1071.

 


2010

  1. Liu, W.; Hanson, M. A.; Stevens, R. C.; Cherezov, V., LCP-Tm: An Assay to Measure and Understand Stability of Membrane Proteins in a Membrane Environment. Biophysical Journal 2010, 98 (8), 1539-1548.

  2. Chien, E. Y. T.; Liu, W.; Zhao, Q.; Katritch, V.; Won Han, G.; Hanson, M. A.; Shi, L.; Newman, A. H.; Javitch, J. A.; Cherezov, V.; Stevens, R. C., Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist. Science 2010, 330 (6007), 1091-1095.

  3. Cherezov, V.; Liu, W.; Derrick, J. P.; Luan, B.; Aksimentiev, A.; Katritch, V.; Caffrey, M., In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Proteins: Structure, Function, and Bioinformatics 2008, 71 (1), 24-34.

  4. Liu, W.; Caffrey, M., Interactions of Tryptophan, Tryptophan Peptides, and Tryptophan Alkyl Esters at Curved Membrane Interfaces†. Biochemistry 2006, 45 (39), 11713-11726.

  5. Cherezov, V.; Yamashita, E.; Liu, W.; Zhalnina, M.; Cramer, W. A.; Caffrey, M., In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 Å Resolution. Journal of Molecular Biology 2006, 364 (4), 716-734.

  6. Liu, W.; Caffrey, M., Gramicidin structure and disposition in highly curved membranes. Journal of Structural Biology 2005, 150 (1), 23-40.