Publications

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2015

  1. Larrimore KE, Kannan L, Barcus M, Kendle RP, and Mor TS.. Complex kinetic behavior and increased bioscavenging potential of cocaine hydrolase mutants of plant-derived butyrylcholinesterase.. Chemico-Biological Interactions (2015) Refereed Articles.


2014

  1. Gong Z, Kessans SA, Song L, Dorner K, Lee HH, Meador LR, LaBaer J, Hogue BG, *Mor TS, *Fromme P. Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41.. Protein Sci (2014) Refereed Articles.

  2. Lee HH, Cherni I, Yu H, Fromme R, Doran JD, Grotjohann I, Mittman M, Basu S, Deb A, Dorner K, Aquila A, Barty A, Boutet S, Chapman HN, Doak RB, Hunter MS, James D, Kirian RA, Kupitz C, Lawrence RM, Liu H, Nass K, Schlichting I, Schmidt KE, Seibert MM, Sho. Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. IUCrJ. IUCrJ (2014) Refereed Articles.

  3. Meador LR, Mor TS. Meeting Report VLPNPV: Session 5: Plant based technology. Hum Vaccin Immunother (2014) Refereed Articles.

  4. Mestecky J, Russell MW, Kelsall BL, Ogra PL, Strober W, Lambrecht BN and Cheroutre H, Editors, ?Mason HS, Thuenemann E, Kiyono H, *Kessans SA and Mor TS.. Mucosal Vaccines. Mucosal vaccines from plant biotechnology. (2014) Book Chapters.

  5. Sarah A Kessans, Mark Linhart, Lydia R Meador, Jacquelyn Kilbourne, Petra Fromme, Nobuyuki Matobaa, Tsafrir S Mor. Immunological characterization of plant-based HIV-1 gag/dgp41 virus-like particles. Vaccine (2014) Refereed Articles.

  6. Schneider JD, Castilho A, Neumann L, Altmann F, Loos A, Kannan L, Mor TS, Steinkellner H. Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue.. Biotechnol J (2014) Refereed Articles.

  7. Schneider JD, Marillonnet S, Castilho A, Gruber C, Werner S, Mach L, Klimyuk V, Mor TS, Steinkellner H. Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana.. Plant Biotechnol J (2014) Refereed Articles.


2013

  1. *Geyer BC, *Larrimore KE, *Kilbourne J, *Kannan L, §Mor TS. Reversal of Succinylcholine Induced Apnea with an Organophosphate Scavenging Recombinant Butyrylcholinesterase.. PLOS One (2013).

  2. *Kessans SA, *Linhart, MD, §*Matoba N, and §Mor TS. Biological and biochemical characterization of HIV-1 Gag/dgp41 virus-like particles expressed in Nicotiana benthamiana.. Plant Biotechnol J. (2013).

  3. *Larrimore KE, *Barcus MJ, *Kannan L, Gao Y, Zhan C-G, Brimijoin S, §Mor TS. Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity.. Chem-Biol Interact. (2013).


2012

  1. *Geyer BC, Ben-Ari S, §Mor TS and §Soreq H.. Nicotinic stimulation induces Tristetraprolin over-production and attenuates inflammation in muscle.. Biochim Biophys Acta-Mol Cell Res (2012).


2011

  1. *Matoba N, *Shah NR, and §Mor TS.. Humoral immunogenicity of an HIV-1 envelope residue 649-684 membrane-proximal region peptide fused to the plague antigen F1-V. Vaccine (2011).


2010

  1. *Geyer BC, *Kannan L, *Garnaud PE, Broomfield CA, Cadieux CL, *Cherni I, Hodgins SM, Kasten SA, Kelley K, *Kilbourne J, Oliver ZP, Otto TC, *Puffenberger I, Reeves TE, *Robbins N, 2nd, *Woods RR, Soreq H, Lenz DE, Cerasoli DM, §Mor TS. Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents.. Proc Natl Acad Sci U S A (2010).

  2. *Geyer, BC, *Kannan, L, *Cherni, I, *Woods, RR, *Soreq, H, and §Mor TS. Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase.. Plant Biotechnol J (2010).


2009

  1. *Matoba N, Kajiura H, *Cherni I, *Doran JD, Alfsen A, Bomsel M, Fujiyama K and §Mor TS. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB MPR649 684.. Plant Biotechnol J (2009).

  2. Book chapter: *Geyer GC, Evron T, §Mor TS and §Soreq H. Organophosphate Intoxication: Molecular Consequences, Mechanisms and Solutions.. Toxicology of Chemical Warfare Agents. Elsevie Inc, San Diego (2009).


2008

  1. *1Geyer BC, *1Woods RR, §Mor TS. Increased organophosphate scavenging in a butyrylcholinesterase mutant.. Chemico-Biological Interactions (2008).

  2. *1Woods RR, *1Geyer BC, §Mor TS. Production of recombinant human acetylcholinesterase in hairy root cultures.. BMC Biotechnology (2008).

  3. *Matoba N, *Griffin TA, *Mittman M, *Doran JD, Alfsen A, Montefiori DC, Hanson CV, Bomsel M, and §Mor TS. Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes. Curr HIV Res 6:218-229. Current HIV Research (2008).

  4. Berson A, Knobloch M, Hanan M, Diamant S, Sharoni M, Schuppli D, *Geyer BC, Ravid R, Mor TS, Nitsch RM and §Soreq H. Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.. Brain (2008).

  5. Mor I, Sklan EH, Podoly E, Pick M, Kirschner M, Yogev L, Bar-Sheshet Itach S, Schreiber L, *Geyer B, *Mor T, Grisaru D, and §Soreq H. Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility.. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008).


2007

  1. *1Geyer BC and *1Fletcher SP, *Griffin TA, *Lopker MJ, Soreq H and §Mor, TS. Translational control of recombinant human acetylcholinesterase accumulation in plants.. BMC Biotechnol (2007).

  2. 1Evron T and *1Geyer BC, *Cherni I, *Muralidharan M, *Kilbourne J, *Fletcher SP, Soreq H and §Mor TS. Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath.. FASEB J (2007).


2006

  1. *Matoba N, *Geyer BC, *Kilbourne J, Alfsen A, Bomsel M and §Mor TS (2006) Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR649-684, a mucosal subunit HIV/AIDS vaccine candidate. Vaccine 24:5047-5055. Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR649-684, a mucosal subunit HIV/AIDS vaccine candidate. Vaccine (2006).

  2. Nobuyuki Matoba, B Geyer, J Kilbourne, A Alfsen, M Bomsel, Tsafrir Mor. Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR649-684, a mucosal subunit HIV/AIDS vaccine candidate. Vaccine (2006).

  3. S Saldaña, L Richter, C Arntzen, M Gómez Lim, F Guadarrama, T de Jesús Olivera Flores, N Arias, S López, C Arias, R Ruiz, H Mason, Tsafrir Mor. Production of rotavirus-like-particles in tomato (Lycopersicon esculentum L.) fruit by expression of capsid proteins VP2 and VP6 and immunological studies. Viral Immunol (2006).

  4. S Saldaña, L Richter, C Arntzen, M Gómez Lim, F Guadarrama, T de Jesús Olivera Flores, N Arias, S López, C Arias, R Ruiz, H Mason, Tsafrir Mor. Production of rotavirus-like-particles in tomato (Lycopersicon esculentum L.) fruit by expression of capsid proteins VP2 and VP6 and immunological studies. Viral Immunol (2006).

  5. Saldaña S, Guadarrama FE, de Jesús Olivera Flores T, Arias N, López S, Arias C, Ruiz R, Mason H, *Mor T, Richter L, Arntzen CJ and §Gómez Lim MA.. Production of rotavirus-like-particles in tomato (Lycopersicon esculentum L.) fruit by expression of capsid proteins VP2 and VP6 and immunological studies.. Viral Immunol (2006).

  6. Book chapter: MATOBA, NOBUYUKI,Mor, Tsafrir S. PLANT-DERIVED SUBUNIT VACCINES. Plant Genetic Engineering Vol. 8: Metabolic Engineering & Molecular Farming II. Studium Press, LLC, Houston, USA (2006).

  7. Fletcher, S, Soreq, H, Mor, Tsafrir, Geyer, B, Evron, E, Cherni, I, Muralidharan, M, Kilbourne, J. Plant-Derived Human Acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath: The U.S. Army Medical Research Institute of Chemical Defense (2006).


2005

  1. *Geyer BC, *Muralidharan M, *Cherni I, *Doran J, *Fletcher SP, Evron, T, Soreq H and §Mor TS (. Purification of Transgenic Plant-Derived Recombinant Human Acetylcholinesterase-R. Chemico-Biological Interactions (2005).

  2. *Muralidharan M, Soreq H and §Mor, TS. Characterizing pea acetylcholinesterase. Chemico-Biological Interactions (2005).

  3. Geyer, B, Evron, T, Cherni, I, Muralidharan, M, Patel, A, Fletcher, S, Soreq, H, Mor, Tsafrir. N. benthamiana Produced Human Acetylcholinesterase Completely Protects Mice from Lethal Doses of Organophosphate Toxins (2005).

  4. Matoba, M, Magerus, A, Geyer, B, Zhang, Y, Alfsen, A, Arntzen, C, Bomsel, M, Mor, Tsafrir. Humoral immunity induced by CTB-P1 for the Prevention of HIV-1 Mucosal Transmission/infection (2005).

  5. Matoba, M, Magerus, A, Geyer, B, Zhang, Y, Alfsen, A, Arntzen, C, Bomsel, M, Mor, Tsafrir. Towards an oral plant-derived HIV-1 subunit vaccine (2005).

  6. Matoba, N, Magérus, A, Geyer, B, Alfsen, A, Hanson, C, Arntzen, C, Bomsel, M, Mor, Tsafrir. Humoral immunity induced by CTB-MPR649-684 towards the prevention of HIV-1 mucosal transmission/infection (2005).


2004

  1. Mor, Tsafrir S, Soreq, H. Encyclopedia of Plant & Crop Science, R.M. Goodman, ed. Human cholinesterases from Plants for detoxification. Marcel Dekker, Inc., New York (2004).

  2. *Fletcher SP, *Geyer BC, Smith A, Evron T, Joshi L, Soreq H and §Mor TS. Tissue Distribution of Cholinesterases and Anticholinesterases in Native and Transgenic Tomato Plants. Plant Mol. Biol (2004).

  3. *Matoba N, Magérus A, *Geyer BC, Zhang Y, *Muralidharan M, Alfsen A, Arntzen CJ, Bomsel M and §Mor TS. Mucosally-Targeted Subunit Vaccine Candidate Eliciting HIV-1 Transcytosis-blocking Antibodies. Proc. Natl. Acad. Sci. USA (2004).

  4. Mor, Tsafrir S, Mason, H S, Kirk, D, Arntzen, C J, Cardineau, G A. Plants as a delivery vehicle for orally delivered subunit vaccines. In: New Generation Vaccines. Marcel Dekker (2004).

  5. Book chapter: Mor, Tsafrir S (Author) ,Mason, H S (Author) . Transgenic plants as a source for subunit vaccines. Handbook of Plant Biotechnology. John Wiley & Sons, Ltd., West Sussex (2004).

  6. Book chapter: Mor, Tsafrir S (Author) ,Mason, H S (Author) ,Kirk, D D (Author) ,Arntzen, C J (Author) ,Cardineau, G A (Author) . Plants as a production and delivery vehicle for orally delivered subunit vaccines. Current Vaccines. Marcel Dekker (2004).

  7. Fletcher, S, Geyer, B, Muralidharan, M, Arntzen, C, Soreq, H, Mor, Tsafrir. Chemical warfare countermeasures: Expression of human acetylcholinesterase in plants (2004).

  8. Matoba, M, Magerus, A, Geyer, B, Zhang, Y, Alfsen, A, Arntzen, C, Bomsel, M, Mor, Tsafrir. A subunit vaccine candidate to prevent HIV-1 transmission. HIV Vaccine Development (2004).

  9. Muralidharan, M, Fletcher, S, Geyer, B, Soreq, H, Mor, Tsafrir. Characterizing pea acetylcholinesterase (2004).


2003

  1. *Mor TS, Moon Y-S, Palmer, KE and §Mason, HS. Geminivirus Vectors for High Level Expression of Foreign Proteins in Plant Cells. Biotechnol. Bioeng (2003).

  2. Mor, Tsafrir S, Mason, H S. Plants as a source for subunit vaccines. In: Handbook of Plant Physiology. John Wiley and Sons (2003).