Publications

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2019

  1. Ji X, Khdour OM, Hecht SM. Multifunctional radical quenchers as potential therapeutic agents for the treatment of mitochondrial dysfunction. Future Med Chem. 2019 Jul;11(13):1605-1624. doi: 10.4155/fmc-2018-0481. PubMed PMID: 31469329.

  2. Dedkova LM, Hecht SM. Expanding the Scope of Protein Synthesis Using Modified Ribosomes. J Am Chem Soc. 2019 Apr 24;141(16):6430-6447. doi: 10.1021/jacs.9b02109. Epub 2019 Apr 5. PubMed PMID: 30901982; PubMed Central PMCID: PMC6530915. 

  3. Chen S, Ji X, Gao M, Dedkova LM, Hecht SM. In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid. J Am Chem Soc. 2019 Apr 10;141(14):5597-5601. doi: 10.1021/jacs.8b12767. Epub 2019 Mar 26. PubMed PMID: 30889951; PubMed Central PMCID: PMC6733411.


2018

  1. Bandyopadhyay I, Chowdhury SR, Visavadiya NP, Hecht SM, Khdour OM. Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels. Data Brief. 2018 Oct;20:1105-1114. doi: 10.1016/j.dib.2018.08.156. eCollection 2018 Oct. PubMed PMID: 30225325; PubMed Central PMCID: PMC6139889.

  2. Khdour OM, Bandyopadhyay I, Visavadiya NP, Roy Chowdhury S, Hecht SM. Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells. Medchemcomm. 2018 Sep 1;9(9):1491-1501. doi: 10.1039/c8md00274f. eCollection 2018 Sep 1. PubMed PMID: 30288223; PubMed Central PMCID: PMC6148561.

  3. Khdour OM, Bandyopadhyay I, Chowdhury SR, Visavadiya NP, Hecht SM. Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia. Bioorg Med Chem. 2018 Jul 23;26(12):3359-3369. doi: 10.1016/j.bmc.2018.05.005. Epub 2018 May 4. PubMed PMID: 29773347.

  4. Mastroeni D, Nolz J, Khdour OM, Sekar S, Delvaux E, Cuyugan L, Liang WS, Hecht SM, Coleman PD. Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs. Alzheimers Dement. 2018 Jun;14(6):775-786. doi: 10.1016/j.jalz.2017.12.005. Epub 2018 Jan 23. PubMed PMID: 29396107.

  5. Daskalova SM, Bai X, Hecht SM. Study of the Lyase Activity of Human DNA Polymerase β Using Analogues of the Intermediate Schiff Base Complex. Biochemistry. 2018 May 8;57(18):2711-2722. doi: 10.1021/acs.biochem.8b00308. Epub 2018 Apr 17. PubMed PMID: 29625008.


2017

  1. Rapid detection of a dengue virus RNA sequence with single molecule sensitivity using tandem toehold-mediated displacement reactions. Gao M, Daniel D, Zou H, Jiang S, Lin S, Huang C, Hecht SM, Chen S. Chem Commun (Camb). 2018 Jan 23;54(8):968-971. doi: 10.1039/c7cc09131a. PMID: 29319084

  2. Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction. Roy Chowdhury S, Khdour OM, Bandyopadhyay I, Hecht SMBioorg Med Chem. 2017 Oct 15;25(20):5537-5547. doi: 10.1016/j.bmc.2017.08.021. Epub 2017 Aug 18. PMID: 28927904

  3. Incorporation of Phosphorylated Tyrosine into Proteins: In Vitro Translation and Study of Phosphorylated IκB-α and Its Interaction with NF-κB. Chen S, Maini R, Bai X, Nangreave RC, Dedkova LM, Hecht SMJ Am Chem Soc. 2017 Oct 11;139(40):14098-14108. doi: 10.1021/jacs.7b05168. Epub 2017 Sep 27. PMID: 28898075

  4. Inhibition of Human Cancer Cell Growth by Analogues of Antimycin A. Zhang Y, Chevalier A, Khdour OM, Soto LM, Hecht SMPlanta Med. 2017 Dec;83(18):1377-1383. doi: 10.1055/s-0043-112343. Epub 2017 Jun 8. PMID: 28597454

  5. Arutla V, Leal J, Liu X, Sokalingam S, Raleigh M, Adaralegbe A, Liu L, Pentel PR, Hecht SM, Chang Y. Prescreening of Nicotine Hapten Linkers in Vitro To Select Hapten-Conjugate Vaccine Candidates for Pharmacokinetic Evaluation in Vivo. ACS Comb Sci. 2017 May 8;19(5):286-298. doi: 10.1021/acscombsci.6b00179. Epub 2017 Apr 17. PubMed PMID: 28383252.

  6. Bai X, Talukder P, Daskalova SM, Roy B, Chen S, Li Z, Dedkova LM, Hecht SM. Enhanced Binding Affinity for an i-Motif DNA Substrate Exhibited by a Protein Containing Nucleobase Amino Acids. J Am Chem Soc. 2017 Apr 5;139(13):4611-4614. doi: 10.1021/jacs.6b11825. Epub 2017 Mar 17. PubMed PMID: 28263595.

  7. Chevalier A, Khdour OM, Schmierer M, Bandyopadhyay I, Hecht SM. Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants. Bioorg Med Chem. 2017 Mar 1;25(5):1703-1716. doi: 10.1016/j.bmc.2017.01.030. Epub 2017 Jan 23. PubMed PMID: 28189395.

  8. Daskalova SM, Bhattacharya C, Dedkova LM, Hecht SM. Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues. Biochemistry. 2017 Jan 24;56(3):500-513. doi: 10.1021/acs.biochem.6b00807. Epub 2017 Jan 12. PubMed PMID: 28005340.

  9. Zhang Y, Jiang S, Zhang D, Bai X, Hecht SM, Chen S. DNA-affibody nanoparticles for inhibiting breast cancer cells overexpressing HER2. Chem Commun (Camb). 2017  Jan 3;53(3):573-576. doi: 10.1039/c6cc08495h. PubMed PMID: 27975087.


2016

  1. Mastroeni D, Khdour OM, Delvaux E, Nolz J, Olsen G, Berchtold N, Cotman C, Hecht SM, Coleman PD. Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease. Alzheimers Dement. 2017 May;13(5):510-519. doi: 10.1016/j.jalz.2016.09.003. Epub 2016 Oct 25. PubMed PMID: 27793643.

  2. Chevalier A, Alam MP, Khdour OM, Schmierer M, Arce PM, Cripe CD, Hecht SM. Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP  production and metabolic stability. Bioorg Med Chem. 2016 Nov 1;24(21):5206-5220. doi: 10.1016/j.bmc.2016.08.039. Epub 2016 Aug 23. PubMed PMID: 27624526.

  3. Kendrick S, Kang HJ, Alam MP, Madathil MM, Agrawal P, Gokhale V, Yang D, Hecht SM, Hurley LH. Correction to "The Dynamic Character of the BCL2 Promoter i-Motif  Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure". J Am Chem Soc. 2016 Sep 7;138(35):11408. doi: 10.1021/jacs.6b07292. Epub 2016 Aug 29. PubMed PMID: 27571358.

  4. Chevalier A, Zhang Y, Khdour OM, Kaye JB, Hecht SM. Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting. J Am Chem Soc. 2016 Sep 21;138(37):12009-12. doi: 10.1021/jacs.6b06229. Epub 2016 Sep 7. PubMed PMID: 27571326.

  5. Roy B, Talukder P, Kang HJ, Tsuen SS, Alam MP, Hurley LH, Hecht SM. Interaction of Individual Structural Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA. J Am Chem Soc. 2016 Aug 31;138(34):10950-62. doi: 10.1021/jacs.6b05036. Epub 2016 Aug 17. PubMed PMID: 27483029.

  6. Talukder P, Dedkova LM, Ellington AD, Yakovchuk P, Lim J, Anslyn EV, Hecht SM. Synthesis of alanyl nucleobase amino acids and their incorporation into proteins. Bioorg Med Chem. 2016 Sep 15;24(18):4177-87. doi: 10.1016/j.bmc.2016.07.008. Epub 2016 Jul 6. PubMed PMID: 27452282; PubMed Central PMCID: PMC4992614.

  7. Chevalier A, Zhang Y, Khdour OM, Hecht SM. Selective Functionalization of Antimycin A Through an N-Transacylation Reaction. Org Lett. 2016 May 20;18(10):2395-8. doi: 10.1021/acs.orglett.6b00882. Epub 2016 May 11. PubMed PMID: 27168333.

  8. Chowdhury SR, Chauhan PS, Dedkova LM, Bai X, Chen S, Talukder P, Hecht SM. Synthesis and Evaluation of a Library of Fluorescent Dipeptidomimetic Analogues as Substrates for Modified Bacterial Ribosomes. Biochemistry. 2016 May 3;55(17):2427-40. doi: 10.1021/acs.biochem.6b00102. Epub 2016 Apr 21. PubMed PMID: 27050631.


2015

  1. Talukder P, Chen S, Roy B, Yakovchuk P, Spiering MM, Alam MP, Madathil MM, Bhattacharya C, Benkovic SJ, Hecht SM. Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction. Biochemistry. 2015 Dec 29;54(51):7457-69. doi: 10.1021/acs.biochem.5b01085. Epub 2015 Dec 16. PubMed PMID: 26618501.

  2. Chowdhury SR, Maini R, Dedkova LM, Hecht SM. Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4715-8. doi: 10.1016/j.bmcl.2015.08.073. Epub 2015 Aug 29. PubMed PMID: 26351043; PubMed Central PMCID: PMC4607672.

  3. Maini R, Dedkova LM, Paul R, Madathil MM, Chowdhury SR, Chen S, Hecht SM. Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro. J Am Chem Soc. 2015 Sep 9;137(35):11206-9. doi: 10.1021/jacs.5b03135. Epub 2015 Aug 31. PubMed PMID: 26301427.

  4. Gerasimova YV, Yakovchuk P, Dedkova LM, Hecht SM, Kolpashchikov DM. Expedited quantification of mutant ribosomal RNA by binary deoxyribozyme (BiDz) sensors. RNA. 2015 Oct;21(10):1834-43. doi: 10.1261/rna.052613.115. Epub 2015 Aug 19. PubMed PMID: 26289345; PubMed Central PMCID: PMC4574759.

  5. J. A. Bernatchez, R. Paul, E. P. Tchesnokov, M. Ngure, G. L. Beilhartz, A. M. Berghuis, R. Lavoie, L. Li, A. Auger, R. A. Melnyk, J. A. Grobler, M. D. Miller, D. J. Hazuda, S. M. Hecht and M. Götte, Derivatives of Mesoxalic Acid Block Translocation of HIV-1 Reverse Transcriptase, J. Biol. Chem., 290, 1474-1484 (2015).

  6. Z. Wang, P. Talukder, S. M. Hecht and S. Chen, Fluorescent CD4 Probe for Potential HIV-1 gp120 Protein Detection, Bioorg. Med. Chem. Lett. 25, 1182-1185 (2015).

  7. D. Mastroeni, O. M. Khdour, P. M. Arce, S. M. Hecht and P. D. Coleman, Novel Antioxidants Protect Mitochondria from the Effects of Oligomeric Amyloid Beta and Contribute to the Maintenance of Epigenome Function, ACS Chem. Neurosci,, 6, 588-598 (2015).

  8. Z. Yu, R. Paul, C. Bhattacharya, T. C. Bozeman, M. J. Rishel, and S. M. Hecht, Structural Features Facilitating Tumor Cell Targeting and Internalization by Bleomycin and its Disaccharide, Biochemistry, 54, 3100-3109 (2015).

  9. R. Maini, S. R. Chowdhury, L. M. Dedkova, B. Roy, S. M. Daskalova, R. Paul, S. Chen and S. M. Hecht, Protein Synthesis with Ribosomes Selected for the Incorporation of  b-Amino Acids, Biochemistry, 54, 3694-3706 (2015).

  10. Y. V. Gerasimova, P. Yakovchuk, L. M. Dedkova, S. M. Hecht and D. M. Kolpashchikov, Expedited Quantification of Mutant ribosomal RNA by Binary Deoxyribosome (BiDz) Sensors, RNA, 21, 1834-1843 (2015).

  11. R. Maini, L. M. Dedkova, R. Paul, M. M. Madathil, S. R. Chowdhury, S. Chen, and S. M. Hecht, Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro, J. Am. Chem. Soc., 137, 11206-11209 (2015).

  12. S. R. Chowdhury, R. Maini, L. M. Dedkova and S. M. Hecht, Synthesis of Fluorescent Dipeptidomimetics and their Ribosomal Incorporation into Green Fluorescent Protein, Bioorg. Med. Chem. Lett., 25, 4715-4718 (2015).

  13. P. Talukder, S. Chen, B. Roy, P. Yakovchuk, M. M. Spiering, M. P. Alam, M. M. Madathil, C. Bhattacharya, S. J. Benkovic and S. M. Hecht, Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA–Protein Interaction, Biochemistry, 54, 7457-7469 (2015).


2014

  1. B. R. Schroeder, M. I. Ghare, C. Bhattacharya, R. Paul, Z. Yu, P. A. Zaleski, T. C. Bozeman, M. J. Rishel and S. M. Hecht. The Disaccharide Moiety of Bleomycin Facilitates Uptake by Cancer Cells. Journal of the American Chemical Society (2014).

  2. B. Roy and S. M. Hecht. Hairpin DNA Sequences Bound Strongly by Bleomycin Exhibit Enhanced Double-Strand Cleavage. Journal of the American Chemical Society (2014).

  3. B. Roy, C. Tang, M. P. Alam and S. M. Hecht. DNA Methylation Reduces Binding and Cleavage by Bleomycin. Biochemistry (2014).

  4. C. Bhattacharya, Z. Yu, M. J. Rishel and S. M. Hecht. The Carbamoylmannose Moiety of Bleomycin Mediates Selective Tumor Cell Targeting. Biochemistry (2014).

  5. C. Tang, A. Paul, M. P. Alam, B. Roy, W. D. Wilson and S. M. Hecht. A Short DNA Sequence Confers Strong Bleomycin Binding to Hairpin DNAs. Journal of the American Chemical Society (2014).

  6. H.-J. Kang, S. Kendrick, S. M. Hecht and L. H. Hurley. The Transcriptional Complex Between the BCL2 i-Motif and hnRNP LL is a Molecular Switch for Control of Gene Expression that can be Modulated by Small Molecules. Journal of the American Chemical Society (2014).

  7. M. M. Madathil, C. Bhattacharya, Z. Yu, R. Paul, M. J. Rishel and S. M. Hecht. Modified Bleomycin Disaccharides Exhibiting Improved Tumor Cell Targeting. Biochemistry (2014).

  8. M. P. Alam, O. M. Khdour, P. M. Arce, B. Roy, W. G. Johnson, Y. Chen, S. Dey and S. M. Hecht. Cytoprotective Pyridinol Antioxidants as Potential Therapeutic Agents for Neurodegenerative and Mitochondrial Diseases. Bioorganic Medicinal Chemistry (2014).

  9. P. Talukder, S. Chen, C. T. Liu, E. A. Baldwin, S. J. Benkovic and S. M. Hecht. Tryptophan-based Fluorophores for Studying Protein Conformational Changes. Bioorganic Medicinal Chemistry (2014).

  10. P. Talukder, S. Chen, P. M. Arce and S. M. Hecht. Efficient Asymmetric Synthesis of Tryptophan Analogues Having Useful Photophysical Properties. Organic Letters (2014).

  11. S. Kendrick, H.-J. Kang, M. P. Alam, M. M. Madathil, P. Agrawal, V. Gokhale, D. Yang, S. M. Hecht and L. H. Hurley. The Dynamic Character of the BCL-2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds that Bind Selectively to the Alternative DNA Species. Journal of the American Chemical Society (2014).

  12. X. Yu, P. Talukder, C. Bhattacharya, N. E. Fahmi, J. A. Lines, L. M. Dedkova, J. LaBaer, S. M. Hecht and S. Chen. Probing the CD4 Binding Pocket of HIV-1 gp120 Glycoprotein Using Unnatural Phenylalanine Analogues. Bioorganic Medicinal Chemistry Letters (2014).


2013

  1. D. M. Fash, O. M. Khdour, S. J. Sahdeo, R. Goldschmidt, J. Jaruvangsanti, S. Dey, P. M. Arce, V. C. Collin, G. A. Cortopassi and S. M. Hecht. Effects of Alkyl Side Chain Modification of Coenzyme Q10 on Mitochondrial Respiratory Chain Function and Cytoprotection. Bioorganic Medicinal Chemistry (2013).

  2. M. M. Madathil, O. M. Khdour, J. Jaruvangsanti and S. M. Hecht. A Structurally Simplified Analogue of Geldanamycin Exhibits Neuroprotective Activity. ACS Medicinal Chemistry Letters (2013).

  3. O. M. Khdour, P. M. Arce, B. Roy and S. M. Hecht. An Optimized Pyrimidinol Multifunctional Radical Quencher. ACS Medicinal Chemistry Letters (2013).

  4. R. Goldschmidt, P. M. Arce, O. M. Khdour, V. C. Collin, S. Dey, J. Jaruvangsanti, D. M. Fash and S. M. Hecht. Effects of Cytoprotective Antioxidants on Lymphocytes from Representative Mitochondrial Neurodegenerative Diseases. Bioorganic Medicinal Chemistry (2013).

  5. R. M. Mrozowski, R. Vemula, B. Wu, Q. Zhang, B. R. Schroeder, M. K. Hilinski, D. E. Clark, S. M. Hecht, G. A. O’Doherty, and D. A. Lannigan. Improving the Affinity of SL0101 for RSK Using Structure-Based Design. ACS Medicinal Chemistry Letters (2013).

  6. R. Maini, D. Nguyen, S. Chen, L. M. Dedkova, S. Roy Chowdhury, R. Alcala-Torano and S. M. Hecht. Incorporation of beta-Amino Acids into Dihydrofolate Reductase by Ribosomes Having Modifications in the Peptidyltransferase Center. Bioorganic Medicinal Chemistry (2013).

  7. S. Chen, N. E. Fahmi, C. Bhattacharya, L. Wang, Y. Jin, S. J. Benkovic and S. M. Hecht. Fluorescent Biphenyl Derivatives of Phenylalanine Suitable for Protein Modification. Biochemistry (2013).

  8. S. Chen, N. E. Fahmi, L. Wang, C. Bhattacharya, S. J. Benkovic and S. M. Hecht. Detection of DHFR Conformational Change by FRET Using Two Fluorescent Amino Acids. Journal of the American Chemical Society (2013).

  9. Z. J. Segerman, B. Roy and S. M. Hecht. Characterization of Bleomycin-Mediated Cleavage of a Hairpin DNA Library. Biochemistry (2013).

  10. Z. Yu, R. M. Schmaltz, T. C. Bozeman, R. Paul, M. J. Rishel, K. S. Tsosie and S. M. Hecht. Selective Tumor Cell Targeting by the Disaccharide Moiety of Bleomycin. Journal of the American Chemical Society (2013).


2012

  1. L. M. Dedkova, N. E. Fahmi, R. Paul, M. del Rosario, L. Zhang, S. Chen, G. Feder and S. M. Hecht. ß-Puromycin Selection of Modified Ribosomes for in vitro Incorporation of ß-Amino Acids. Biochemistry (2012).

  2. M. M. Madathil, O. M. Khdour, J. Jaruvangsanti and S. M. Hecht. Synthesis and Biological Activities of N-(3-carboxypropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and Analogues. Journal of Natural Products (2012).

  3. P. A. Zaleski, R. Maini, S. J. Leiris, M. A. Elban and S. M. Hecht. Synthesis and Biological Activities of Topopyrones. Journal of Natural Products (2012).

  4. P. M. Arce, R. Goldschmidt, O. M. Khdour, M. M. Madathil, J. Jaruvangsanti, S. Dey, D. M. Fash, J. S. Armstrong and S. M. Hecht. Analysis of the Structural and Mechanistic Factors in Antioxidants that Preserve Mitochondrial Function and Confer Cytoprotection. Bioorganic Medicinal Chemistry (2012).

  5. S. Chen, L. Wang, N. E. Fahmi, S. J. Benkovic and S. M. Hecht. Two Pyrenylalanines in Dihydrofolate Reductase Form an Excimer Enabling the Study of Protein Dynamics. Journal of the American Chemical Society (2012).

  6. S. Chen, N. E. Fahmi, R. C. Nangreave, Y. Mehellou and S. M. Hecht. Synthesis of pdCpAs and Transfer RNAs Activated with Thiothreonine and Derivatives. Bioorganic Medicinal Chemistry (2012).

  7. T. C. Bozeman, R. K. Nanjunda, C. Tang, Y. Liu, Z. J. Segerman, P. A. Zaleski, W. D. Wilson and S. M. Hecht. Dynamics of Bleomycin Interaction with a Strongly Bound Hairpin DNA Substrate, and Implications for Cleavage of the Bound DNA. Journal of the American Chemical Society (2012).

  8. X. Cai, O. M. Khdour, J. Jaruvangsanti and S. M. Hecht. Simplified Bicyclic Pyridinol Analogues Protect Mitochondrial Function. Bioorganic Medicinal Chemistry (2012).


2011

  1. H. Rosso, V. Richard, M. DePaolis, V. C. Collin, S. Dey, S.M. Hecht, C. Prandi and J. Maddaluno. One-Pot Regio- and Stereoselective Diversity-Oriented Synthesis of a’- Methoxy-?-Pyrones from a’, a’-Dimethoxy-?-Pyrone. Journal of Organic Chemistry (2011).

  2. M. Duca, C. Trindle and S.M. Hecht. Structural Basis for the Exceptional Stability of Bisaminoacylated Nucleotides and Transfer RNAs. Journal of the American Chemical Society (2011).

  3. O.M. Khdour, J. Lu and S.M. Hecht. An Acetate Prodrug of a Pyridinol-Based Vitamin E Analogue. Pharmaceutical Research (2011).

  4. P.M. Arce, O.M. Khdour, R. Goldschmidt, J.S. Armstrong and S.M. Hecht. A Strategy for Suppressing Redox Stress Within Mitochondria. ACS Medicinal Chemistry Letters (2011).

  5. R.C. Nangreave, L.M. Dedkova, S. Chen and S.M. Hecht. A New Strategy for the Synthesis of Bisaminoacylated tRNAs. Organic Letters (2011).

  6. S. Chen, Y. Zhang and S.M. Hecht. p-Thiophenylalanine-Induced DNA Cleavage and Religation Activity of a Modified Vaccinia Topoisomerase IB. Biochemistry (2011).

  7. X. Cai, P.A. Zaleski, A. Cagir and S.M. Hecht. Deglycobleomycin A6 Analogues Modified in the Methylvalerate Moiety. Bioorganic Medicinal Chemistry (2011).

  8. Book chapter: N.J. Rahier, C.J. Thomas, S.M. Hecht. Camptothecin and its Analogues. Antitumor Agents from Natural Sources. CRC Press (2011).

  9. Book chapter: S.M. Hecht. Bleomycin Group Antitumor Agents. Antitumor Agents from Natural Sources. CRC Press (2011).


2010

  1. D. Y. Duveau, P. M. Arce, R. A. Schoenfeld, N. Raghav, G. A. Cortopassi and S. M. Hecht. Synthesis and Characterization of MitoQ and Idebenone Analogues as Mediators of Oxygen Consumption in Mitochondria. Bioorganic Medicinal Chemistry (2010).