News & Events

Energy storehouses in the brain may be source of Alzheimer’s, targets of new therapy

January 23, 2018

Alzheimer’s disease, a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure. The disease is now on an ominous course of expansion, due in part to an aging population, and is poised to become a global health emergency. The enigmatic ailment—first described over 100 years ago—remains the only leading killer without effective treatment, prevention or...

Cutting cancer to pieces: new research on bleomycin

April 30, 2014

A variety of cancers are treated with the anti-tumor agent bleomycin, though its disease-fighting properties remain poorly understood.  In a new study, lead author Basab Roy—a researcher at Arizona State University’s Biodesign Institute—describes bleomycin’s ability to cut through double-stranded DNA in cancerous cells, like a pair of scissors. Such DNA cleavage often leads to cell death in particular types of cancer cells.  The paper is co-authored by professor Sidney...

Hecht named outstanding professor

May 18, 2011

For his leadership in drug design and development, Sidney Hecht was one of nine outstanding ASU faculty members honored with a 2011 Faculty Achievement Award. Dr. Hecht’s current work as director of the Biodesign Institute’s Center for BioEnergetics has the potential of alleviating the suffering of people with mitochondrial dysfunction. People with this rare group of diseases number only in the tens of thousands worldwide, but their conditions are often debilitating and progressive....

Research sheds new light on protein behavior

August 31, 2010

              Proteins play an essential role in virtually every cellular process. They provide actin and myosin for muscles, form the cytoskeleton that maintains a cell’s shape, and carry out innumerable duties critical for immune response, cell signaling and other central functions. A better understanding of protein complexity would be a significant advance in life sciences research, particularly for the study of the mechanisms...