Publications

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2020

  1. Velazquez R, Winslow, W, Mifflin, MA, 2020. “Choline as a prevention for Alzheimer's Disease.” Aging.


2019

  1. Velazquez R, Ferreira E, Knowles S, Fux C, Rodin A, Winslow, W, Oddo S, 2019. “Life-long choline supplementation ameliorates Alzheimer’s disease pathology and associated cognitive deficits by attenuating microglia activation.” Aging cell. 

  2. Velazquez R, Meechoovet B, Ow A, Foley C, Shaw A, Smith B, Oddo S, Hulme C, Dunckley T, 2019. “Chronic Dyrk1 Inhibition Delays the Onset of AD-like Pathology in 3xTg-AD Mice. Mol Neurobiol. Accepted 6/25/19. 

  3. Velazquez R, Ferreira E, Winslow W, Dave N, Piras I, Naymik M, Huentelman M, Tran A, Caccamo A, Oddo S, 2019. “Maternal choline supplementation ameliorates Alzheimer’s disease pathology by reducing brain homocysteine levels across multiple generations”. Mol. Psychiatry. Accepted 01/8/19. 


2018

  1. Belfiore R, Rodin A, Ferreira E, Velazquez R, Branca C, Caccamo A, Oddo S. Temporal and Regional Progression of Alzheimer’s disease-like pathology in 3xTg-AD mice. Aging Cell, 18.

  2. Velazquez R, Tran A, Ferreira E, Turner EC, Oddo S, 2018. “Acute Tau knockdown in the hippocampus of adult mice causes learning and memory deficits”. Aging Cell, 17, 1-12.


2017

  1. Velazquez R, Tran A, Ishimwe E,  Denner L, Dave N, Oddo S, Dineley KT, 2017. “Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer’s disease.” Neurobiol. of Aging 58, 1-13.


2016

  1. Powers BP, Kelly CM, Velazquez R, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ, 2016. “Maternal choline supplementation in a mouse model of Down syndrome: effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring.” Neuroscience 340, 501-514.

  2. Velazquez R, Shaw DM, Caccamo A, Oddo S, 2016. “Pim1 inhibition as a novel therapeutic strategy for Alzheimer’s disease.” Mol Neurodegener. 11, 1 – 14.

  3. Powers BP*, Velazquez R*, Kelley CM, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ, 2016. “Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome.” Brain Struct Funct. 221, 4337-4352.

  4. Kelley CM, Ash JA, Powers BP, Velazquez R, Alldred MJ, Ikonomovic MD, Ginsberg SD, Strupp BJ, Mufson EJ, 2016. “Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome.” Curr Alzheimer’s Res. 1, 84-96.

  5. Strupp BJ, Powers BE, Velazquez R, Ash JA, Kelley CM, Alldred MJ, Strawderman MS, Caudill MA, Mufson EJ, Ginsberg SD, 2016. “Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease.” Curr Alzheimer’s Res. 13, 97-106.


2015

  1. Talboom JS, Velazquez R, Oddo S, 2015. “The mammalian target of rapamycin at the crossroad of aging and Alzheimer’s disease.” Aging and mechanism of disease.


2014

  1. Ash JA*, Velazquez R*, Kelley CM, Powers BE, Ginsberg SD, Mufson EJ, Strupp BJ, 2014. “Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice.” Neurobiol. Dis 70, 32-42.

  2. Kelley CM, Powers BP, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ, 2014. “Maternal choline supplementation differentially alters the basal forebrain cholinergic system of young-adult Ts65Dn and disomic mice.” J Com Neurol.  522, 1390-1410.


2013

  1. Kelley CM, Powers BP, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ, 2013. “Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.” Brain Pathol. 24, 33-44.

  2. Velazquez R, Ash JA, Powers BE, Kelley CM, Strawderman MS, Luscher ZI, Ginsberg SD, Mufson EJ, Strupp BJ, 2013. “Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.” Neurobiol. Dis 58, 92-101.