Associate Research Professor, Biodesign Center for Applied Structural Discovery
The inner sanctum of photosynthesis ----the structure and function of Photosystem I and II-- has been the focus of my research interests since my master thesis and Ph.D. For the past decade, I have had the opportunity to work on crystal structures of various proteins in the broad field of photosynthesis. Membrane proteins are the most interesting and challenging proteins of all. Currently, the Protein Data Bank (PDB) has more than 100,000 structures. In contrast, the number of known membrane protein structures is still around 500 unique structures. Therefore the majority of the most important proteins are still unknown by their structure. The field of membrane protein structure determination is still in the beginning with a clear growing impact to many research topics in chemistry, biochemistry, biology and medicine.