shaydel

Shelley Haydel

Associate Professor
Biodesign Center for Immunotherapy, Vaccines, and Virotherapy

Location: TEMPE

Contact Information
Shelley.Haydel@asu.edu
(480) 727-7234

Education

PhD, University of Alabama-Birmingham, 2000

Research Interests

  1. Biochemical and molecular investigations of mycobacterial two-component regulatory systems, including the PrrAB system that my lab determined is essential for Mycobacterium tuberculosis viability.
  2. Unique M. tuberculosis post-translational modifying enzymes and toxin-antitoxin systems and their role in M. tuberculosis intracellular survival and physiological control. Collaboration with Dr. Mitch Magee, ASU Biodesign Institute Center for Personalized Diagnostics.
  3. Understanding natural antibacterial minerals and customized aluminosilicates and their mechanism of action in order to facilitate chemical synthesis and development of a complementary and inexpensive therapeutic for treating topical infections and promoting wound healing.
  4. Synthesis and development of antibacterial nanosized and nanostructured zeolites as complementary and/or integrative treatments of skin and soft tissue bacterial infections. Collaboration with Dr. Don Seo, ASU School of Molecular Sciences.
  5. Development of a point-of-care (POC) antibiotic susceptibility testing platform. Collaboration with Dr. NJ Tao and Dr. Shaopeng Wang, ASU Biodesign Institute Center for Bioelectronics and Biosensors.
  6. Antibacterial activity of customized antimicrobial peptides and conjugated synthetic peptides against Mycobacterium ulcerans and nontuberculous mycobacteria.
  7. Antibacterial activity of conjugated synthetic peptides against Mycobacterium ulcerans and nontuberculous mycobacteria. Collaboration with Dr. Chris Diehnelt, ASU Biodesign Center for Innovations in Medicine.
  8. Development of novel bioactive sealants which function as a laser-activated nanoglues. Collaboration with Dr. Kaushal Rege, ASU College of Engineering.
  9. Commercial development of antibacterial clays.

Help her team fight infections by donating online: www.asufoundation.org/fighting-infections

https://asu.pure.elsevier.com/en/persons/shelley-haydel/network/

Bio

Shelley Haydel is an infectious disease microbiologist researching new antibiotics to fight resistant infections and how bacteria cause lung infections and wound infections. Her research team studies tuberculosis and other related bacteria, MRSA, and other infectious bacteria that are resistant to antibiotics. She and her research team are also studing how and why these bacteria cause disease in humans so that they can develop new drugs to halt infections.

Professor Haydel and her team are also working with engineers and chemists to create an instrument that takes less than 2 hours to determine if an infection is resistant to antibiotics and to develop skin glues to prevent wound infections.

Help her team fight infections by donating online: www.asufoundation.org/fighting-infections

Haydel is currently the director of the School of Life Sciences Undergraduate Research (SOLUR) program, serving ASU's undergraduate life science students as they begin and advance their research experiences.

Help us help our next-generation scientists by developing their scientific research and professional skills in the SOLUR program: www.asufoundation/solur