pchiu5

Po-Lin Chiu

Asst Professor
School of Molecular Sciences
Faculty Member
Applied Structural Discovery

Location: TEMPE

Contact Information
plchiu@asu.edu
(480) 727-2058

Education

  • Ph.D. Biophysics, University of California-Davis 2009
  • M.EE. Electrical Engineering, National Taiwan University, Taipei, Taiwan 2001
  • B.Sc. Pharmacy, National Taiwan University, Taipei, Taiwan 1999

Research Interests

Our laboratory is interested in the membrane protein structures and lipid-protein interaction.  The current focus is to investigate the interaction between each component of the protein complexes, in the context of the membrane bilayer, that inhibit axonal regeneration.  We are also interested in method development in single-particle cryo-electron microscopy (cryo-EM).  

Bio

Po-Lin Chiu has always been interested in understanding how biological form follows its function. He earned his bachelor's in Pharmacy at National Taiwan University, Taipei, and in addition to the clinical practice, he started to work in the laboratory and study a viral helicase using X-ray crystallography. To expand knowledge, he pursued his master's degree in electrical engineering at National Taiwan University, Taipei, and has the expertise in optics and signal processing. His Ph.D. was then completed in biophysics at the University of California, Davis, focusing on electron microscopy of a bacterial cyclic nucleotide-modulated channel. After graduation, he moved to Harvard Medical School, Boston, as a postdoctoral fellow to study how lipids interact with membrane proteins using cryogenic electron microscopy (cryo-EM). Now at ASU he continues his research investigations on lipid-protein interaction with a focus on the receptor complex of axonal regeneration using the cryo-EM method combined with biophysical and biochemical techniques.