Karie graduated from the University of Kansas with her B.S. in Chemistry and is currently a graduate student in Dr. Petra Fromme's lab in the Biodesign Center for Applied Structural Discovery. She is interested in the role of membrane proteins in the pathogenesis of Borrelia burgdorferi, the causative agent of Lyme disease in the United States. Membrane proteins play key roles in Borrelia's ability to survive in multiple hosts and interact with the host immune system, making them optimal targets for new drugs and vaccines. Her project is focused on expressing and purifying several B. burgdorferi integral membrane protein targets for structural and functional studies.