Publications
In Process
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Y. Xu, S. Jiang, C. Simmons, R.P. Narayanan, F. Zhang, A.-M. Aziz, H. Yan, N. Stephanopoulos*, “Tunable nanoscale cages from self-assembling DNA and protein building blocks” (in preparation)
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T. MacCulloch, A. Buchberger, N. Stephanopoulos*, “Peptide-oligonucleotide conjugates: synthesis, applications, and emerging opportunities” Org. Biomol. Chem. (invited review, in revision)
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A. Stelson, M. Liu, C. Little, C. Long, N. Orloff, N. Stephanopoulos*, J. Booth*, “Labelfree detection of conformational changes in switchable DNA nanostructures with microwave
2018
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M. Liu, S. Jiang, O. Loza, N.E. Fahmi, P. Šulc, N. Stephanopoulos*, “Rapid photo-actuation of a DNA nanostructure using an internal photocaged trigger strand” Angew. Chem. Int. Ed. 2018, 57, 9341-9345.
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N. Stephanopoulos*, R. Freeman*, “DNA-based materials as self-assembling scaffolds for interfacing with cells” (invited book chapter), “Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine, 1st Edition” 2018, pp. 157-175. (Elsevier)
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L. Avolio, D. Sipes, N. Stephanopoulos, S. Sur*, “Recreating stem-cell niches using selfassembling biomaterials” (invited book chapter), “Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine, 1st Edition” 2018, pp. 421-454. (Elsevier)
2017
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C. Simmons, F. Zhang, T. MacCulloch, N.E. Fahmi, N. Stephanopoulos, Y. Liu, N. Seeman, H. Yan*, “Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals” J. Am. Chem. Soc. 2017, 139, 11254-11260.
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D. Varun, G.R. Srinivaan, Y.-H. Tsai, H.-J. Kim, J. Cutts, F. Petty, R. Merkley, N. Stephanopoulos, D. Dolezalova, M. Marsala, D.A. Brafman*, “A Robust VintronectinDerived Peptide for the Scalable Long-term Expansion and Neuronal Differentiation of Human Pluripotent Stem Cell (hPSC)-derived Neural Progenitor Cells (hNPCs)” ActaBiomater. 2017, 48, 120-130.
2015
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J.J. Greene, M.T. McClendon, N. Stephanopoulos, S.I. Stupp, C.-P. Richter, “A Bioengineered Peptide Amphiphile Nanofiber Neurograft for Facial Nerve Repair: A Comparison to Autografting using Evoked Electromyography (EMG)” (in preparation)
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F. Tantakitti, S. Sur, D. Carvajal, R.H. Zha, N. Stephanopoulos, B.R. Olsen, S.I. Stupp, “Orthogonal control of bioactive diffusible and matrix signals on a cell microcarrier” (in preparation)
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C.J. Newcomb1, S. Sur, J.M. Yu, S.S. Lee, N. Stephanopoulos, J.L. Kinol, S.I. Stupp, “Supramolecular nanofibers augment growth factor signaling by increasing lipid raft mobility” (in preparation)
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Z.A. Sayed, A.M. Fernando, E.J. Berns, N. Stephanopoulos, J.A. Kessler, S.I. Stupp, A.J. Matsuoka, “Re-creating a ‘stem cell niche’ in the inner ear and internal auditory canal using nanofiber based peptide amphiphile gels” (submitted)
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R. Freeman*, N. Stephanopoulos*, S. Sur, J. Boekhoven, S.S. Lee, S.I. Stupp, “Instructing cells with programmable DNA-peptide hybrids” (submitted) (* co-first authors)
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C. Rubert-Perez, N. Stephanopoulos, S.S. Lee, S. C. Newcomb, Sur, S.I. Stupp, “The Powerful Functions of Peptide-Based Bioactive Matrices for Regenerative Medicine” (invited review) Ann. Biomed. Eng. 2015, 43, 501-514.
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N. Stephanopoulos, R. Freeman, H.N. Scheler, S. Sur, S. Jeong, F. Tantakitti, J.A. Kessler, S.I. Stupp, “Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons” Nano Lett. 2015, 15, 603-609.
2014
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A. Li, A. Hokugo, A. Yalom, E.J. Berns, N. Stephanopoulos, M.T. McClendon, L.A. Segovia, I. Spigelman, S.I. Stupp, R. Jarrahy., “A bioengineered peripheral nerve construct using aligned peptide amphiphile nanofibers” Biomaterials 2014, 35, 8780-8790.
2013
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J. Sack, N. Stephanopoulos, D.C. Austin, M.B. Francis, J.S. Trimmer, “Antibody-guided photoablation of voltage-gated potassium channels” J. Gen. Physiol. 2013, 142, 315-324.
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N. Stephanopoulos, J.H. Ortony, S.I. Stupp, “Self-Assembly for the Synthesis of Functional Biomaterials” (invited review) Acta Materialia (special Diamond Jubilee Issue), 2013, 61, 912-930.
2012
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N. Stephanopoulos, M.B. Francis, “Making New Materials from Viral Capsids” (invited book chapter) “Polymer Science: A Comprehensive Reference, 1st Edition” 2012, Vol. 9, pp. 247-266. (Elsevier)
2011
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N. Stephanopoulos, M.B. Francis, “Choosing an Effective Protein Bioconjugation Strategy.” (invited review) Nat. Chem. Biol. 2011, 7, 876-884.
2010
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P.G. Holder, D.T. Finley, N. Stephanopoulos, R. Walton, D.S. Clark, M.B. Francis, “Dramatic Thermal Stability of Virus-Polymer Conjugates in Hydrophobic Solvents” Langmuir 2010, 26, 17383–17388.
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N. Stephanopoulos, G.J. Tong, S.C. Hsiao, M.B. Francis, “Dual-Surface Modified Virus Capsids for Targeted Delivery of Photodynamic Agents to Cancer Cells” ACS Nano, 2010, 4, 6014-6020.
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N. Stephanopoulos*, M. Liu*, G.J. Tong, Z. Li, Y. Liu, H. Yan, M.B. Francis, “Immobilization and One-Dimensional Arrangement of Virus Capsids with Nanoscale Precision Using DNA Origami” Nano Lett. 2010, 10, 2714-2720. (* co-first authors)
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R.A. Miller, N. Stephanopoulos, J.M. McFarland, A.S. Rosko, P.L. Geissler, M.B. Francis, “The Impact of Assembly State on the Defect Tolerance of TMV-based Light Harvesting Arrays” J. Am. Chem. Soc. 2010, 132, 6068-6074.
2009
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N. Stephanopoulos, Z.M. Carrico, M.B. Francis, “Nanoscale Integration of Sensitizing Chromophores and Porphyrins Using Bacteriophage MS2” Angew. Chem. Int. Ed. 2009, 121, 9662-9666.
2005
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N. Stephanopoulos, E.O.P. Solis, G. Stephanopoulos, “Nanoscale process systems engineering: Toward molecular factories, synthetic cells, and adaptive devices” (invited perspective) AIChE J. 2005, 51, 1858-1869.