What if We Could Harness the Capabilities of Our Own Immune System to Cure Cancer?

What if We Could Harness the Capabilities of Our Own Immune System to Cure Cancer?

May 17, 2017

Address

727 E. Tyler St.
Tempe, AZ 85287

Location

Biodesign Institute, Auditorium B105

Date and Time

May 31, 2017, 12:00 pm (Length: 1 hour 0 minutes)

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Cheryl Selinsky, Ph.D., Vice President, Research Operations, Parker Institute for Cancer Immunotherapy

Immunotherapy harnesses your body’s own defenses to fight cancer. It takes the always-on defense of your own immune system and trains it to recognize cancer cells and to kill them. Dramatic responses seen in metastatic melanoma patients treated with immunotherapy spurred a renewed invigoration of the field and the promise it holds to offer robust and durable responses in many cancers. Selinsky will provide an overview of the Parker Institute’s consortium model and scientific agenda, highlighting a clinical trial using CRISPR-Cas9 gene editing of T cell receptors for adoptive cell therapy and studies to uncover the mechanisms of resistance to checkpoint blockade and the concomitant incidence of autoimmunity observed in some patients treated with this immunotherapy. Discussions also will include a new approach to move toward tailored, personalized vaccines for cancer using algorithms to identify the mutated proteins in an individual’s tumor.