Targeting Drug Delivery to Treat Central Nervous System Disease

Targeting Drug Delivery to Treat Central Nervous System Disease

February 21, 2018

Address

727 E. Tyler St.
Tempe, AZ 85287

Location

Biodesign Institute, Auditorium

Date and Time

February 28, 2018, 12:00 pm (Length: 1 hour 0 minutes)

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Rachael Sirianni, Ph.D., Assistant Professor, Neurobiology, Barrow Neurological Institute

A universal nanocarrier that is capable of delivering any drug specifically to a single tissue site with minimal off-target effects has been the promise of drug delivery. However, a true "magic bullet" drug-delivery system has yet to be translated to human use. What would it take to design nanoparticles for targeted drug delivery that could reach the clinic? Rachael Sirianni will discuss new approaches for improving drug delivery and function in the brain and spinal cord. This work will focus on the importance of tracking polymer fate within the body, translational drug discovery and development, and early application in models of human disease, including neuro-oncology and neurodegeneration.