Gut microbe research featured in Nature

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Gut microbe research featured in Nature

May 2, 2014

May 2, 2014

In a new Nature magazine feature article, science writer Sarah Deweerdt interviews leading researchers who are unravelling the fascinating relationship between diet, gut microbes and human diseases. Among those featured is research led by Rosa Krajmalnik-Brown, whose team examines the links between gut microbes, obesity, and more recently, an intriguing connection with autism. 

Deweerdt writes:

In an ongoing study, [Bruce] Rittmann and Krajmalnik-Brown are analysing the gut microbiota of up to 40 inpiduals several years after gastric bypass surgery to try to identify differences in the microbiota of successful and unsuccessful patients.

The team also plans to follow about ten new gastric bypass patients to track the changes in their gut microbiota after the surgery. “We’re trying to find a biomarker,” Krajmalnik-Brown says. “That would be really great if we could increase the success rate of surgery just by knowing the characteristics of the gut microbiota that are linked to success.”

The complex relationship between gut microbes and human health is summarized in the following infographic:

The gut microbiota research projects are also a prime example of the large team, collaborative nature of Biodesign research, and how we carry out clinical studies. The research team draws on a partnership with Mayo Clinic gastroenterologist Dr. John DiBiase, M.D., as well as other centers at Biodesign, including: 

Team:  Daewook Kang, Zehra Esra Ilhan, Kapila Patel

Collaborators:  Andrew K. Marcus, Joshua LaBaer, Jin Gyoon Park, James Adams, Bruce Rittmann, John DiBaise, Sarkis K. Mazmanian, Rob Knight, Jack Gilbert, Catherine Lozupone, Greg Caporaso, Matthew Sullivan


Written by: Joe Caspermeyer