Genome Evolution and Adaptation in Hybrids

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Genome Evolution and Adaptation in Hybrids

November 15, 2017

Address

727 E. Tyler St.
Tempe, AZ 85287

Location

Biodesign Institute, Auditorium

Date and Time

November 27, 2017, 1:30 pm (Length: 1 hour 0 minutes)

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Presented by Caiti Heil, Ph.D., Senior Fellow University of Washington, Genome Sciences Department

Caiti Heil explores the evolutionary processes that create and maintain genetic variation, most recently, investigating how hybridization between different populations or species represents a potential evolutionary pathway for rapid adaptation to selective pressures. When two divergent genomes merge, new combinations of alleles are introduced simultaneously, acting as an instantaneous and abundant source of genetic variation. Heil utilize hybrids from the Saccharomyces yeast clade to understand if and how this variation aids a population in adaptation to novel environments. By creating de novo hybrids and evolving them for hundreds of generations in the laboratory, she demonstrates how mutations like loss of heterozygosity and transposable elements shape the genomes of hybrid populations, and how the environment influences the persistence of hybrid lineages.

Co-hosts: Biodesign Center for Mechanisms of Evolution and the School of Life Sciences