Decoding Genome Evolution to Enhance Studies of Microbes and Communities

Decoding Genome Evolution to Enhance Studies of Microbes and Communities

January 23, 2020

Address

727 E. Tyler St.
Tempe, AZ 85281

Location

Biodesign Institute, AL1-10/14

Date and Time

January 27, 2020, 1:30 pm (Length: 1 hour 0 minutes)

iCal Download

Qiyun Zhu, PhD, Postdoctoral Scholar, University of California, San Diego

The art of microbiomics is morphing from amplicon toward whole-genome and metagenome studies, hence requiring novel methods and resources to couple with the rapidly growing volume and complexity of data. I strive to build a reference which accurately defines the evolutionary relationships among microbial genomes. My work advances the state-of-the-art along three dimensions: larger representation of biodiversity, more comprehensive use of whole-genome information, and improved methodology for harnessing the power of big data. The result provides a significantly updated view of the microbial tree of life. The product, publicly available at https://biocore.github.io/wol/, not only expands knowledge but also enables evolution-guided microbiome research, together with multiple novel bioinformatics tools and protocols. Its strength has been evident in multiple studies. The entire project, codenamed “Web of Life”, will continue to expand and benefit the microbiome research community.

Hosted by the Biodesign Center for Fundamental and Applied Microbiomics.