Publications

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2016

  1. Lilly CL, Villa NY, et al.: Ex vivo oncolytic virotherapy with myxoma virus arms multiple allogeneic bone marrow transplant leukocytes to enhance graft-vs-cancer. Mol Ther Oncolytics, 2016. Paper # MTO-00119, OMTO 8 (Accepted, In Press).

  2. Villa NY, Rahman MM, McFadden G, Cogle CR. Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies. Viruses. 2016, 8(3):E85. PMID: 27011200.

  3. Villa NY, Bais S, Chan WM, Meacham AM, Wise E, Rahman MM, Moreb JS, Rosenau EH, Wingard JR, McFadden G, Cogle CR. Ex vivo virotherapy with myxoma virus does not impair hematopoietic stem and progenitor cells. Cytotherapy, 2016. 18(3):465-4880. PMID: 26857235.


2015

Villa NY, Wasserfall CH, Meacham AM, Wise E, Chan W, Wingard JR, McFadden G, Cogle CR. Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to cancer cells. Blood. 2015, 125(24):3778-3788. PMID: 25904246.


2014

Cordova-Sintjago TC, Villa NY, Fang LJ, Booth RG Aromatic interactions impact ligand binding and function at serotonin 5-HT2C G protein-coupled receptors: Receptor homology modeling, ligand docking, and molecular dynamics results validated by experimental studies. Mol Phys. 2014, 112(34):398-407. PMID: 24729635.


2012

Cordoba-Sintjago TC, Villa NY, Canal CE, Fang LJ, Booth RG. Serotonin 5-HT2C G Protein-Coupled Receptor Homolog Model from the b2 Adrenoceptor Structure: Ligand Docking and Mutagenesis Studies. Int J of Qant Chem. 2012, 112(1): doi: 10.1002/qua.23231. PMID: 24244046.


2011

  1. Canal CE, Cordova-Sintjago TC, Villa NY, Fang LJ, Booth RG. Drug discovery targeting human 5HT(2C) receptors: residues S3.36 and Y7.43 impact ligand-binding pocket structure via hydrogen bond formation. Eur J Pharmacol. 2011, 673(1-3):1-12. 
  2. Villa NY, Moussatche P, Chamberlin SG, Kumar A, Lyons TJ. Phylogenetic and preliminary phenotypic analysis of yeast PAQR receptors: potential antifungal targets. J Mol Evol. 2011, 73(34):134-52. 

2010

Villa NY, Bartee E, Mohamed MR, Rahman MM, Barrett JW, McFadden G. Myxoma and vaccinia viruses exploit different mechanisms to enter and infect human cancer cells. Virology. 2010, 401(2):266-79. 


2009

  1. Van Vliet K, Mohamed MR, Zhang L, Villa NY, Werden SJ, Liu J, McFadden G. Poxvirus proteomics and virus-host protein interactions. Microbiol Mol Biol Rev. 2009, 73(4):730-49. 
  2. Zhang L, Villa NY, Rahman MM, Smallwood S, Shattuck D, Neff C, Dufford M, Lanchbury JS, Labaer J, McFadden G. Analysis of vaccinia virus-host protein-protein interactions: validations of yeast two-hybrid screenings. J Proteome Res. 2009, 8(9):4311-8.
  3. Kupchak BR, Garitaonandia I, Villa NY, Smith JL, Lyons TJ. Antagonism of human adiponectin receptors and their membrane progesterone receptor paralogs by TNFalpha and a ceramidase inhibitor. Biochemistry. 2009, 48(24):5504-6. 
  4. Zhang L, Villa NY, McFadden G. Interplay between poxviruses and the cellular ubiquitin/ubiquitinlike pathways. FEBS Lett. 2009, 583(4):607-14.
  5. Villa NY, Kupchak BR, Garitaonandia I, Smith JL, Alonso E, Alford C, Cowart LA, Hannun YA, Lyons TJ. Sphingolipids function as downstream effectors of a fungal PAQR. Mol Pharmacol. 2009, 75(4):866-75

2008

Kupchak BR, Villa NY, Kulemina LV, Lyons TJ. Dissecting the regulation of yeast genes by the osmotin receptor. Biochem Biophys Res Commun. 2008, 374(2):210-3.


2007

Kupchak BR, Garitaonandia I, Villa NY, Mullen MB, Weaver MG, Regalla LM, Kendall EA, Lyons TJ. Probing the mechanism of FET3 repression by Izh2p overexpression. Biochim Biophys Acta. 2007, 1773(7):1124-32.


2004

Lyons TJ, Villa NY, Regalla LM, Kupchak BR, Vagstad A, Eide DJ. Metalloregulation of yeast membrane steroid receptor homologs. Proc Natl Acad Sci U S A. 2004, 101(15):5506-11.