Publications

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2019

  1. Kotagama K, Schorr AL, Steber HS, Mangone M. miRNA activity contributes to accurate RNA splicing in C. elegans intestine and body muscle tissues. BioRxiv. 2019 January;

  2. Kotagama K, Schorr AL, Steber HS, Mangone M. ALG-1 Influences Accurate mRNA Splicing Patterns in the Caenorhabditis elegans Intestine and Body Muscle Tissues by Modulating Splicing Factor Activities. Genetics. 2019 Jul;212(3):931-951. doi: 10.1534/genetics.119.302223. Epub 2019 May 9. PubMed PMID: 31073019; PubMed Central PMCID: PMC6614907.

  3. Hrach HC, Mangone M. miRNA Profiling for Early Detection and Treatment of Duchenne Muscular Dystrophy. Int J Mol Sci. 2019 Sep 19;20(18). doi: 10.3390/ijms20184638. Review. PubMed PMID: 31546754; PubMed Central PMCID: PMC6769970.

  4. Steber HS, Gallante C, O'Brien S, Chiu PL, Mangone M. The C. elegans 3' UTRome v2 resource for studying mRNA cleavage and polyadenylation, 3'-UTR biology, and miRNA targeting. Genome Res. 2019 Nov 19;. doi: 10.1101/gr.254839.119. [Epub ahead of print] PubMed PMID: 31744903.

2017

  1. Blazie SM, Geissel HC, Wilky H, Joshi R, Newbern J, Mangone M. Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Caenorhabditis elegans Somatic Tissues. Genetics. 2017 Jun;206(2):757-774. doi: 10.1534/genetics.116.196774. Epub 2017 Mar 27. PubMed PMID: 28348061; PubMed Central PMCID: PMC5499184.

  2. Walter JM, Le HH, Linse A, Godlove VA, Nguyen TD, Kotagama K, Lynch A, Rawls A and Mangone M (2017) Evolutionary patterns of metazoan microRNAs reveal targeting principles in the let-7 and miR-10 families Genome Res. (2017) 27: 53-63

2016

  1. Wallace RG, Twomey LC, Custaud MA, Moyna N, Cummins PM, Mangone M, Murphy RP. Potential Diagnostic and Prognostic Biomarkers of Epigenetic Drift within the Cardiovascular Compartment. Biomed Res Int. 2016;2016:2465763. doi: 10.1155/2016/2465763. Epub 2016 Jan 28. Review. PubMed PMID: 26942189; PubMed Central PMCID: PMC4749768.

  2. Hutchins ED, Eckalbar WL, Wolter JM, Mangone M, Kusumi K. Differential expression of conserved and novel microRNAs during tail regeneration in the lizard Anolis carolinensis. BMC Genomics. 2016 May 5;17:339. doi: 10.1186/s12864-016-2640-3. PubMed PMID: 27150582; PubMed Central PMCID: PMC4858913.

  3. Wolter JM, Le HH, Linse A, Godlove VA, Nguyen TD, Kotagama K, Lynch A, Rawls A, Mangone M. Evolutionary patterns of metazoan microRNAs reveal targeting principles in the let-7 and miR-10 families. Genome Res. 2017 Jan;27(1):53-63. doi: 10.1101/gr.209361.116. Epub 2016 Dec 7. PubMed PMID: 27927717; PubMed Central PMCID: PMC5204344.

2015

  1. Blazie SM, Babb C, Wilky H, Rawls A, Park JG, Mangone M. Comparative RNA-Seq analysis reveals pervasive tissue-specific alternative polyadenylation in Caenorhabditis elegans intestine and muscles. BMC Biol. 2015 Jan 20;13:4. doi: 10.1186/s12915-015-0116-6. PubMed PMID: 25601023; PubMed Central PMCID: PMC4343181.

  2. Wolter JM, Kotagama K, Babb CS, Mangone M. Detection of miRNA Targets in High-throughput Using the 3'LIFE Assay. J Vis Exp. 2015 May 25;(99):e52647. doi: 10.3791/52647. PubMed PMID: 26066857; PubMed Central PMCID: PMC4542967.

  3. Kotagama K, Chang Y, Mangone M. miRNAs as Biomarkers in Chronic Myelogenous Leukemia. Drug Dev Res. 2015 Sep;76(6):278-85. doi: 10.1002/ddr.21266. Epub 2015 Aug 18. Review. PubMed PMID: 26284455; PubMed Central PMCID: PMC4758911.

  4. Kotagama K, Babb CS, Wolter JM, Murphy RP, Mangone M. A human 3'UTR clone collection to study post-transcriptional gene regulation. BMC Genomics. 2015 Dec 9;16:1036. doi: 10.1186/s12864-015-2238-1. PubMed PMID: 26645212; PubMed Central PMCID: PMC4673713.

2014

  1. Wolter JM, Kotagama K, Pierre-Bez AC, Firago M, Mangone M. 3'LIFE: a functional assay to detect miRNA targets in high-throughput. Nucleic Acids Res. 2014;42(17):e132. doi: 10.1093/nar/gku626. Epub 2014 Jul 29. PubMed PMID: 25074381; PubMed Central PMCID: PMC4176154.