Publications

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2015

  1. Mills, J.H.; Sheffler, W.; Ener, M.E.; Oberdorfer, G.; Pereira, J.H.; Banumathi, S.; Zwart, P.; Baker, D.; “A computationally designed high-affinity homotrimeric metalloprotein containing a metal chelating non-canonical amino acid” Manuscript in preparation.

  2. Mills, J.H.*; Pearson, A.D.*; Song, Y.; Nasertorabi, F.; Han, G.W.; Baker, D.; Stevens, R.C.; Schultz, P.G. “Crystal Structure of a Kinetically Persistent Transition State in a Computationally Designed Protein Bottle” Science, 2015, 347, 863. (equal authorship contributions for JHM and ADP)


2013

Mills, J.H.;  Khare, S.D.; Bolduc, J.M.; Forouhar, F.; Mulligan, V.K.; Lew, S.; Seetharaman, J.; Tong, L.; Stoddard, B.L.; Baker, D. “Computational Design of Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy” Journal of the American Chemical Society 2013, 135 (36), 13393.


2012

  1. Gordon, S.R.; Stanley, E.J.; Wolf, S.; Toland, A.; Wu, S.J.; Hadidi, D.; Mills, J.H.; Baker, D.; Pultz, I.S.; Siegel, J.B.;  “Computational Design of an a-Gliadin Peptidase” Journal of the American Chemical Society 2012, 134 (50), 20513.

  2. Harger, M.; Zheng, L.; Moon, A.; Ager, C.; An, J.H.; Choe, C.; Lai, Y.; Mo, B.; Zong, D.; Smith, M.D.; Egbert, R.G.; Mills, J.H.; Baker, D.; Pultz, I.S.; Siegel, J.B. “Expanding the Product Profile of a Microbial Alkane Biosynthetic Pathway” ACS Synthetic Biology 2012, 2 (1), 59.


2011

Wu, S.J.; Eiben, C.B.; Carra, J.H.; Huang, I.; Zong, D.; Liu, P.; Wu, C.T.; Nivala, J.; Dunbar, J.; Huber, T.; Senft, J.; Schokman, R.; Smith, M.D.; Mills, J.H.; Friedlander, A.M.; Baker, D.; Siegel, J.B.; “Improvement of a Potential Anthrax Therapeutic by Computational Protein Design” Journal of Biological Chemistry 2011, 286 (37), 32586.


2009

  1. Mills, J.H.; Lee, H.S; Liu, C.C.; Wang, J.; Schultz, P.G. “A Genetically Encoded Direct Sensor of Antibody-Antigen Interactions” ChemBioChem 2009, 10 (13), 2162.

  2. Liu, C.C.; Mack A.V.; Brustad E.M.; Mills J.H.; Groff D.; Smider V.V.; Schultz P.G. “Evolution of Proteins with Genetically Encoded ‘Chemical Warheads’” Journal of the American Chemical Society 2009, 131 (28), 9616.


2008

Liu, C.C.; Mack A.V.; Tsao M.L.; Mills, J.H.; Lee, H.S.; Choe, H.; Farzan, M.; Schultz, P.G.; Smider, V.V. “Protein Evolution with an Expanded Genetic Code” Proceedings of the National Academy of Sciences U.S.A. 2008, 105 (46), 17688.


2005

Kavrakova, I.K.; Mills, J.H.  “Lewis Acid Promoted Kharasch-type Additions of 3-bromoacetyl-2-oxazolidinone to Cycloalkenes” Journal of Chemical Research 2005, 2005 (1), 59.


2004

Yin, J.; Mills, J.H.; Schultz, P.G.  “A Catalysis Based Selection for Peroxidase Antibodies with Increased Activity.” Journal of the American Chemical Society 2004, 126 (10), 3006.


2003

Pratt, D.A.; Mills, J.H.; Porter, N.A. “Theoretical Calculations of Carbon—Oxygen Bond Dissociation Enthalpies of Peroxyl Radicals Formed in the Autoxidation of Lipids.” Journal of the American Chemical Society 2003, 125 (19), 5801.


2001

Orihuela, C.J.; Mills, J.H.; Robb, C.W.; Wilson, C.J.; Watson, D.A.; Niesel, D.W. “Streptococcus pneumoniae PstS Production is Phosphate Responsive and Enhanced During Growth in the Murine Peritoneal Cavity.”Infection and Immunology 2001, 69 (12), 7565.