Founding Center Director, ASU-Banner Neurodegenerative Disease Research Center
Jeffrey Kordower is the founding director of the ASU-Banner Neurodegenerative Disease Research Center and endowed chair as The Charlene and J. Orin Edson Distinguished Director at the Biodesign Institute at ASU. He has been a pioneer in the field of neural transplantation techniques and his pathbreaking investigations into the underpinnings of neurodegenerative disease have made him a leader in the field. His interests include the study of gene and stem cell therapies, disease pathogenesis including the morphological and molecular changes during the course of neurodegeneration, learning and memory, and aging.
Kordower employs gene therapy, neural transplantation and the discovery of molecular changes to his research of Alzheimer's, Parkinson's and Huntington's diseases. He has led numerous gene and cell therapy preclinical studies that have gone on to clinical trials. His findings have included the first demonstration that fetal dopaminergic grafts can survive, innervate, and form synapses in patients with Parkinson's disease, and he and his collaborators were the first to show that long-term grafts in such patients can form Lewy bodies. He has also been a pioneer in the field of neural transplantation techniques.