News & Events

In Africa, a deadly Salmonella strain takes hold

September 8, 2015

Salmonella is an infectious agent with many faces, appearing in a multitude of strains affecting animals and humans. A distinct form of the bacterial invader has emerged in sub-Saharan Africa and is responsible for severe epidemic outbreaks. Its unusual characteristics—including a high rate of lethality, invasiveness, atypical symptomatolgy and resistance to multiple antibiotics—are of rising concern. In a new study, Cheryl Nickerson and her colleagues at the Biodesign Institute at...

New research probes key component of the immune system

June 24, 2015

In the immune system, CD8 T cells perform a dual role, guarding against infection and mediating the progression of disease. Like acutely sensitive watchmen, they patrol the bloodstream, ever on-guard for suspicious activity. Such cells are said to be cytotoxic— lethal to their enemies, which include virally or bacterially infected cells as well as cancer cells.  While CD8 T cell activity provides an indispensible line of defense against infection, it can be a double-edged sword. CD8 T...

Sex, Evolution and Disease

June 22, 2015

Presented by Melissa Wilson Sayres, Ph.D., Assistant Professor, Biodesign Institute’s Center for Evolution and Medicine This is a Spirit of the Senses salon. Members and Biodesign employees and their guests are welcome. More information

Nature microgravity journal takes flight

June 5, 2015

A new on-line, open-access, peer-reviewed journal focusing on multidisciplinary research performed in microgravity and Earth-based microgravity analogue environments has taken flight.   The first issue of npj Microgravity, a joint project between the Biodesign Institute at Arizona State University (ASU) and the Nature Publishing Group with support from NASA, is now available.  Designed to be the premier journal covering research that both enables and is enabled by spaceflight, this...

Engineering new lungs

May 27, 2015

According to the World Health Organization, chronic obstructive pulmonary disease (COPD) currently affects more than 64 million people worldwide and is poised to become the third leading cause of mortality by 2030. A hallmark of COPD is scarring of the lungs, a condition called pulmonary fibrosis, which impacts breathing. There is no cure for the condition or ability to repair the scarring that has occurred. Thus, in the late stages of lung disease, just one remedy exists: organ...

ASU professor Charles Arntzen named Fast Company’s Most Creative Person in Business

May 11, 2015

Arizona State University Biodesign Institute researcher Charles Arntzen has been chosen as the No. 1 honoree among Fast Company’s annual “100 Most Creative People in Business” for his leadership role in developing ZMapp, a therapeutic produced in tobacco to fight Ebola. “I never anticipated we would get ZMapp into human testing for another three or four years, and suddenly, the urgency of the situation in West Africa was upon us,” said Arntzen, who attended a star-studded Fast...

Ebola Therapy

May 1, 2015

Presented by Charles Arntzen, Ph.D., Regents' Professor and Florence Ely Nelson Presidential Chair, Biodesign’s Center for Infectious Diseases and Vaccinology This is a Spirit of the Senses salon. Members and Biodesign employees and their guests are welcome.

Anivax licenses Biodesign Institute food safety vaccine technology from Arizona Technology Enterprises

April 22, 2015

Anivax and Arizona Technology Enterprises (AzTE) announced today an agreement to license several technologies developed by professor Roy Curtiss III at the Biodesign Institute at Arizona State University for the development of Anivax’s revolutionary Campylobacter food safety vaccine. The vaccine is designed to be administered to poultry, reducing colonization by the bacteria and ultimately lowering the incidence of human disease. The licensed technologies include specialized approaches for...

Salmonella shows promise as a cancer therapeutic

April 14, 2015

Arizona State University Biodesign Institute scientist Roy Curtiss is making international headlines for a promising new adaptation of his team's expertise in using genetically modifying Salmonella to aid human health----this time, in the fight against cancer.  Salmonella, the bacteria commonly known for causing food poisoning, may be genetically modified to kill cancer cells without causing harm to patients, according to Curtiss, who directs the Center for Infectious Diseases and...

Study examines bacterial threat to chickens and humans

February 9, 2015

Within 40 hours of birth, E. coli bacteria colonize an infant’s gastrointestinal tract, taking up lifelong residence. There, they perform various housekeeping roles, assisting with food absorption, producing the vitamin K2, and defending against harmful bacteria attempting to invade the intestine. Not all E. coli however are welcome guests. Some bacterial strains, known as ExPEC (for extra intestinal pathogenic E. coli) are responsible for a range of illnesses in humans, including neonatal...