Publications

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Recent Publications

  1. Mathew LG, Herbst-Kralovetz M, Mason HS. Norovirus Narita 104 virus-like particles expressed in Nicotiana benthamiana induce serum and mucosal immune responses. Biomed. Res. International: Plant-made Biologics (2014).
  2. Moon K-B, Kang Y-J, Kim M, Kang S, Mason HS, Jeon J-H, Kim H-S. Overexpression and self-assembly of virus-like particles in N. benthamiana by a single-vector DNA replicon system. Appl. Microbiol. Biotechnol (2014).
  3. Rattanapisit K, Bhoo SH, Hahn TR, Mason HS, Phoolcharoen W. Rapid transient expression of cholera toxin B subunit (CTB) in Nicotiana benthamiana. In Vitro Cell. Devel. Biol. – Plant (2013).

2012

  1. Miller T, Fanton M, Nickelson S, Mason H, Webb S. Safety and immunogenicity of bacterial and tobacco plant cell line derived recombinant native and mutant Escherichia coli heat-labile toxin in chickens. Avian Pathol. (2012).

  2. Book chapter: Mason HS, Herbst-Kralovetz MM. Plant-derived antigens as mucosal vaccines. Current Topics in Microbiology and Immunology , Mucosal Vaccines: Modern Concepts, Strategies, and Challenges. Springer (2012).


2011

  1. Chen Q, He J, Phoolcharoen W, Mason HS. Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants. Human Vaccines (2011).

  2. Mathew LG, Maloney B, Takeda N, Mason HS. Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants.Plant Mol Biol. (2011).

  3. Mathew LG, Maloney B, Takeda N, Mason HS. Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants.Plant Mol Biol. (2011).

  4. Phoolcharoen W, Bhoo SH, Lai H, Ma J, Arntzen CJ, Chen Q, Mason HS. Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. Plant Biotechnol. J. (2011).

  5. Phoolcharoen W, Dye JM, Kilbourne J, Piensook K, Pratt WD, Arntzen CJ, Chen Q, Mason HS, Herbst-Kralovetz MM. A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc. Natl. Acad. Sci. USA (2011).

  6. Pinkhasov J, Alvarez ML, Rigano MM, Piensook K, Larios D, Pabst M, Grass J, Mukherjee P, Gendler SJ, Walmsley AM, Mason HS. Recombinant plant-expressed tumor-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice. Plant Biotechnol. J.(2011).


2010

  1. Daskalova SM, Radder JE, Cichacz ZA, Olsen SH, Tsaprailis G, Mason H, Lopez LC. Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation. BMC Biotechnol. (2010).

  2. Herbst-Kralovetz M, Mason HS (corresponding author), Chen Q. Norwalk virus-like particles as vacines. Expert Rev. Vaccines (2010).

  3. Huang Z, Phoolcharoen W, Lai H, Piensook K, Cardineau G, Zeitlin L, Whaley KJ, Arntzen CJ, *Mason HS, *Chen Q. High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system. Biotechnol. Bioeng. (2010).

  4. Martinez CA, Topal E, Giulietti AM, Talou JR, Mason HS. Exploring different strategies to express Dengue virus envelope protein in a plant system. Biotechnol. Lett. (2010).

  5. Pinkhasov J, Alvarez ML, Pathangey LB, Tinder TL, Mason HS, Walmsley AM, Gendler SJ, Mukherjee P. Analysis of a cholera toxin B subunit (CTB) and human mucin 1 (MUC1) conjugate protein in a MUC1-tolerant mouse model. Cancer Immunol Immunother (2010).

  6. Book chapter: Santi L, Mason HS. Plants as biofactories for vaccine production. Encyclopedia of Biotechnology in Agriculture and Food. Taylor & Francis (2010).


2009

  1. Del Prete G, Santi L, Andrianaivoarimanana V, Amedei A, Domarle O, D' Elios MM, Arntzen CJ, Rahalison L, Mason HS. Plant-derived recombinant F1, V, and F1-V fusion antigens of Yersinia pestis activate human cells of the innate and adaptive immune system. Int J Immunopathol Pharmacol (2009).

  2. Huang Z, Chen Q, Hjelm B, Arntzen C, Mason H. A DNA replicon system for rapid high-level production of virus-like particles in plants.Biotechnol. Bioeng. (2009).

  3. Webster DE, Wang L, Mulcair M, Ma C, Santi L, Mason HS, Wesselingh SL, Coppel RL. Production and characterisation of an orally immunogenic Plasmodium antigen in plants using a virus-based expression system. Plant Biotechnol. J. (2009).


2008

  1. Huang Z, LePore K, Elkin G, Thanavala Y, Mason HS. High-yield rapid production of hepatitis B surface antigen in plant leaf by a viral expression system. Plant Biotechnol. J. (2008).

  2. Luca Santi, Lance Batchelor, Zhong Huang, Brooke Hjelm, Jacquelyn Kilbourne, Charles Arntzen, Qiang Chen, Hugh Mason. An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles. Vaccine (2008).


2007

  1. Santi, L, Mason, Hugh S. Vaccines Produced in Transgenic Plants. Encyclopedia of Biotechnology in Agriculture and Food (2007).

  2. J Van Eck, B Conlin, D Garvin, Hugh Mason, D Navarre, C Brown. Enhancing [[beta]]-carotene content in potato by RNAi-mediated silencing of the [[beta]]-carotene hydroxylase gene. Ame J Potato Res (2007).

  3. Jason Collens, Hugh Mason, Wayne Curtis. Agrobacterium-mediated viral vector-amplified transient gene expression in Nicotiana glutinosa plant tissue culture. Biotechnol Prog (2007).

  4. Book chapter: Santi, L,Mason, Hugh S (Author) . Vaccines Produced in Transgenic Plants. Encyclopedia of Biotechnology in Agriculture and Food. Taylor & Francis Group (2007).


2006

  1. A Becerra-Arteaga, Hugh Mason, M Shuler. Production, Secretion, and Stability of Human Secreted Alkaline Phosphatase in Tobacco NT1 Cell Suspension Cultures. Biotechnol. Prog (2006).

  2. K Mayo, B Gonazales, Hugh Mason. Genetic transformation of tobacco NT1 cells with Agrobacterium tumefaciens. Nature Protocols (2006).

  3. L Santi, A Giritch, C Roy, S Marillonnet, V Klimyuk, Y Gleba, R Webb, C Arntzen, Hugh Mason. Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system. Proc. Natl. Acad. Sci. USA (2006).

  4. L Santi, Z Huang, Hugh Mason. Virus-like particles production in green plants. Methods (2006).

  5. M Alvarez, H Pinyerd, J Crisantes, M Rigano, J Pinkhasov, A Walmsley, Hugh Mason, Guy Cardineau. Plant-made subunit vaccine against pneumonic and bubonic plague is orally immunogenic in mice. Vaccine (2006).

  6. S Saldaña, L Richter, C Arntzen, M Gómez-Lim, F Guadarrama, T de Jesus Olivera Flores, N Arias, S López, C Arias, R Ruiz, Hugh Mason, T Mor. Production of rotavirus-like particles in tomato (Lycopersicon esculentum L.) fruit by expression of capsid proteins VP2 and VP6 and immunological studies. Viral Immunol (2006).

  7. X Zhang, Hugh Mason. Bean yellow dwarf virus replicons for high-level transgene expression in transgenic plants and cell cultures. Biotechnol Bioeng (2006).

  8. X Zhang, N Buehner, A Hutson, M Estes, Hugh Mason. Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein. Plant Biotechnol. J (2006).

  9. Zhong Huang, L Santi, K LePore, J Kilbourne, C Arntzen, Hugh Mason. Rapid, high-level production of hepatitis B core antigen in plant leaf and its immunogenicity in mice. Vaccine (2006).

  10. Santi, L, Huang, Z, Mason, Hugh. Virus-like particles production in green plants. Methods (2006).

  11. Thanavala, Y, Huang, Z, Mason, Hugh. Plant-derived vaccines: a look back at the highlights and a view to the challenges on the road ahead(2006).

  12. Thanavala, Y, Huang, Z, Mason, Hugh. Plant-derived vaccines: a look back at the highlights and a view to the challenges on the road ahead.Expert Rev. Vaccines (2006).


2005

  1. C Arntzen, R Mahoney, Hugh Mason, D Kirk. Oral Vaccines Derived from Transgenic Plants. Vaccines: Preventing disease and protecting health(2005).

  2. C Mihalek, J Van Eck, S Webb, T Miller, M Fanton, D Kirk, G Cardineau, Hugh Mason, A Walmsley, A Artnzen. Development of plant cell produced vaccines for animal health applications. Proc. Ann. Meeting U.S. Animal Health Assoc (2005).

  3. J Bryan, B Maloney, Naokazu Takeda, Yuriko Suzaki, Ami Yasushi, Tian Li, Tatsuo Miyamura, Charles Arntzen, Hugh Mason. Challenges in creating a vaccine to prevent hepatitis E. Vaccine (2005).

  4. Y Thanavala, M Mahoney, S Pal, A Scott, L Richter, N Natarajan, P Goodwin, C Arntzen, Hugh Mason. Immunogenicity in humans of an edible vaccine for hepatitis B. Proc. Natl. Acad. Sci. USA (2005).

  5. Zhong Huang, G Elkin, B Maloney, N Beuhner, C Arntzen, Y Thanavala, Hugh Mason. Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses. Vaccine (2005).