Huansheng Cao

Huansheng Cao

Assistant Research Professor, Biodesign Center for Fundamental and Applied Microbiomics


Computational and Experimental Systems Biology

Basic Systems Biology Research

  • Microbiome studies using genomics, phylogenetics, transcriptomics, and metabolomics (under global change or other environments)
  • Elucidation of microbial metabolic network structure and associated regulatory systems
  • Multi-omics data mining and computational integration based on metabolic network flux and topology
  • Evolutionary and functional genomics based on metabolic network flux and topology
  • Characterization of bacterial genomic organization and associated regulatory systems
  • Robustness and evolvability of biological systems under environmental change and the systems determinants (genomics, transcriptomics, and metabolomics)

Applied Systems Biology Research

  • population genetics, conservation biology, and evolutionary ecology at the molecular, population, community, and ecosystem levels under global change
  • development and application of next-generation bioengineering pipeline based on large-scale metabolic network reconstruction and flux optimization
  • systems study of toxicity of biofuels and environmental stressors in terms of tradeoff between survival and growth on the balance of energy and mass
  • evolutionary ecology of toxic blooms under increasing water eutrophication and global climate change
  • pathogen control by development of antibiotics against key reactions as new targets