Pubmed logo      Google Scholar


  1. C.R. Simmons, T. MacCulloch, F. Zhang, Y. Liu, N. Stephanopoulos & H. Yan, A Self-Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High Resolution Structural Detail, Angew. Chem. Int. Ed. in press, (2020).

  2. S. Jiang, F. Zhang & H. Yan, Complex assemblies and crystals guided by DNA, Nat. Mater. 19, 694-700, (2020).

  3. J. Georges, X. Qi, X. Liu, Y. Zhou, E. C. Woolf, A. Valeri, Z. Al-Atrache, E. Belykh, B. Feuerstein, M. Preul, A. C. Scheck, M. Reiser, T. Anderson, J. Gopez, D. Appelt, S. Yocom, J. Eschbacher, H. Yan, P. Nakaji, A Fluorescent Aptamer Provides Rapid and Specific Ex Vivo Diagnosis of Central Nervous System Lymphoma from Rodent Xenograft Biopsies, J. Neurosurg. in press, (2020).

  4. J. Li', J. Dai', S. Jiang', M. Xie', T. Zhai, L. Guo, S. Cao, S. Xing, Z. Qu, Y. Zhao, F. Wang, Y. Yang, L. Liu, X. Zuo, L. Wang*, H. Yan*, C. Fan*, Encoding quantized fluorescence states with fractal DNA frameworks, Nat. Commun. 11, 2185, (2020).

  5. X. Qi, X. Liu, L. Matiski, R. Rodriguez Del Villar, T. Yip, F. Zhang, S. Sokalingam, S. Jiang, L. Liu, H. Yan, Y. Chang, RNA Origami Nanostructures for Potent and Safe Anti-Cancer Immunotherapy, ACS Nano 14, 4727-4740, (2020).

  6. F. Hong, D. Ma, K, Wu, L.A. Mina, R.C. Luiten, Y. Liu, H. Yan*, A.A. Green*, Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators, Cell 180, 1018-1032, (2020).

  7. G. Yao, J. Li, Q. Li, X. Chen, X. Liu, F. Wang, Z. Qu, Z. Ge, R.P. Narayanan, D. Williams, H. Pei, X. Zuo, L. Wang, H. Yan, B.L. Feringa*, C. Fan*, Programming nanoparticle valence bonds with single-stranded DNA encoders, Nature Materials 19, 781-788, (2020).


  1. C. Zhang*, Z. Wang, Y. Liu, J. Yang, X. Zhang, Y. Li, L. Pan, Y. Ke*, H. Yan*, Nicking-Assisted Reactant Recycle to Implement Entropy-Driven DNA Circuit, J. Am. Chem. Soc. 141, 17189-17197, (2019).

  2. Z. Zhao, C. Wang, H. Yan,* Y. Liu*, Soft Robotics Programmed with Double Crosslinking DNA Hydrogels, Advanced Functional Materials 1905911, (2019).

  3. X. Jing, F. Zhang, P. Pan, X. Dai, J. Li, L. Wang, H. Yan, C. Fan, Solidifying framework nucleic acids with silica, Nature Protocols 14, 2416-2436, (2019).

  4. X. Wang, A. Chandrasekaran, R. Arun, Z. Shen, Y. Ohayon, T. Wang, M. Kizer, R. Sha, C. Mao, H. Yan, X. Zhang, S. Liao, B. Ding, B. Chakraboty, N. Jonoska, D. Niu, H. Gu, J. Chao, X. Gao, Y. Li, T. Ciengshin, N. Seeman, Paranemic Crossover DNA: There and Back Again, Chemical Reviews 119, 6273-6289, (2019).

  5. Y. Zhou, X. Qi, Y. Liu, F. Zhang, H. Yan, DNA Nanoscaffold-Assisted Selection of Femtomolar Bivalent Aptamers for Human α-Thrombin with Potent Anticoagulant Activity, ChemBioChem 20, 2494-2503 (2019).

  6. S. Mandal', X. Zhou', S. Lin, H. Yan, N. Woodbury, Directed Energy Transfer through DNA-Templated J-aggregates, Bioconjugate Chemistry 30, 1870-1879, (2019).

  7. X. Zhou', S. Mandal', S. Jiang, S. Lin, J. Yang, Y. Liu, D. Whitten, N. Woodbury, H. Yan, Efficient Long-rnage, Directional Energy Transfer through DNA-Templated Dye Aggregates, J. Am. Chem. Soc. 141, 8473-8481, (2019).

  8. L. Xin, M. Lu, S. Both, M. Pfeifer, M. Urban, C. Zhou, H. Yan, T. Weiss, N. Liu, K. Lindfors, Watching a Single Fluorofphore Molecule Walk into a Plasmonic Hotspot, ACS Photonics 6, 985-993, (2019).

  9. Y. Xu, S. Jiang, C. Simmons, R. Narayanan, F. Zhang, A. Aziz, H. Yan, N. Stephanopoulos*, Tunable Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks, ACS Nano 13, 3545–3554, (2019).

  10. H. Jun', F. Zhang', T. Shepherd, S. Ratanalert, X. Qi, H. Yan, M. Bathe*, Autonomously designed free-form 2D DNA origami, Science Advances 5, eaav0655, (2019).

  11. Z. Ge, J. Fu, M. Liu, S. Jiang, A. Andreoni, X. Zuo, Y. Liu, H. Yan*, C. Fan*, Constructing Submonolayer DNA Origami Scaffold on Gold Electrode for Wiring of Redox Enzymatic Cascade Pathways, ACS Appl. Mater. Interfaces 11, 13881-13887 (2019).

  12. Z. Ge, Z. Su, C. R. Simmons, J. Li, S. Jiang, W. Li, Y. Yang, Y. Liu*, W. Chiu, C. Fan*, H. Yan*, Redox Engineering of Cytochrome c using DNA Nanostructure-Based Charged Encapsulation and Spatial Control, ACS Appl. Mater. Interfaces 11, 13874-13880 (2019).


  1. F. Hong, S. Jiang, X. Lan, R. Narayanan, P. Sulc, F. Zhang*, Y. Liu*, H. Yan*, Layered-Crossover Tiles with Precisely Tunable Angles for 2D and 3D DNA Crystal Engineering, J. Am. Chem. Soc. 140, 14670–14676, (2018).

  2. X. Qi', F. Zhang'*, Z. Su', S. Jiang, D. Han, B. Ding, Y. Liu, W. Chiu, P. Yin, H. Yan*, Programing Molecular Topologies from Single-stranded Nucleic Acids, Nature Commun. 9, 4579, (2018).

  3. D. Jiang', Z. Ge', H. Im, C. England, D. Ni, J. Hu, L. Zhang, C. Kutyreff, Y. Yan, Y. Liu, S. Cho, J. Engle, J. Shi, P. Huang, C. Fan*, H. Yan*, W. Cai*, DNA-origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury, Nature Biomed. Eng. 2, 865–877, (2018).

  4. X. Lan*, T. Liu, Z. Wang, A. Govorov*, H. Yan, Y. Liu*, DNA-Guided Plasmonic Helix with Switchable Chirality, J. Am. Chem. Soc. 140, 11763–11770, (2018).

  5. F. Zhang', C. Simmons', J. Gates, Y. Liu, H. Yan*, Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry, Angew Chem Int Ed. 57, 12504–12507, (2018).

  6. X. Liu', F. Zhang', X. Jing', M. Pan, P. Liu, W. Li, B. Zhu, J. Li, H. Chen, L. Wang, J. Lin, Y. Liu, D. Zhao, H. Yan* & C. Fan*, Complex silica composite nanomaterials templated with DNA origami, Nature 559, 593-598, (2018).

  7. J. Li, A. Johnson-Buck, Y. Yang, W. Shih, H. Yan, N. Walter*, Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat, Nature Nanotechnol. 13, 723-729, (2018).

  8. S. Li, Q. Jiang, S. Liu, Y. Zhang, Y. Tian, C. Song, J. Wang, Y. Zou, G. J. Anderson, J. Han, Y. Chang, Y. Liu, C. Zhang, L. Chen, G. Zhou, G. Nie*, H. Yan*, B. Ding*, Y. Zhao*, A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo, Nature Biotechnology 36, 258–264, (2018).

  9. E. Boulais, N. Sawaya, R. Veneziano, A. Andreoni, J. Banal, T. Kondo, S. Mandal, S. Lin, G. Schlau-Cohen, N. Woodbury, H. Yan*, A. Aspuru-Guzik*, M. Bathe*, Programmed coherent coupling in a synthetic DNA-based excitonic circuit, Nature Materals 17, 159–166, (2018).


  1. Y. R. Yang, J. Fu, S. Wootten, X. Qi, M. Liu, H. Yan, Y. Liu* 2D Enzyme Cascade Network with Efficient Substrate Channeling by Swinging Arms, ChemBioChem. DOI: 10.1002/cbic.201700613 (2017).

  2. D. Han', X. Qi', C. Myhrvold, B. Wang, M. Dai, S. Jiang, M. Bates, Y. Liu, B. An*, F. Zhang*, H. Yan* and P. Yin*, Single-stranded DNA and RNA Origami, Science 358, eaao2648, (2017).

  3. F. Zhang, H. Yan*, DNA self-assembly scaled up, Nature 552, 34–35, (2017).

  4. A. Carey, H. Zhang, M. Liu, D. Sharaf, N. Akram, H. Yan, S. Lin, N. Woodbury*, D. Seo*, Enhancing Photocurrent Generation in Photosynthetic Reaction Center-based Photoelectrochemical Cells with Biomimetic DNA Antenna, ChemSusChem 10, 4457-4460, (2017).

  5. S. Jiang, F. Hong, H. Hu, H. Yan*, Y. Liu*, Understanding the Elementary Steps in DNA Tile-Based Self-Assembly, ACS Nano. 11, 9370–9381, (2017).

  6. J. Li, A. A. Green, H. Yan, C. Fan, Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation, Nature Chem. 9, 1056–1067, (2017).

  7. C. Simmons, F. Zhang, T. MacCulloch, N. Fahmi, N. Stephanopoulos, Y. Liu, N. Seeman, H. Yan, Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals. J. Am. Chem. Soc. 139, 11254–11260, (2017).

  8. D. Mieritz, X. Li, A. Volosin, M. Liu, H. Yan, N. Walter, D. Seo, Tracking Single DNA Nanodevices in Herarchically Meso-Macroporous Antimony-Doped Tin Oxide Demonstrates Finite Confinement, Langmuir 33, 6410–6418, (2017).

  9. F. Hong, F. Zhang, Y. Liu*, H. Yan*, DNA Origami:Scaffolds for Creating Higher Order Structures, Chem. Rev. 117, 12584–12640, (2017).

  10. H. Zhang, A. Carey, K. Jeon, M. Liu, T. Murell, J. Locsin, S. Lin, H. Yan, N. Woodbury, D. Seo, A Highly Stable and Scalable Photosynthetic Reaction Center-Graphene Hybrid Electrode System for Biomimetic Solar Energy Transduction, J. Mater. Chem. A. 5, 6038–6041, (2017).

  11. F. Zhang, F. Hong, H. Yan*, DNA Origami Tiles: Nanoscale Mazes, Nature Nanotechnol.12, 189–190, (2017).

  12. Y. Dong, Y. Yang, Y. Zhang, D. Wang, X. Wei, S. Banerjee, Y. Liu, Z. Yang, H. Yan*, D. Liu*, Cuboid Vesicles Formed by Frame-guided Assembly on DNA Origami Scaffolds, Angew Chem Int Ed. 156, 1586–1589, (2017).

  13. A. Andreoni, S. Lin, H. Liu, R. E. Blankenship, H. Yan, N. Woodbury, Orange Carotenoid Protein as a Control Element in an Antenna System based on a DNA Nanostructure, Nano Letters 17, 1174–1180, (2017).


  1. F. Hong, S. Jiang, T. Wang, Y. Liu*, H. Yan*, 3D Framework DNA origami with Layered Crossovers, Angew Chem Int Ed. 128, 13024–13027, (2016).

  2. A. Carey, H. Zhang, D. Mieritz, A. Volosin, A. Gardiner, R. Cogdell, H. Yan, D. Seo, S. lin, N. Woodbury*, Photocurrent generation by photosynthetic purple bacterial reaction centers interfaced with a porous antimony-doped tin oxide (ATO) electrode, ACS Appl. Matter. Interfaces 8, 25104–25110, (2016).

  3. J. Fu*, Y. Yang, S. Dhakal, Z. Zhao, M. Liu, T. Zhang, N. Walter, H. Yan, Assembly of Multi-Enzyme Complexes on DNA Nanostructures, Nature Protocols 11, 2243–2273, (2016).

  4. C. Simmons, F. Zhang, J. Birktoft, X. Qi, D. Han, Y. Liu, R. Sha, H. Abdallah, C. Hernandez, Y. Ohayon, N. Seeman*, H. Yan*, Construction and Structure Determination of a Three-dimensional DNA Crystal, J. Am. Chem. Soc. 138, 10047–10054, (2016).

  5. R. Veneziano, S. Ratanalert, K. Zhang, F. Zhang, H. Yan, W. Chiu, M. Bathe*, Designer nanoscale DNA assemblies programmed from the top down, Science 10.1126/science.aaf4388 (2016).

  6. F. Zhang*, S. Jiang, W. Li, A. Hunt, Y. Liu*, H. Yan*, Self-assembly of Complex DNA Tessellations using low symmetry multi-arm DNA tiles, Angew Chem Int Ed. 55, 8860–8863, (2016).

  7. G. Ke, M. Liu, S. Jiang, X. Qi, Y. R. Yang, S. Wootten, F. Zhang, Z. Zhu, Y. Liu*, C. J. Yang*, H. Yan*, Directional Regulation of Enzyme Pathways via the Control of Substrate Channeling on a DNA Origami Scaffold, Angew Chem Int Ed. 55, 7483–7486, (2016).

  8. M. Liu, J. Fu, X. Qi, S. Wootten, N. Woodbury, Y. Liu*, H. Yan*, A three-enzyme pathway with an optimized geometric arrangement to facilitate substrate transfer, ChemBioChem 17, 1097–1101, (2016).

  9. W. Li, F. Zhang, H. Yan*, Y. Liu*, DNA Based Arithmetic Function: Half Adder Based on DNA Strand Displacement, Nanoscale 8, 3775–3784, (2016).

  10. Z. Zhao, J. Fu, S. Dhakal, A. Johnson-Buck, M. Liu, T. Zhang, N. Woodbury, Y. Liu, N. Walter, H. Yan*, Nano-caged Enzymes with Enhanced Catalytic Activity and Increased Stability against Protease Digestion, Nature Commun. 7, 10619 (2016).

  11. S. Dhakal, M. R. Adendorff, M. Liu, H. Yan*, M. Bathe*, N. G. Walter*, Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis, Nanoscale 8, 3125–3137, (2016).

  12. C. Zhang, J. Yang, S. Jiang, Y. Liu*, H. Yan*, DNAzyme-based Logic Gate-mediated DNA Self-assembly, Nano Letters 16, 736–741, (2016).


  1. Zhang, F.; Jiang, S.; Wu, S.; Li, Y.; Mao, C.; Liu, Y.; Yan, H., Complex wireframe DNA origami nanostructures with multi-arm junction vertices. Nat Nanotechnol 2015, 10 (9), 779-84;

  2. Yang, Y. R.; Liu, Y.; Yan, H., DNA Nanostructures as Programmable Biomolecular Scaffolds. Bioconjug Chem 2015, 26 (8), 1381-95;

  3. Georges, J. F.; Liu, X.; Eschbacher, J.; Nichols, J.; Mooney, M. A.; Joy, A.; Spetzler, R. F.; Feuerstein, B. G.; Preul, M. C.; Anderson, T.; Yan, H.; Nakaji, P., Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model. PLoS One 2015, 10 (4), e0123607;


  1. Zhang, F.; Nangreave, J.; Liu, Y.; Yan, H., Structural DNA nanotechnology: state of the art and future perspective. J Am Chem Soc 2014, 136 (32), 11198-211;

  2. Wang, D.; Capehart, S. L.; Pal, S.; Liu, M.; Zhang, L.; Schuck, P. J.; Liu, Y.; Yan, H.; Francis, M. B.; De Yoreo, J. J., Hierarchical assembly of plasmonic nanostructures using virus capsid scaffolds on DNA origami templates. ACS Nano 2014, 8 (8), 7896-904;

  3. Seeman, N. C.; Mao, C.; Yan, H., Guest editorial: nucleic acid nanotechnology. Acc Chem Res 2014, 47 (6), 1643-4;

  4. Samanta, A.; Zhou, Y.; Zou, S.; Yan, H.; Liu, Y., Fluorescence quenching of quantum dots by gold nanoparticles: a potential long range spectroscopic ruler. Nano Lett 2014, 14 (9), 5052-7;

  5. Pan, K.; Kim, D. N.; Zhang, F.; Adendorff, M. R.; Yan, H.; Bathe, M., Lattice-free prediction of three-dimensional structure of programmed DNA assemblies. Nat Commun 2014, 5, 5578;

  6. Liang, L.; Li, J.; Li, Q.; Huang, Q.; Shi, J.; Yan, H.; Fan, C., Single-particle tracking and modulation of cell entry pathways of a tetrahedral DNA nanostructure in live cells. Angewandte Chemie 2014, 53 (30), 7745-50;

  7. Li, W.; Yang, Y.; Jiang, S.; Yan, H.; Liu, Y., Controlled nucleation and growth of DNA tile arrays within prescribed DNA origami frames and their dynamics. J Am Chem Soc 2014, 136 (10), 3724-7;

  8. Johnson-Buck, A.; Jiang, S.; Yan, H.; Walter, N. G., DNA-cholesterol barges as programmable membrane-exploring agents. ACS Nano 2014, 8 (6), 5641-9;

  9. Jiang, S.; Yan, H.; Liu, Y., Kinetics of DNA tile dimerization. ACS Nano 2014, 8 (6), 5826-32;

  10. Fu, J.; Yang, Y. R.; Johnson-Buck, A.; Liu, M.; Liu, Y.; Walter, N. G.; Woodbury, N. W.; Yan, H., Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm. Nat Nanotechnol 2014, 9 (7), 531-6;

  11. Flory, J. D.; Simmons, C. R.; Lin, S.; Johnson, T.; Andreoni, A.; Zook, J.; Ghirlanda, G.; Liu, Y.; Yan, H.; Fromme, P., Low temperature assembly of functional 3D DNA-PNA-protein complexes. J Am Chem Soc 2014, 136 (23), 8283-95;

  12. Edwards, A.; Yan, H., DNA Origami. In Nucleic Acid Nanotechnology, Kjems, J.; Ferapontova, E.; Gothelf, K. V., Eds. 2014; Vol. 29, pp 93-133;

  13. Dutta, P. K.; Lin, S.; Loskutov, A.; Levenberg, S.; Jun, D.; Saer, R.; Beatty, J. T.; Liu, Y.; Yan, H.; Woodbury, N. W., Reengineering the optical absorption cross-section of photosynthetic reaction centers. J Am Chem Soc 2014, 136 (12), 4599-604;

  14. Dutta, P. K.; Levenberg, S.; Loskutov, A.; Jun, D.; Saer, R.; Beatty, J. T.; Lin, S.; Liu, Y.; Woodbury, N. W.; Yan, H., A DNA-directed light-harvesting/reaction center system. J Am Chem Soc 2014, 136 (47), 16618-25.


  1. A. Johnson-Buck, J. Nangreave, D. Kim, M. Bathe, H. Yan, N. Walter. Super-Resolution Fingerprinting Detects Chemical Reactions and Idiosyncrasies of Single DNA Pegboards. Nano Letters.

  2. A. Johnson-Buck, J. Nangreave, S. Jiang, H. Yan, N. Walter. Multifactorial Modulation of Binding and Dissociation Kinetics on Two-Dimensional DNA Nanostructures. Nano Letters.

  3. D. Han, S. Jiang, A. Samanta, Y. Liu, H.Yan. Unidirectional Scaffold-Strand Arrangement in DNA Origami. Angew Chem Int Ed.

  4. D. Han, S. Pal, Y. Yang, S. Jiang, J. Nangreave, Y. Liu, H. Yan. DNA Gridiron Nanostructures Based on Four-Arm Junctions. Science.

  5. F. Zhang, Y. Liu, H. Yan. Complex Archimedean Tiling Self-assembled from DNA Nanostructures. J. Am. Chem. Soc.

  6. J. Flory, S. Shinde, S. Lin, Y. Liu, H. Yan, G. Ghirlanda, P. Fromme. PNA-peptide Assembly in a 3D DNA Nanocage at Room Temperature. J. Am. Chem. Soc.

  7. M. Liu, J. Fu, C. Hejesen, Y. Yang, N. W. Woodbury, K. Gothelf, Y. Liu, H. Yan. A DNA Tweezer-Actuated Enzyme Nanoreactor. Nature Communications.

  8. O. Schulz, Z. Zhao, A. Ward, M. Koenig, F. Koberling, Y. Liu, J. Enderlein, H. Yan and R. Ros. Tip Induced Fluorescence Quenching for Nanometer Optical and Topographical Resolution. Optical Nanoscopy.

  9. Q. Mei, R. H. Johnson, X. Wei, F. Su, Y. Liu, L. Kelbauskas, S. Lindsay, D. R. Meldrum, and H. Yan. On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate. Nano Research.

  10. S. Pal, P. Dutta, H. Wang, Z. Deng, S. Zou, H. Yan, Y. Liu. Quantum Efficiency Modification of Organic Fluorophores Using Gold Nanoparticles on DNA Origami Scaffolds. J. Phys. Chem. C.

  11. W. Li, Y. Yang, H. Yan, Y. Liu. 3-Input Majority Logic Gate and Multiple Input Logic Circuit Based on DNA Strand Displacement. Nano Letters.

  12. X. Liu, Y. Liu, H. Yan. Functionalized DNA Nanostructures for Nanomedicine. Israel Journal of Chemistry.

  13. X. Wei, J. Nangreave, S. Jiang, H. Yan, Y. Liu. Mapping the Thermal Behavior of DNA Origami Nanostructures. J. Am. Chem. Soc.

  14. Y. Yang, Z. Zhao, F. Zhang, J. Nangreave, Y. Liu, H. Yan. Self-assembly of DNA Rings from Scaffold Free DNA Tiles. Nano Letters.

  15. Z. Deng, S. Pal, A. Samanta, H. Yan, Y. Liu. DNA Functionalization of Colloidal II-VI Semiconductor Nanowires. Chemical Sciences.

  16. Z. Zhao, Y. Liu, H. Yan. DNA Origami Templated Self-assembly of Discrete Length Single Wall Carbon Nanotubes. Org. Biomol. Chem.


  1. A. V. Pinheiro, J. Nangreave, S, Jiang, H. Yan, Y. Liu. Steric Crowding and the Kinetics of DNA Hybridization within a DNA Nanostructure System. ACS Nano.

  2. F. Zhang, J. Nangreave, Y. Liu, H. Yan. Reconfigurable DNA Origami to Generate Quasi-Fractal Patterns. Nano Letters.

  3. J. Fu, H. Yan. Controlled Drug Release by a Nanorobot. Nature Biotechnology.

  4. J. Fu, M. Liu, Y. Liu, H. Yan. Spatially-Interactive Biomolecular Networks Organized by Nucleic Acid Nanostructures. Acc. Chem. Res.

  5. J. Fu, M. Liu, Y. Liu, N. W. Woodbury, H. Yan. Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures. J. Am. Chem. Soc.

  6. N. Lu, H. Pei, Z. Ge, C. R. Simmons, H. Yan, C. Fan. Charge Transport within A Three-Dimensional DNA nanostructure Framework. J. Am. Chem. Soc (2012).

  7. Q. Jiang, C. Song, J. Nangreave, X. Liu, L. Lin, D. Qiu, Z. Wang, G. Zou, X. Liang, H. Yan, B. Ding. DNA Origami as a Carrier for Circumvention of Drug Resistance. J. Am. Chem. Soc.

  8. X. Liu, Y. Xu, T. Yu, C. Craig, Y. Liu, H. Yan, Y. Chang. A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines,. Nano Letters.

  9. Y. Yang, D. Han, J. Nangreave, , Y. Liu, H. Yan,. DNA Origami with Double-Stranded DNA As a Unified Scaffold. ACS Nano.

  10. Z. Deng, A. Sanmanta, J. Nangreave, H. Yan, Y. Liu. Robust DNA Functionalized Core/Shell Quantum Dots with Fluorescent Emission Spanning from UV-Vis to Near IR and Compatible with DNA Directed Self-Assembly. J. Am. Chem. Soc.

  11. Z. Li, L. Wang, H. Yan, Y. Liu. Effect of DNA Hairpin Loops on the Twist of Planar DNA Origami Tiles. Langmuir.

  12. J. Fu, H. Yan. Controlled Drug Release by a Nanorobot. Nature Biotechnology.


  1. A. Pinheiro, D. Han, W. M. Shih,*, H. Yan*. Challenges and Opportunities for Structural DNA Nanotechnology. Nature Nanotechnology.

  2. D. Han*, S. Pal, J. Nangreave, Z. Deng, Y. Liu*, H. Yan*. DNA Origami with Complex Curvatures in Three-dimensional Space. Science.

  3. J. Nangreave, H. Yan, Y. Liu*. DNA Nanostructures as Models for Evaluating the Role of Enthalpy and Entropy in Polyvalent Binding. J. Am. Chem. Soc.

  4. P. Dutta, R. Varghese, S. Lin, H. Yan, Y. Liu*. DNA Directed Artificial Light Harvesting Systems. J. Am. Chem. Soc.

  5. Q. Mei, X. Wei, F. Su, Y. Liu, C. Youngbull, R. Johnson, S. Lindsay, H. Yan*, D. Meldrum*. Stability of DNA Origami Nanoarrays in Cell Lysate. Nano Letters.

  6. S. Pal, Z. Deng, Y. Liu*, H. Yan*. DNA Origami Directed Self-assembly of Anisotropic Plasmonic Nanostructures.. J. Am. Chem. Soc.

  7. S.Pal, R. Varghese, H. Yan*, Y. Liu*. Site Specific Synthesis and in-situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds Using Tollens Reaction. Angew Chem Int Ed.

  8. T. Torring, N. V. Voigt, J. Nangreave, H. Yan*, K. Gothelf*. DNA Origami: A quantum leap for self-assembly of complex structures. Chem. Soc. Rev.

  9. X. Liu, H. Yan, Y. Liu*, Y. Chang*. Targeted Cell-Cell Interactions by DNA Nanoscaffold-Templated Multivalent Bi-specific Aptamers. Small.

  10. Z. Deng, L. Tong, S. Lin, M. Flores, J. Cheng, H. Yan, Y. Liu*. High Quality Manganese-Doped Zinc Sulfide Quantum Rods with Tunable Dual-Color and Multi-Photon Emissions. J. Am. Chem. Soc.

  11. Z. Zhao, Y. Liu*, H. Yan*. Encapsulation of Gold Nanoparticles in a DNA Origami Cage. Angew Chem Int Ed..