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  1. H. Jun†, F. Zhang†, S. Ratanalert, T. Shepherd, X. Qi, H. Yan, M. Bathe. Autonomously Designed Free-form DNA Origami. Science Advances Accept (2018). Co-first Author
  2. X. Qi†, F. Zhang†*, Z. Su†, S. Jiang, D. Han, Y. Liu, W. Chiu, P. Yin, H. Yan*. Programming Molecular Topologies from Single-stranded Nucleic Acids. Nature Communications In press (2018).
    * Corresponding author. Co-first Author
  3. F. Hong, S. Jiang, X. Lan, R. N. Pradeep, P. Sulc, F. Zhang*, Y. Liu*, H. Yan*. Layered-Crossover Tiles with Precisely Tunable Angles for 2D and 3D DNA crystal Engineering. Journal of the American Chemical Society In press (2018). *Corresponding author
  4. X. Liu†, F. Zhang†, X. Jing†, M. Pan, P. Liu, W. Li, B. Zhu, J. Li, H. Chen, L. Wang, J. Lin, Y. Liu, D. Zhao, H. Yan, C. Fan. Complex Silica Composite Nanomaterials Template with DNA Origami. Nature 559, 593 (2018). • Media coverage:, Nanowerk, Science Daily.
  5. F. Zhang†, C. Simmons†, J. Gates, Y. Liu, H. Yan. Self-assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry. Angewandte Chemie International Edition 130, 12684 (2018).


  1. C. Simmons, F. Zhang, T. MacCulloch, N. E. Fahmi, N. Stephanopoulos, Y. Liu, N. Seeman, H. Yan. Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals. Journal of the American Chemical Society 139, 11254 (2017).
  2. F. Zhang, H. Yan. DNA Self-assembly Scaled Up. Nature 552, 34 (2017).
  3. F. Zhang, F. Hong, H. Yan. DNA origami tiles: Nanoscale mazes. Nature Nanotechnology 12, 189 (2017).
  4. F Hong, F. Zhang, Y. Liu, H. Yan. DNA Origami: Scaffolds for Creating Higher Order Structures. Chemical Reviews 117, 12584 (2017).
  5. D. Han, X. Qi, C. Myhrvold, B. Wang, M. Dai, S. Jiang, M. Bates, Y. Liu, B. An*, F. Zhang*, H. Yan*, P. Yin*. Single-stranded DNA and RNA Origami. Science 358, eaao2648 (2017). *Corresponding author


  1. C. Simmons, F. Zhang, J. Birktoft, D. Han, Y. Liu, R. Sha, H. Abdallah, C. Hernandez, Y. Ohayon, N. C. Seeman, H. Yan. Construction and Structure Determination of a Self-assembling DNA Crystal. Journal of the American Chemical Society 138, 10047 (2016).

  2. F. Zhang, S. Jiang, W. Li, A. Hunt, Y. Liu, H. Yan, Self-assembly of Complex DNA tessellations, Angew Chem Int Ed, in revision (2016)

  3. R. Veneziano, S. Ratanalert, K. Zhang, F. Zhang, H. Yan, W. Chiu, M. Bathe, Top-down Design of DNA Polyhedral Meshes, Science, in revision (2016).

  4. G. Ke, M. Liu, S. Jiang, X. Qi, Y. Yang, S. Wootten, F. Zhang, Z. Zhu, Y. Liu, C. Yang, H. Yan. Directional Regulation of Enzyme Pathways via the Control of Substrated Channeling on a DNA Origami Scaffold, Angew Chem Int Ed, in press (2016)

  5. W. Li, F. Zhang, Y. Liu, H. Yan. Half Adder Based on DNA Strand Displacement. Nanoscale, 8, 3775-3784 (2016).


  1. F. Zhang, S. Jiang, S. Wu, Y. Li, C. Mao, Y. Liu, H. Yan, Complex Wireframe DNA Origami Nanostructures with Multi-arm Junction Vertices. Nature Nanotechnology, 10,779-784 (2015).

  2. X. Ye, F. Zhang, Y. Ma, L. Qi, Brittle star‐Inspired Microlens Arrays Made of Calcite Single Crystals. Small, 11, 1677-1682 (2015).


  1. F. Zhang, J. Nangreave, Y. Liu, H. Yan, Structural DNA Nanotechnology: State of the Art and Future Perspective. J. Am. Chem. Soc., 136, 11198–11211 (2014).

  2. K. Pan, D. N. Kim, F. Zhang, M. Adendorff, H. Yan, M. Bathe, Lattice-free Prediction of Three-dimensional Structure of Programmed DNA Assemblies. Nature Communications, 5, 5078, (2014).


  1. F. Zhang, Y. Liu, H. Yan, Complex Archimedean Tiling Self-assembled from DNA Nanostructures. J. Am. Chem. Soc., 135, 7458–7461 (2013).

  2. Y. Yang, Z. Zhao, F. Zhang, J. Nangreave, Y. Liu, H. Yan, Self-assembly of DNA Rings from Scaffold Free DNA Tiles. Nano letters, 13, 1862–1866 (2013).


F. Zhang, J. Nangreave, Y. Liu, H. Yan, Reconfigurable DNA Origami to Generate Quasi-Fractal Patterns. Nano Letters, 12, 3290–3295 (2012).