Assistant Professor, Biodesign Center for Fundamental and Applied Microbiomics
Efrem Lim is a virologist who uses the tools of virus discovery to study host-virus interactions in human health and disease. The Lim lab studies interactions and evolution of the human virome in development and immunity.
The Lim lab integrates molecular virology and bioinformatic approaches to understand 1) how the virome shapes the trajectory of infant development, 2) how mother-infant relationships impact the virome and microbiome in HIV disease settings, 3) how metagenomic changes induced by immunosuppression affect transplant outcome, and 4) how viruses temper the homeostasis of the urinary tract in urinary disease.
Their research is being used in precision medicine that personalizes the prevention and treatment of diseases to individuals.