News & Events

Evolutionary trade-offs color cancer prognoses

December 1, 2015

In formulating his theory of evolution, Charles Darwin recognized species variation as the raw material from which Nature selects its winners and losers. Chance mutation and natural selection, cornerstones in the evolution of all life, can also determine the fate of cells in a cancerous tumor, allowing some to slip through the body’s safeguards and live another day. In a new study, evolutionary biologist Carlo Maley—a researcher at Arizona State University’s Biodesign...

Elephants provide big clue in fight against cancer

October 9, 2015

Carlo Maley spends his time pondering pachyderms — and cactuses and whales, and a wide array of non-human species — all in pursuit of the answer to this question: Why do some life forms get cancer while others do not? The question of why big animals don't get more cancer than small ones is a long-standing mystery, one that scientists call “Peto’s Paradox.” Logic would seem to say that the more cells you have, the more likely there’s a cell that will mutate and produce a tumor....

Molecular and Cellular Biology Colloquium

September 30, 2015

"The Evolution and Ecology of Neoplastic Cells," Carlo Maley, Ph.D., Associate Professor, Biodesign’s Cancer and Evolution Lab More information 

Learning from extinction: new insights on controlling cancer

February 17, 2015

The earth is in the throes of a sixth mass extinction of species. Unlike those that preceded it, the current die-off is largely driven by human activity—the destruction of diverse habitats; the pollution of air, earth, and water; the disruption of the planet’s climate. According to a new study however, humankind’s ability to understand (and often drive) species extinction may be harnessed in the battle against cancer. Carlo Maley, Ph.D., a researcher at the Biodesign Institute's...