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Select publications

  1. Wasielewski H, Alcock J, Aktipis AResource conflict and cooperation between human host and gut microbiota: implications for nutrition and health. Ann N Y Acad Sci. 2016 Jun 6. doi: 10.1111/nyas.13118. [Epub ahead of print]

  2. Aktipis, C. A., Boddy, A., Jansen, G., Hochberg, M., Maley, C., Hibner, U., Wilkinson, G. (2015). Cancer across life: Cooperation and cheating in multicellularity. Philosophical Transactions of the Royal Society B. Published online June 8 DOI: 10.1098/rstb.2014.0219

  3. Boddy, A., Kokko, H., Breden, F., Wilkinson, G. Aktipis, C. A.,  (2015). Cancer susceptibility and reproductive tradeoffs: A model of the evolution of cancer defenses. Philosophical Transactions of the Royal Society B. Published online June 8 DOI: 10.1098/rstb.2014.0220

  4. Brown, J., Aktipis, C.A., Inclusive fitness effects can select for cancer suppression into old age. Philosophical Transactions of the Royal Society B. Published online June 8 DOI: 10.1098/rstb.2015.0160

  5. Aktipis, C.A., Ellis, B.J., Nishimura, K., Hiatt, R.A., (2014). Modern reproductive patterns associated with estrogen receptor positive but not negative breast cancer susceptibility. Evolution, Medicine, and Public Health (2014): eou028.

  6. Hidaka, B. H., Asghar, A., Aktipis C.A., Nesse, R.M., Wolpaw, T.M., Skursky, N.K., Bennett, K.J., Beyrouty, M.W., Schwartz, M.D. (2015). The status of evolutionary medicine education in North American medical schools. BMC medical education 15(1): 38.

  7. Jansen, G., Gatenby, B., Aktipis, C.A. (2015). Control vs. eradication: Adopting strategies from infectious disease treatment to cancer. Proceedings of the National Academy of Sciences of the United States of America 112.4 937.


  1. Hao, Y., Cronk L., Armbruster, D., Aktipis, C.A. (2014). Need-based transfers on a network: A model of risk-pooling in ecologically volatile Environments

  2. Aktipis, C.A., Ellis, B.J., Nishimura, K., Hiatt, R.A., (2014). Modern reproductive patterns associated with estrogen receptor positive but not negative breast cancer susceptibility. Evolution, Medicine, and Public Health (2014): eou028.

  3. Jansen, G., and Aktipis, C.A. (2014). Resistance Is Mobile: The Accelerating Evolution of Mobile Genetic Elements Encoding Resistance. Journal of Evolutionary Medicine. Vol. 2, Article ID 235873, doi:10.4303/jem/235873

  4. Alcock, J., Maley, C.C., Aktipis, C.A. (2014). Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms.  Bioessays. Online publication 8/7/14

  5. Bryant, G, Aktipis C. A. (2014).  The animal nature of spontaneous human laughter.  Evolution and Human Behavior.  Online publication 3/31/2014


  1. Aktipis, C. A., Boddy, A., Brown, J., Gatenby, R, Maley C. C. (2013). Life history tradeoffs in cancer evolution. Nature Reviews Cancer, 13, 883-892.

  2. Aktipis, C.A., Nesse, R. (2013). Evolutionary foundations for cancer biology. Evolutionary Applications. 6(1) 144-159.

  3. Sprouffske, K, Aktipis, C. A., Radisch, J.P., Carroll, M, Nedulcu, A. M., Maley, C. C. (2013). An evolutionary explanation for the presence of cancer non-stem cells in neoplasms. Evolutionary Applications. 6(1) 92-101.


  1. Aktipis, C.A., Maley, C.C., Pepper, J. W. (2012). Dispersal evolution in neoplasms: The role of disregulated metabolism in the evolution of cell motility. Cancer Prevention Research. 5(2) 266-275


  1. Aktipis, C. A., Kwan, V.S.Y., Johnson, K. A., Neuberg, S.L., Maley, C.C. (2011) Overlooking evolution: A systematic analysis of cancer relapse and therapeutic resistance research. PLoS ONE 6(11): e26100. doi:10.1371/journal.pone.0026100

  2. Aktipis, C.A. (2011). Is cooperation viable in mobile organisms? Simple Walk Away strategy favors the evolution of cooperation in groups. Evolution and Human Behavior 32(4) 263-276.

  3. Aktipis, C. A., Cronk, L., De Aguilar, R. (2011). Risk-pooling and herd survival: An agent-based model of a Maasai gift-giving system. Human Ecology 39(2) 131-140.

  4. Aktipis, C.A., Fernandez-Duque, E. (2011). Parental investment without kin recognition: Simple rules for parent-offspring behavior. Behavioral Ecology and Sociobiology 65(5) 1079-1091.


  1. Aktipis, C.A., Thompson-Schill, S. (2010) Positive assortment for peer review. Adaptive Behavior, 18(5) 448-450.

  2. Phillips-Silver, J., Aktipis, C.A., Bryant, G. 2010. The ecology of entrainment: Foundations of coordinated rhythmic movement. Music Perception 28 (1) 3-14. NIHMSID # 289838

  3. Bendick, R., Dahlin, K.M., Smoliak, S., Kumler, L., Jones, S., Aktipis, C.A., Fugate, E., Hertog, R., Moberg, C., Scott, D.  2010.  Choosing carbon mitigation strategies using ethical deliberation. Weather, Climate and Society, 2(2), 140-147.


Kurzban, R.; Aktipis, C. A. 2007. Modularity and the social mind: Are Psychologists too self-ish?  Personality and Social Psychology Review, 11(2), 131-149.


Aktipis, C.A. 2006. Recognition memory and the evolution of cooperation: How simple strategies succeed in an agent-based world.  Adaptive Behavior, 14, 239-247.


  1. Aktipis, C.A. 2004. Know when to walk away: Contingent movement and the evolution of cooperation.  Journal of Theoretical Biology. 231(2), 249-260.

  2. Aktipis, C. A.; Kurzban, R.O. 2004.  Is Homo economicus extinct? Vernon Smith, Daniel Kahneman and the Evolutionary Perspective. Evolutionary Psychology and Economic Theory, Advances in Austrian Economics, 7, 135-153

  3. Wakeland, W.W.; Gallaher, E.J; Macovsky, L.M.; Aktipis, C. A. 2004.  A comparison of system dynamics and agent based simulation applied to the study of cellular receptor dynamics. 37th Annual Conference of the Hawaii International Complex System Society, January 2004.


  1. Aktipis, C. A. 2000.  The effect of behavioral assortment on selection dynamics: Externalities, information processing and subjective commitment.  Eilis Boudreau and Carlo Maley, eds., Proceedings of the Artificial Life VII Workshops, 90-93.

  2. Aktipis, C. A. 2000.  An evolutionary perspective on consciousness: The role of emotion, theory of mind and self-deception.  The Harvard Brain: Journal of Mind, Brain and Behavior, 7, 29-34.

Book Chapters and Other Contributions

  1. Greaves, M., Aktipis C. A. (in press).  Cancer in the modern world: Does mismatch with our ancestral environment enhance cancer risk? Frontiers in Cancer Research.

  2. Schiffman, J. D., White, R. M., Graham, T. A., Huang, Q, Aktipis, C. A. (in press)

The Darwinian dynamics of motility and metastasis. Frontiers in Cancer Research.

  1. Aktipis, C.A., Maley, C.C. (2011) The self-ish cell: Cancer’s emerging evolutionary paradigm. Evolution and Medicine Review (August 9).

  2. Aktipis, C. A., Maley, C. C., & Neuberg. S. L. (2010). Psychological barriers to evolutionary thinking in medicine. Evolution and Medicine Review (Feb 24).

  3. Aktipis, C. A. 2010. Book review ofWhy we cooperate’ by M. Tomasello. Journal of Artificial Societies and Social Simulation 13(3)

  4. Aktipis, C.A. 2008. When to Walk Away and when to stay: Cooperation evolves when agents can leave unproductive partners and groups.  Dissertation.

  5. Kurzban, R.; Aktipis, C. A. 2007b. On detecting the footprints of multilevel selection. Gangestad, S. W. & J. A. Simpson (Eds.) Evolution of Mind: Fundamental Questions and Controversies. New York: Guilford, 226-232.

  6. Kurzban, R. O., Aktipis, C. A. 2006.  Modular minds, multiple motives.  Shaller, M; Simpson, J & Kenrick, D. (Eds.) Evolution and Social Psychology, 39-53.  New York: Psychology Press.