{"id":28,"date":"2022-01-12T18:31:39","date_gmt":"2022-01-12T18:31:39","guid":{"rendered":"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/?page_id=28"},"modified":"2022-06-20T21:19:55","modified_gmt":"2022-06-20T21:19:55","slug":"technology","status":"publish","type":"page","link":"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/technology\/","title":{"rendered":"Technology"},"content":{"rendered":"\n<div id=\"unityblocks-hero\" class=\"wp-block-unityblocks-hero\" data-herotype=\"heading-hero\" data-image=\"{&quot;url&quot;:&quot;https:\/\/biodesign.asu.edu\/applied-structural-discovery\/wp-content\/uploads\/sites\/6\/2022\/02\/ASD_WebBanner-1920-512.jpg&quot;,&quot;altText&quot;:&quot;&quot;,&quot;cssClass&quot;:[],&quot;size&quot;:&quot;medium&quot;}\" data-subtitle=\"{&quot;text&quot;:&quot;&quot;,&quot;highlightColor&quot;:&quot;white&quot;,&quot;maxWidth&quot;:&quot;&quot;,&quot;cssClass&quot;:[]}\" data-title=\"{&quot;text&quot;:&quot;Center for Applied Structural Discovery&quot;,&quot;highlightColor&quot;:&quot;gold&quot;,&quot;maxWidth&quot;:&quot;&quot;,&quot;cssClass&quot;:[]}\" data-contents=\"[{&quot;text&quot;:&quot;&quot;,&quot;maxWidth&quot;:&quot;&quot;,&quot;cssClass&quot;:[],&quot;highlightColor&quot;:&quot;white&quot;}]\" data-contentscolor=\"white\"><\/div>\n\n\n<div class=\"wp-bootstrap-blocks-container container mb-0\">\n\t\n<div class=\"wp-bootstrap-blocks-row row mt-4 mb-5\">\n\t\n\n<div class=\"col-12\">\n\t\t\t\n<div class=\"yoast-breadcrumbs\"><span><span><a href=\"https:\/\/biodesign.asu.edu\/our-centers\/\">Our Centers<\/a><\/span> \/ <span><a href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/\">Applied Structural Discovery<\/a><\/span> \/ <span class=\"breadcrumb_last\" aria-current=\"page\">Technology<\/span><\/span><\/div>\n\t<\/div>\n\n<\/div>\n\n\n<div class=\"wp-bootstrap-blocks-row row justify-content-between\">\n\t\n\n<div class=\"col-12 col-md-3 mb-6\">\n\t\t\t\n<div aria-controls=\"sidebar-applied-structural-discovery\" aria-expanded=\"false\" class=\"sidebar-toggler\" data-target=\"#sidebar-applied-structural-discovery\" data-toggle=\"collapse\"><p>Select Section <\/p><span class=\"fas fa-chevron-up\" \/><\/div><nav class=\"sidebar collapse\" id=\"sidebar-applied-structural-discovery\" aria-label=\"Secondary\"> <div class=\"nav-link-container\"><a id=\"menu-item-69\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-home nav-link\">Overview<\/a><\/div><\/li>\n <div class=\"nav-link-container\"><a id=\"menu-item-35\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/research\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page nav-link\">Research<\/a><\/div><\/li>\n <div class=\"nav-link-container\"><a id=\"menu-item-34\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/team\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page nav-link\">Team<\/a><\/div><\/li>\n <div class=\"nav-link-container\"><a id=\"menu-item-33\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/technology\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page nav-link\">Technology<\/a><\/div><\/li>\n <div class=\"nav-link-container\"><a id=\"menu-item-97\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/news\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page nav-link\">News<\/a><\/div><\/li>\n <div class=\"nav-link-container\"><a id=\"menu-item-31\" href=\"https:\/\/biodesign.asu.edu\/applied-structural-discovery\/opportunities\/\" class=\"menu-item menu-item-type-post_type menu-item-object-page nav-link\">Opportunities<\/a><\/div><\/li>\n<\/nav>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-8\">\n\t\t\t\n\n<h2 class=\"mt-0 wp-block-heading\">Technology<\/h2>\n\n\n\n<p>Over the past three decades, director Petra Fromme has worked diligently to discover structures of proteins, which are the molecular machines of life, leading to a number of ground-breaking discoveries. Two of these discoveries were the first high resolution images of the structures of the Photosystem I and Photosystem II proteins, which are essential to the process of photosynthesis and its ability to sustain all life by being the most prolific solar energy converter on the planet.<\/p>\n\n\n\n<p>Upon joining ASU in 2002, Fromme teamed up with some current members of our center and a team of distinguished international collaborators to pioneer a new technique called serial femtosecond nanocrystallograpy, which has the potential to create high resolution movies of some of life\u2019s most mysterious processes.\u202fSuch information is critical in developing more effective healthcare treatments, preventing ruthless diseases, and building inexpensive and robust solar energy conversion systems to sustain humanity and our planet.<\/p>\n\n\n\n<h3 class=\"mt-6 wp-block-heading\">Core techniques used to interrogate molecular structures<\/h3>\n\n\n\n<ul class=\"uds-list\"><li>Femtosecond X-ray diffraction:\u202fUltra-short pulses of uniform, extraordinarily powerful x-rays are used to observe the movements of molecules as they work. We are actively developing this technique, which makes it easier to make submicroscopic (0.0001\u22120.01 mm) 3-D crystals of the molecule and is imaged at room temperature.&nbsp;<\/li><li>Ultrafast X-ray science:\u202fUltra-short pulses of uniform, powerful X-rays are used to unravel fundamental knowledge of the chemical and physical properties of molecules.&nbsp;<\/li><li>Nuclear magnetic resonance:\u202fHigh energy magnetic fields and radio waves are used to probe individual molecules in a more natural setting that can reveal a molecule&#8217;s full range of motion.&nbsp;<\/li><li>Spectroscopy: Light with energies ranging from the visible to X-rays is used to stimulate the desired state of a molecule or to determine information in real time on its structure, energetics, chemical and physical nature.&nbsp;<\/li><li>Computational methods:\u202fCutting-edge computational methodologies are developed to analyze and process enormous amounts of complex data.&nbsp;<\/li><\/ul>\n\n\n\n<h3 class=\"mt-6 wp-block-heading\">Global challenge focus areas&nbsp;&nbsp;<\/h3>\n\n\n\n<ul class=\"uds-list\"><li>Solar energy and photosynthesis:\u202fThe knowledge gained about photosynthesis will be used to improve photosynthesis in genetically engineered algae and to design more stable artificial systems that can inexpensively capture and store solar energy.&nbsp;<\/li><li>Health care and biomedicine:\u202fThe knowledge gained about molecules related to disease and medicine will be used to develop new treatments for cancer, cystic fibrosis, infectious diseases and other dangerous pathogens.&nbsp;<\/li><li>Technology development:\u202fNew technologies will be developed to discover significant insights into life\u2019s biggest mysteries and to make products useful to our global economy.<\/li><\/ul>\n\n\t<\/div>\n\n<\/div>\n\n<\/div>\n\n\n<section class=\"uds-section media-file inner-bg-none text-white gl-gray-7\" style=\"background: url(https:\/\/biodesign.asu.edu\/applied-structural-discovery\/wp-content\/uploads\/sites\/6\/2022\/02\/Applied-Structural-Discovery.jpg) center \/ cover no-repeat;\" >\n<div class=\"wp-bootstrap-blocks-container container mb-0\">\n\t\n\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\"><div class=\"wp-bootstrap-blocks-container container mb-0\">\n\t\n<div class=\"wp-bootstrap-blocks-row row justify-content-between my-6 my-xl-12\">\n\t\n\n<div class=\"col-12 col-md-8\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\">Support the Biodesign Center for Applied Structural Discovery<\/h2>\n\n\n\n<p class=\"lead text-white\">Using revolutionary techniques to uncover fundamental biological processes and make visionary discoveries impacting bioenergy, enzyme catalysis and drug discovery.<\/p>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-md-4 d-flex align-items-center justify-content-start justify-content-md-end\">\n\t\t\t\n\n\t<div class=\"uds-button \">\n\n\t\t\t\n\t\t\t<a href=\"https:\/\/www.asufoundation.org\/colleges-and-programs\/programs-and-centers\/biodesign-institute\/biodesign-center-for-applied-structural-discovery-CA110214.html\" class=\"btn  btn-gold \"   >Support<\/a>\n\t\n\t\t<\/div>\n\n\t<\/div>\n\n<\/div>\n\n<\/div>\n<\/div>\n\n<\/div>\n\n<\/section>","protected":false},"excerpt":{"rendered":"","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"uds_featured_image":null,"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Technology | Appliced Structural Discovery | ASU Biodesign Institute<\/title>\n<meta name=\"description\" content=\"The center has pioneered new technology to develop effective healthcare treatments, prevent disease, and build solar energy conversion systems to sustain humanity.\" \/>\n<meta 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