Publications

Below are links to the publications from each of the faculty in the Center for Applied Structural Discovery

Selected Publications

 

2018

  1. Hansen, D. T.; Craciunescu, F. M.; Fromme, P.; Johnston, S. A., Sykes, K. F., Generation of High Specificity Antibodies against Membrane Proteins Using DNA-Gold Micronanoplexes for Gene Gun Immunization. Current Protocols in Protein Science 2018, UNIT 29.20. DOI: 10.1002/cpps.50

  2. Jankovich, J. K.; Chapman, D.; Hansen, D. T.; Robida, M. D.; Loskutov, A.; Craciunescu, F.; Borovkov, A.; Kibler, K.; Goatley, L.; King, K.; Netherton, C. L.; Taylor, G.; Jacobs, B.; Sykes, K.; Dixon, L. K., Immunisation of pigs by DNA prime and recombinant vaccinia virus boost to identify and rank African swine fever virus immunogenic and protective proteins. J. Virol. 2018. DOI: 10.1128/JVI.02219-17

  3. Lee, Dan Bi, Jong-Min Kim, Jong Hyeon Seok, Ji-Hye Lee, Jae Deok Jo, Ji Young Mun, Chelsie Conrad et al. "Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography." Scientific reports 8, no. 1 (2018): 2541


2017

  1. Kupitz, Christopher, Jose L. Olmos Jr, Mark Holl, Lee Tremblay, Kanupriya Pande, Suraj Pandey, Dominik Oberthür et al. "Structural enzymology using X-ray free electron lasers." Structural Dynamics 4, no. 4 (2017): 044003

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  3. Reddy, Hemanth KN, Chun Hong Yoon, Andrew Aquila, Salah Awel, Kartik Ayyer, Anton Barty, Peter Berntsen et al. "Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source." Scientific data 4 (2017): 170079
  4. Ishigami, Izumi, Nadia A. Zatsepin, Masahide Hikita, Chelsie E. Conrad, Garrett Nelson, Jesse D. Coe, Shibom Basu et al. "Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature." Proceedings of the National Academy of Sciences 114, no. 30 (2017): 8011-8016
  5. Martin-Garcia, Jose M., Chelsie E. Conrad, Garrett Nelson, Natasha Stander, Nadia A. Zatsepin, James Zook, Lan Zhu et al. "Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation." IUCrJ 4, no. 4 (2017): 439-454
  6. Dods, Robert, Petra Båth, David Arnlund, Kenneth R. Beyerlein, Garrett Nelson, Mengling Liang, Rajiv Harimoorthy et al. "From Macrocrystals to Microcrystals: A Strategy for Membrane Protein Serial Crystallography." Structure 25, no. 9 (2017): 1461-1468
  7. Spence, J. C. H. "XFELs for structure and dynamics in biology." IUCrJ 4, no. 4 (2017).
  8. Stagno, J. R., Y. Liu, Y. R. Bhandari, C. E. Conrad, S. Panja, M. Swain, L. Fan et al. "Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography." Nature541, no. 7636 (2017): 242
  9. Sabbar, Mazyar, Henry Timmers, Yi-Jen Chen, Allison K. Pymer, Zhi-Heng Loh, Scott G. Sayres, Stefan Pabst, Robin Santra, and Stephen R. Leone. "State-resolved attosecond reversible and irreversible dynamics in strong optical fields." Nature Physics 13, no. 5 (2017): 472.
  10. Ishchenko, Andrii, Daniel Wacker, Mili Kapoor, Ai Zhang, Gye Won Han, Shibom Basu, Nilkanth Patel et al. "Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody." Proceedings of the National Academy of Sciences 114, no. 31 (2017): 8223-8228.
  11. Mazor, Yuval, Hila Toporik, and Su Lin. "Identification of Red Pigments in the Photosystem I Complex of Oxygenic Photosynthesis." Biophysical Journal 114, no. 3 (2018): 522a
  12. Mazor, Yuval, Anna Borovikova, Ido Caspy, and Nathan Nelson. "Structure of the plant photosystem I supercomplex at 2.6 Å resolution." Nature plants 3, no. 3 (2017): 17014.
  13. Zhang, Haitao, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth Patel, Anastasiia Sadybekov et al. "Structural basis for selectivity and diversity in angiotensin II receptors." Nature 544, no. 7650 (2017): 327.
  14. Zhang, Haonan, Anna Qiao, Dehua Yang, Linlin Yang, Antao Dai, Chris De Graaf, Steffen Reedtz-Runge et al. "Structure of the full-length glucagon class B G-protein-coupled receptor." Nature 546, no. 7657 (2017): 259.
  15. Daurer, Benedikt J., Kenta Okamoto, Johan Bielecki, Filipe RNC Maia, Kerstin Mühlig, M. Marvin Seibert, Max F. Hantke et al. "Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses." IUCrJ 4, no. 3 (2017).
  16. Oberthuer, Dominik, Juraj Knoška, Max O. Wiedorn, Kenneth R. Beyerlein, David A. Bushnell, Elena G. Kovaleva, Michael Heymann et al. "Double-flow focused liquid injector for efficient serial femtosecond crystallography." Scientific reports 7 (2017): 44628.
  17. Deb, Arpan, William A. Johnson, Alexander P. Kline, Boston J. Scott, Lydia R. Meador, Dustin Srinivas, Jose M. Martin-Garcia et al. "Bacterial expression, correct membrane targeting and functional folding of the HIV-1 membrane protein Vpu using a periplasmic signal peptide." PloS one 12, no. 2 (2017): e0172529.
  18. Hosseinizadeh, Ahmad, Ghoncheh Mashayekhi, Jeremy Copperman, Peter Schwander, Ali Dashti, Reyhaneh Sepehr, Russell Fung et al. "Conformational landscape of a virus by single-particle X-ray scattering." nAture methods 14, no. 9 (2017): 877.
  19. Sung, Yongjin, Rajiv Gupta, Brandon Nelson, Shuai Leng, Cynthia H. McCollough, and William S. Graves. "Phase-contrast imaging with a compact x-ray light source: system design." Journal of Medical Imaging 4, no. 4 (2017): 043503.
  20. Gisriel, Christopher, Iosifina Sarrou, Bryan Ferlez, John H. Golbeck, Kevin E. Redding, and Raimund Fromme. "Structure of a symmetric photosynthetic reaction center–photosystem." Science 357, no. 6355 (2017): 1021-1025.
  21. Perera, S. M. D. C., X. Xu, A. V. Struts, U. Chawla, S. Boutet, S. Carbajo, M. D. Seaberg et al. "Time-Resolved Wide-Angle X-Ray Scattering Reveals Protein Quake in Rhodopsin Activation." Biophysical Journal 112, no. 3 (2017): 506a-507a.
  22. Aryal, Rajindra P., Pieter Bas Kwak, Alfred G. Tamayo, Michael Gebert, Po-Lin Chiu, Thomas Walz, and Charles J. Weitz. "Macromolecular Assemblies of the Mammalian Circadian Clock." Molecular cell 67, no. 5 (2017): 770-782.
  23. Beiler, A. M., D. Khusnutdinova, B. L. Wadsworth, and G. F. Moore. "Cobalt Porphyrin–Polypyridyl Surface Coatings for Photoelectrosynthetic Hydrogen Production." Inorganic chemistry 56, no. 20 (2017): 12178-12185.
  24. Jones, Paul V., Gabriel L. Salmon, and Alexandra Ros. "Continuous Separation of DNA Molecules by Size Using Insulator-Based Dielectrophoresis." Analytical chemistry 89, no. 3 (2017): 1531-1539.
  25. Fristedt, Rikard, Chen Hu, Nicole Wheatley, Laura M. Roy, Rebekka M. Wachter, Linda Savage, Jeremy Harbinson et al. "RAF 2 is a RuBis CO assembly factor in Arabidopsis thaliana." The Plant Journal 94, no. 1 (2018): 146-156.
  26. Khusnutdinova, D., A. M. Beiler, B. L. Wadsworth, S. I. Jacob, and G. F. Moore. "Metalloporphyrin-modified semiconductors for solar fuel production." Chemical science 8, no. 1 (2017): 253-259.

2016

  1. Beiler, A. M.; Khusnutdinova, D.; Jacob, S. I.; Moore, G. F., Solar Hydrogen Production using Molecular Catalysts Immobilized on Gallium Phosphide (111)A and (111)B Polymer-Modified Photocathodes. ACS Applied Materials & Interfaces 2016. DOI: 10.1021/acsami.6b01557

  2. Hansen, D. T.; Robida, M. D.; Craciunescu, F. M.; Loskutov, A. V.; Dörner, K.; Rodenberry, J.-C.; Wang, X.; Olson, T. L.; Patel, H.; Fromme, P.; Sykes, K. F., Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization. Scientific Reports 2016, 6, 21925.
     
  3. Ayyer, K.; Yefanov, O. M.; Oberthür, D.; Roy-Chowdhury, S.; Galli, L.; Mariani, V.; Basu, S.; Coe, J.; Conrad, C. E.; Fromme, R.; Schaffer, A.; Dörner, K.; James, D.; Kupitz, C.; Metz, M.; Nelson, G.; Xavier, P. L.; Beyerlein, K. R.; Schmidt, M.; Sarrou, I.; Spence, J. C. H.; Weierstall, U.; White, T. A.; Yang, J.-H.; Zhao, Y.; Liang, M.; Aquila, A.; Hunter, M. S.; Robinson, J. S.; Koglin, J. E.; Boutet, S.; Fromme, P.; Barty, A.; Chapman, H. N., Macromolecular diffractive imaging using imperfect crystals. Nature 2016, 530 (7589), 202-206

2015

  1. Li, D.; Stansfeld, P. J.; Sansom, M. S. P.; Keogh, A.; Vogeley, L.; Howe, N.; Lyons, J. A.; Aragao, D.; Fromme, P.; Fromme, R.; Basu, S.; Grotjohann, I.; Kupitz, C.; Rendek, K.; Weierstall, U.; Zatsepin, N. A.; Cherezov, V.; Liu, W.; Bandaru, S.; English, N. J.; Gati, C.; Barty, A.; Yefanov, O.; Chapman, H. N.; Diederichs, K.; Messerschmidt, M.; Boutet, S.; Williams, G. J.; Marvin Seibert, M.; Caffrey, M., Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nat Commun 2015, 6.
     
  2. Kang, Y.; Zhou, X. E.; Gao, X.; He, Y.; Liu, W.; Ishchenko, A.; Barty, A.; White, T. A.; Yefanov, O.; Han, G. W.; Xu, Q.; de Waal, P. W.; Ke, J.; Tan, M. H. E.; Zhang, C.; Moeller, A.; West, G. M.; Pascal, B. D.; Van Eps, N.; Caro, L. N.; Vishnivetskiy, S. A.; Lee, R. J.; Suino-Powell, K. M.; Gu, X.; Pal, K.; Ma, J.; Zhi, X.; Boutet, S.; Williams, G. J.; Messerschmidt, M.; Gati, C.; Zatsepin, N. A.; Wang, D.; James, D.; Basu, S.; Roy-Chowdhury, S.; Conrad, C. E.; Coe, J.; Liu, H.; Lisova, S.; Kupitz, C.; Grotjohann, I.; Fromme, R.; Jiang, Y.; Tan, M.; Yang, H.; Li, J.; Wang, M.; Zheng, Z.; Li, D.; Howe, N.; Zhao, Y.; Standfuss, J.; Diederichs, K.; Dong, Y.; Potter, C. S.; Carragher, B.; Caffrey, M.; Jiang, H.; Chapman, H. N.; Spence, J. C. H.; Fromme, P.; Weierstall, U.; Ernst, O. P.; Katritch, V.; Gurevich, V. V.; Griffin, P. R.; Hubbell, W. L.; Stevens, R. C.; Cherezov, V.; Melcher, K.; Xu, H. E., Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 2015, doi:10.1038/nature14656
  3. Zook, J.; Mo, G.; Sisco, Nicholas J.; Craciunescu, Felicia M.; Hansen, Debra T.; Baravati, B.; Cherry, Brian R.; Sykes, K.; Wachter, R.; Van Horn, Wade D.; Fromme, P., NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins. Structure 2015, 23 (6), 1116-1122.
     
  4. Zhang, H.; Unal, H.; Gati, C.; Han, Gye W.; Liu, W.; Zatsepin, Nadia A.; James, D.; Wang, D.; Nelson, G.; Weierstall, U.; Sawaya, Michael R.; Xu, Q.; Messerschmidt, M.; Williams, Garth J.; Boutet, S.; Yefanov, Oleksandr M.; White, Thomas A.; Wang, C.; Ishchenko, A.; Tirupula, Kalyan C.; Desnoyer, R.; Coe, J.; Conrad, Chelsie E.; Fromme, P.; Stevens, Raymond C.; Katritch, V.; Karnik, Sadashiva S.; Cherezov, V., Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography. Cell 2015, doi:10.1016/j.cell.2015.04.011.
     
  5. Fenalti, G.; Zatsepin, N. A.; Betti, C.; Giguere, P.; Han, G. W.; Ishchenko, A.; Liu, W.; Guillemyn, K.; Zhang, H.; James, D.; Wang, D.; Weierstall, U.; Spence, J. C. H.; Boutet, S.; Messerschmidt, M.; Williams, G. J.; Gati, C.; Yefanov, O. M.; White, T. A.; Oberthuer, D.; Metz, M.; Yoon, C. H.; Barty, A.; Chapman, H. N.; Basu, S.; Coe, J.; Conrad, C. E.; Fromme, R.; Fromme, P.; Tourwé, D.; Schiller, P. W.; Roth, B. L.; Ballet, S.; Katritch, V.; Stevens, R. C.; Cherezov, V., Structural basis for bifunctional peptide recognition at human δ-opioid receptor. Nat Struct Mol Biol 2015, 22 (3), 265-268.

2014

  1. Tenboer, J.; Basu, S.; Zatsepin, N.; Pande, K.; Milathianaki, D.; Frank, M.; Hunter, M.; Boutet, S.; Williams, G. J.; Koglin, J. E.; Oberthuer, D.; Heymann, M.; Kupitz, C.; Conrad, C.; Coe, J.; Roy-Chowdhury, S.; Weierstall, U.; James, D.; Wang, D.; Grant, T.; Barty, A.; Yefanov, O.; Scales, J.; Gati, C.; Seuring, C.; Srajer, V.; Henning, R.; Schwander, P.; Fromme, R.; Ourmazd, A.; Moffat, K.; Van Thor, J. J.; Spence, J. C. H.; Fromme, P.; Chapman, H. N.; Schmidt, M., Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science 2014, 346 (6214), 1242-1246.
     
  2. Wang, D.; Fu, L.; Ning, W.; Guo, L.; Sun, X.; Dey, S. K.; Chaturvedi, R.; Wilson, K. T.; DuBois, R. N., Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth. Proceedings of the National Academy of Sciences 2014, 111 (19), 7084-7089.
     
  3. Kupitz, C.; Basu, S.; Grotjohann, I.; Fromme, R.; Zatsepin, N. A.; Rendek, K. N.; Hunter, M. S.; Shoeman, R. L.; White, T. A.; Wang, D.; James, D.; Yang, J.-H.; Cobb, D. E.; Reeder, B.; Sierra, R. G.; Liu, H.; Barty, A.; Aquila, A. L.; Deponte, D.; Kirian, R. A.; Bari, S.; Bergkamp, J. J.; Beyerlein, K. R.; Bogan, M. J.; Caleman, C.; Chao, T.-C.; Conrad, C. E.; Davis, K. M.; Fleckenstein, H.; Galli, L.; Hau-Riege, S. P.; Kassemeyer, S.; Laksmono, H.; Liang, M.; Lomb, L.; Marchesini, S.; Martin, A. V.; Messerschmidt, M.; Milathianaki, D.; Nass, K.; Ros, A.; Roy-Chowdhury, S.; Schmidt, K.; Seibert, M.; Steinbrener, J.; Stellato, F.; Yan, L.; Yoon, C.; Moore, T. A.; Moore, A. L.; Pushkar, Y.; Williams, G. J.; Boutet, S.; Doak, R. B.; Weierstall, U.; Frank, M.; Chapman, H. N.; Spence, J. C. H.; Fromme, P., Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature 2014, 513 (7517), 261-265.
     
  4. Weierstall, U.; James, D.; Wang, C.; White, T. A.; Wang, D.; Liu, W.; Spence, J. C. H.; Bruce Doak, R.; Nelson, G.; Fromme, P.; Fromme, R.; Grotjohann, I.; Kupitz, C.; Zatsepin, N. A.; Liu, H.; Basu, S.; Wacker, D.; Won Han, G.; Katritch, V.; Boutet, S.; Messerschmidt, M.; Williams, G. J.; Koglin, J. E.; Marvin Seibert, M.; Klinker, M.; Gati, C.; Shoeman, R. L.; Barty, A.; Chapman, H. N.; Kirian, R. A.; Beyerlein, K. R.; Stevens, R. C.; Li, D.; Shah, S. T. A.; Howe, N.; Caffrey, M.; Cherezov, V., Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun 2014, 5.
     
  5. Arnlund, D.; Johansson, L. C.; Wickstrand, C.; Barty, A.; Williams, G. J.; Malmerberg, E.; Davidsson, J.; Milathianaki, D.; DePonte, D. P.; Shoeman, R. L.; Wang, D.; James, D.; Katona, G.; Westenhoff, S.; White, T. A.; Aquila, A.; Bari, S.; Berntsen, P.; Bogan, M.; van Driel, T. B.; Doak, R. B.; Kjaer, K. S.; Frank, M.; Fromme, R.; Grotjohann, I.; Henning, R.; Hunter, M. S.; Kirian, R. A.; Kosheleva, I.; Kupitz, C.; Liang, M.; Martin, A. V.; Nielsen, M. M.; Messerschmidt, M.; Seibert, M. M.; Sjohamn, J.; Stellato, F.; Weierstall, U.; Zatsepin, N. A.; Spence, J. C. H.; Fromme, P.; Schlichting, I.; Boutet, S.; Groenhof, G.; Chapman, H. N.; Neutze, R., Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nat Meth 2014, 11 (9), 923-926.
     
  6. Liu, W.; Ishchenko, A.; Cherezov, V., Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography. Nat. Protocols 2014, 9 (9), 2123-2134.
     
  7. Gong, Z.; Kessans, S. A.; Song, L.; Dörner, K.; Lee, H.-H.; Meador, L. R.; LaBaer, J.; Hogue, B. G.; Mor, T. S.; Fromme, P., Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41. Protein Science 2014, 23 (11), 1607-1618.
     
  8. Lee, H.-H.; Cherni, I.; Yu, H. Q.; Fromme, R.; Doran, J. D.; Grotjohann, I.; Mittman, M.; Basu, S.; Deb, A.; Dorner, K.; Aquila, A.; Barty, A.; Boutet, S.; Chapman, H. N.; Doak, R. B.; Hunter, M. S.; James, D.; Kirian, R. A.; Kupitz, C.; Lawrence, R. M.; Liu, H.; Nass, K.; Schlichting, I.; Schmidt, K. E.; Seibert, M. M.; Shoeman, R. L.; Spence, J. C. H.; Stellato, F.; Weierstall, U.; Williams, G. J.; Yoon, C.; Wang, D.; Zatsepin, N. A.; Hogue, B. G.; Matoba, N.; Fromme, P.; Mor, T. S., Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. IUCrJ 2014, 1 (5), 305-317.
  9. Krawicz, A.; Cedeno, D.; Moore, G. F., Energetics and efficiency analysis of a cobaloxime-modified semiconductor under simulated air mass 1.5 illumination. Physical Chemistry Chemical Physics 2014, 16 (30), 15818-15824.
     
  10. Cedeno, D.; Krawicz, A.; Doak, P.; Yu, M.; Neaton, J. B.; Moore, G. F., Using Molecular Design to Control the Performance of Hydrogen-Producing Polymer-Brush-Modified Photocathodes. The Journal of Physical Chemistry Letters 2014, 5 (18), 3222-3226.
     
  11. Sayres, S. G.; Hosler, E. R.; Leone, S. R., Exposing the Role of Electron Correlation in Strong-Field Double Ionization: X-ray Transient Absorption of Orbital Alignment in Xe+ and Xe2+. The Journal of Physical Chemistry A 2014, 118 (37), 8614-8624.

2013

  1. Liu, W.; Wacker, D.; Gati, C.; Han, G. W.; James, D.; Wang, D.; Nelson, G.; Weierstall, U.; Katritch, V.; Barty, A.; Zatsepin, N. A.; Li, D.; Messerschmidt, M.; Boutet, S.; Williams, G. J.; Koglin, J. E.; Seibert, M. M.; Wang, C.; Shah, S. T. A.; Basu, S.; Fromme, R.; Kupitz, C.; Rendek, K. N.; Grotjohann, I.; Fromme, P.; Kirian, R. A.; Beyerlein, K. R.; White, T. A.; Chapman, H. N.; Caffrey, M.; Spence, J. C. H.; Stevens, R. C.; Cherezov, V., Serial Femtosecond Crystallography of G Protein–Coupled Receptors. Science 2013, 342 (6165), 1521-1524.
     
  2. Martin, A. V.; Morgan, A. J.; Ekeberg, T.; Loh, N. D.; Maia, F. R. N. C.; Wang, F.; Spence, J. C. H.; Chapman, H. N., The extraction of single-particle diffraction patterns from a multiple-particle diffraction pattern. Optics express 2013, 21 (13), 15102-15112.
     
  3. Redecke, L.; Nass, K.; DePonte, D. P.; White, T. A.; Rehders, D.; Barty, A.; Stellato, F.; Liang, M.; Barends, T. R. M.; Boutet, S.; Williams, G. J.; Messerschmidt, M.; Seibert, M. M.; Aquila, A.; Arnlund, D.; Bajt, S.; Barth, T.; Bogan, M. J.; Caleman, C.; Chao, T.-C.; Doak, R. B.; Fleckenstein, H.; Frank, M.; Fromme, R.; Galli, L.; Grotjohann, I.; Hunter, M. S.; Johansson, L. C.; Kassemeyer, S.; Katona, G.; Kirian, R. A.; Koopmann, R.; Kupitz, C.; Lomb, L.; Martin, A. V.; Mogk, S.; Neutze, R.; Shoeman, R. L.; Steinbrener, J.; Timneanu, N.; Wang, D.; Weierstall, U.; Zatsepin, N. A.; Spence, J. C. H.; Fromme, P.; Schlichting, I.; Duszenko, M.; Betzel, C.; Chapman, H. N., Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser. Science 2013, 339 (6116), 227-230.
     
  4. Johansson, L. C.; Arnlund, D.; Katona, G.; White, T. A.; Barty, A.; DePonte, D. P.; Shoeman, R. L.; Wickstrand, C.; Sharma, A.; Williams, G. J.; Aquila, A.; Bogan, M. J.; Caleman, C.; Davidsson, J.; Doak, R. B.; Frank, M.; Fromme, R.; Galli, L.; Grotjohann, I.; Hunter, M. S.; Kassemeyer, S.; Kirian, R. A.; Kupitz, C.; Liang, M.; Lomb, L.; Malmerberg, E.; Martin, A. V.; Messerschmidt, M.; Nass, K.; Redecke, L.; Seibert, M. M.; Sjöhamn, J.; Steinbrener, J.; Stellato, F.; Wang, D.; Wahlgren, W. Y.; Weierstall, U.; Westenhoff, S.; Zatsepin, N. A.; Boutet, S.; Spence, J. C. H.; Schlichting, I.; Chapman, H. N.; Fromme, P.; Neutze, R., Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. Nat Commun 2013, 4.
     
  5. Krawicz, A.; Yang, J.; Anzenberg, E.; Yano, J.; Sharp, I. D.; Moore, G. F., Photofunctional Construct That Interfaces Molecular Cobalt-Based Catalysts for H2 Production to a Visible-Light-Absorbing Semiconductor. Journal of the American Chemical Society 2013, 135 (32), 11861-11868.
     
  6. Abdallah, B. G.; Chao, T.-C.; Kupitz, C.; Fromme, P.; Ros, A., Dielectrophoretic Sorting of Membrane Protein Nanocrystals. ACS Nano 2013, 7 (10), 9129-9137.
     
  7. Katoh, H.; Wang, D.; Daikoku, T.; Sun, H.; Dey, Sudhansu K.; DuBois, Raymond N., CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis. Cancer Cell 2013, 24 (5), 631-644.

2012

  1. Koopmann, R.; Cupelli, K.; Redecke, L.; Nass, K.; DePonte, D. P.; White, T. A.; Stellato, F.; Rehders, D.; Liang, M.; Andreasson, J.; Aquila, A.; Bajt, S.; Barthelmess, M.; Barty, A.; Bogan, M. J.; Bostedt, C.; Boutet, S.; Bozek, J. D.; Caleman, C.; Coppola, N.; Davidsson, J.; Doak, R. B.; Ekeberg, T.; Epp, S. W.; Erk, B.; Fleckenstein, H.; Foucar, L.; Graafsma, H.; Gumprecht, L.; Hajdu, J.; Hampton, C. Y.; Hartmann, A.; Hartmann, R.; Hauser, G.; Hirsemann, H.; Holl, P.; Hunter, M. S.; Kassemeyer, S.; Kirian, R. A.; Lomb, L.; Maia, F. R. N. C.; Kimmel, N.; Martin, A. V.; Messerschmidt, M.; Reich, C.; Rolles, D.; Rudek, B.; Rudenko, A.; Schlichting, I.; Schulz, J.; Seibert, M. M.; Shoeman, R. L.; Sierra, R. G.; Soltau, H.; Stern, S.; Struder, L.; Timneanu, N.; Ullrich, J.; Wang, X.; Weidenspointner, G.; Weierstall, U.; Williams, G. J.; Wunderer, C. B.; Fromme, P.; Spence, J. C. H.; Stehle, T.; Chapman, H. N.; Betzel, C.; Duszenko, M., In vivo protein crystallization opens new routes in structural biology. Nat Meth 2012, 9 (3), 259-262.
     
  2. Boutet, S.; Lomb, L.; Williams, G. J.; Barends, T. R. M.; Aquila, A.; Doak, R. B.; Weierstall, U.; DePonte, D. P.; Steinbrener, J.; Shoeman, R. L.; Messerschmidt, M.; Barty, A.; White, T. A.; Kassemeyer, S.; Kirian, R. A.; Seibert, M. M.; Montanez, P. A.; Kenney, C.; Herbst, R.; Hart, P.; Pines, J.; Haller, G.; Gruner, S. M.; Philipp, H. T.; Tate, M. W.; Hromalik, M.; Koerner, L. J.; van Bakel, N.; Morse, J.; Ghonsalves, W.; Arnlund, D.; Bogan, M. J.; Caleman, C.; Fromme, R.; Hampton, C. Y.; Hunter, M. S.; Johansson, L. C.; Katona, G.; Kupitz, C.; Liang, M.; Martin, A. V.; Nass, K.; Redecke, L.; Stellato, F.; Timneanu, N.; Wang, D.; Zatsepin, N. A.; Schafer, D.; Defever, J.; Neutze, R.; Fromme, P.; Spence, J. C. H.; Chapman, H. N.; Schlichting, I., High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography. Science 2012, 337 (6092), 362-364.
     
  3. Aquila, A.; Hunter, M. S.; Doak, R. B.; Kirian, R. A.; Fromme, P.; White, T. A.; Andreasson, J.; Arnlund, D.; Bajt, S. a.; Barends, T. R. M.; Barthelmess, M.; Bogan, M. J.; Bostedt, C.; Bottin, H.; Bozek, J. D.; Caleman, C.; Coppola, N.; Davidsson, J.; DePonte, D. P.; Elser, V.; Epp, S. W.; Erk, B.; Fleckenstein, H.; Foucar, L.; Frank, M.; Fromme, R.; Graafsma, H.; Grotjohann, I.; Gumprecht, L.; Hajdu, J.; Hampton, C. Y.; Hartmann, A.; Hartmann, R.; Hau-Riege, S.; Hauser, G.; Hirsemann, H.; Holl, P.; Holton, J. M.; Hömke, A.; Johansson, L.; Kimmel, N.; Kassemeyer, S.; Krasniqi, F.; Kühnel, K.-U.; Liang, M.; Lomb, L.; Malmerberg, E.; Marchesini, S.; Martin, A. V.; Maia, F. R. N. C.; Messerschmidt, M.; Nass, K.; Reich, C.; Neutze, R.; Rolles, D.; Rudek, B.; Rudenko, A.; Schlichting, I.; Schmidt, C.; Schmidt, K. E.; Schulz, J.; Seibert, M. M.; Shoeman, R. L.; Sierra, R.; Soltau, H.; Starodub, D.; Stellato, F.; Stern, S.; Strüder, L.; Timneanu, N.; Ullrich, J.; Wang, X.; Williams, G. J.; Weidenspointner, G.; Weierstall, U.; Wunderer, C.; Barty, A.; Spence, J. C. H.; Chapman, H. N., Time-resolved protein nanocrystallography using an X-ray free-electron laser. Optics Express 2012, 20 (3), 2706-2716.
     
  4. Johansson, L. C.; Arnlund, D.; White, T. A.; Katona, G.; DePonte, D. P.; Weierstall, U.; Doak, R. B.; Shoeman, R. L.; Lomb, L.; Malmerberg, E.; Davidsson, J.; Nass, K.; Liang, M.; Andreasson, J.; Aquila, A.; Bajt, S.; Barthelmess, M.; Barty, A.; Bogan, M. J.; Bostedt, C.; Bozek, J. D.; Caleman, C.; Coffee, R.; Coppola, N.; Ekeberg, T.; Epp, S. W.; Erk, B.; Fleckenstein, H.; Foucar, L.; Graafsma, H.; Gumprecht, L.; Hajdu, J.; Hampton, C. Y.; Hartmann, R.; Hartmann, A.; Hauser, G.; Hirsemann, H.; Holl, P.; Hunter, M. S.; Kassemeyer, S.; Kimmel, N.; Kirian, R. A.; Maia, F. R. N. C.; Marchesini, S.; Martin, A. V.; Reich, C.; Rolles, D.; Rudek, B.; Rudenko, A.; Schlichting, I.; Schulz, J.; Seibert, M. M.; Sierra, R. G.; Soltau, H.; Starodub, D.; Stellato, F.; Stern, S.; Struder, L.; Timneanu, N.; Ullrich, J.; Wahlgren, W. Y.; Wang, X.; Weidenspointner, G.; Wunderer, C.; Fromme, P.; Chapman, H. N.; Spence, J. C. H.; Neutze, R., Lipidic phase membrane protein serial femtosecond crystallography. Nat Meth 2012, 9 (3), 263-265.
     
  5. Liu, W.; Chun, E.; Thompson, A. A.; Chubukov, P.; Xu, F.; Katritch, V.; Han, G. W.; Roth, C. B.; Heitman, L. H.; IJzerman, A. P.; Cherezov, V.; Stevens, R. C., Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions. Science 2012, 337 (6091), 232-236.
     
  6. Barty, A.; Caleman, C.; Aquila, A.; Timneanu, N.; Lomb, L.; White, T. A.; Andreasson, J.; Arnlund, D.; Bajt, S.; Barends, T. R. M.; Barthelmess, M.; Bogan, M. J.; Bostedt, C.; Bozek, J. D.; Coffee, R.; Coppola, N.; Davidsson, J.; DePonte, D. P.; Doak, R. B.; Ekeberg, T.; Elser, V.; Epp, S. W.; Erk, B.; Fleckenstein, H.; Foucar, L.; Fromme, P.; Graafsma, H.; Gumprecht, L.; Hajdu, J.; Hampton, C. Y.; Hartmann, R.; Hartmann, A.; Hauser, G.; Hirsemann, H.; Holl, P.; Hunter, M. S.; Johansson, L.; Kassemeyer, S.; Kimmel, N.; Kirian, R. A.; Liang, M.; Maia, F. R. N. C.; Malmerberg, E.; Marchesini, S.; Martin, A. V.; Nass, K.; Neutze, R.; Reich, C.; Rolles, D.; Rudek, B.; Rudenko, A.; Scott, H.; Schlichting, I.; Schulz, J.; Seibert, M. M.; Shoeman, R. L.; Sierra, R. G.; Soltau, H.; Spence, J. C. H.; Stellato, F.; Stern, S.; Struder, L.; Ullrich, J.; WangX; Weidenspointner, G.; Weierstall, U.; Wunderer, C. B.; Chapman, H. N., Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nat Photon 2012, 6 (1), 35-40.
     
  7. Xia, D.; Wang, D.; Kim, S.-H.; Katoh, H.; DuBois, R. N., Prostaglandin E2 promotes intestinal tumor growth via DNA methylation. Nat Med 2012, 18 (2), 224-226.
     
  8. Weierstall, U.; Spence, J. C. H.; Doak, R. B., Injector for scattering measurements on fully solvated biospecies. Review of scientific instruments 2012, 83 (3), 035108.
     
  9. White, T. A.; Kirian, R. A.; Martin, A. V.; Aquila, A.; Nass, K.; Barty, A.; Chapman, H. N., CrystFEL: a software suite for snapshot serial crystallography. Journal of Applied Crystallography 2012, 45 (2), 335-341.
     
  10. Thompson, A. A*.; Liu, W*.; Chun, E.; Katritch, V.; Wu, H.; Vardy, E.; Huang, X.-P.; Trapella, C.; Guerrini, R.; Calo, G.; Roth, B. L.; Cherezov, V.; Stevens, R. C., Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature 2012, 485 (7398), 395-399.
     
  11. Brunger, Axel T.; Adams, Paul D.; Fromme, P.; Fromme, R.; Levitt, M.; Schröder, Gunnar F., Improving the Accuracy of Macromolecular Structure Refinement at 7 Å Resolution. Structure 2012, 20 (6), 957-966.

2011

  1. Wang, D.; Ning, W.; Xie, D.; Guo, L.; DuBois, R. N., Peroxisome proliferator-activated receptor [delta] confers resistance to peroxisome proliferator-activated receptor [gamma]-induced apoptosis in colorectal cancer cells. Oncogene 2012, 31 (8), 1013-1023. 2011
     
  2. Chapman, H. N.; Fromme, P.; Barty, A.; White, T. A.; Kirian, R. A.; Aquila, A.; Hunter, M. S.; Schulz, J.; DePonte, D. P.; Weierstall, U.; Doak, R. B.; Maia, F. R. N. C.; Martin, A. V.; Schlichting, I.; Lomb, L.; Coppola, N.; Shoeman, R. L.; Epp, S. W.; Hartmann, R.; Rolles, D.; Rudenko, A.; Foucar, L.; Kimmel, N.; Weidenspointner, G.; Holl, P.; Liang, M.; Barthelmess, M.; Caleman, C.; Boutet, S.; Bogan, M. J.; Krzywinski, J.; Bostedt, C.; Bajt, S.; Gumprecht, L.; Rudek, B.; Erk, B.; Schmidt, C.; Homke, A.; Reich, C.; Pietschner, D.; Struder, L.; Hauser, G.; Gorke, H.; Ullrich, J.; Herrmann, S.; Schaller, G.; Schopper, F.; Soltau, H.; Kuhnel, K.-U.; Messerschmidt, M.; Bozek, J. D.; Hau-Riege, S. P.; Frank, M.; Hampton, C. Y.; Sierra, R. G.; Starodub, D.; Williams, G. J.; Hajdu, J.; Timneanu, N.; Seibert, M. M.; Andreasson, J.; Rocker, A.; Jonsson, O.; Svenda, M.; Stern, S.; Nass, K.; Andritschke, R.; Schroter, C.-D.; Krasniqi, F.; Bott, M.; Schmidt, K. E.; Wang, X.; Grotjohann, I.; Holton, J. M.; Barends, T. R. M.; Neutze, R.; Marchesini, S.; Fromme, R.; Schorb, S.; Rupp, D.; Adolph, M.; Gorkhover, T.; Andersson, I.; Hirsemann, H.; Potdevin, G.; Graafsma, H.; Nilsson, B.; Spence, J. C. H., Femtosecond X-ray protein nanocrystallography. Nature 2011, 470 (7332), 73-77.
     
  3. Seibert, M. M.; Ekeberg, T.; Maia, F. R. N. C.; Svenda, M.; Andreasson, J.; Jonsson, O.; Odic, D.; Iwan, B.; Rocker, A.; Westphal, D.; Hantke, M.; DePonte, D. P.; Barty, A.; Schulz, J.; Gumprecht, L.; Coppola, N.; Aquila, A.; Liang, M.; White, T. A.; Martin, A.; Caleman, C.; Stern, S.; Abergel, C.; Seltzer, V.; Claverie, J.-M.; Bostedt, C.; Bozek, J. D.; Boutet, S.; Miahnahri, A. A.; Messerschmidt, M.; Krzywinski, J.; Williams, G.; Hodgson, K. O.; Bogan, M. J.; Hampton, C. Y.; Sierra, R. G.; Starodub, D.; Andersson, I.; Bajt, S.; Barthelmess, M.; Spence, J. C. H.; Fromme, P.; Weierstall, U.; Kirian, R.; Hunter, M.; Doak, R. B.; Marchesini, S.; Hau-Riege, S. P.; Frank, M.; Shoeman, R. L.; Lomb, L.; Epp, S. W.; Hartmann, R.; Rolles, D.; Rudenko, A.; Schmidt, C.; Foucar, L.; Kimmel, N.; Holl, P.; Rudek, B.; Erk, B.; Homke, A.; Reich, C.; Pietschner, D.; Weidenspointner, G.; Struder, L.; Hauser, G.; Gorke, H.; Ullrich, J.; Schlichting, I.; Herrmann, S.; Schaller, G.; Schopper, F.; Soltau, H.; Kuhnel, K.-U.; Andritschke, R.; Schroter, C.-D.; Krasniqi, F.; Bott, M.; Schorb, S.; Rupp, D.; Adolph, M.; Gorkhover, T.; Hirsemann, H.; Potdevin, G.; Graafsma, H.; Nilsson, B.; Chapman, H. N.; Hajdu, J., Single mimivirus particles intercepted and imaged with an X-ray laser. Nature 2011, 470 (7332), 78-81.
     
  4. Spence, J. C. H.; Kirian, R. A.; Wang, X.; Weierstall, U.; Schmidt, K. E.; White, T.; Barty, A.; Chapman, H. N.; Marchesini, S.; Holton, J., Phasing of coherent femtosecond X-ray diffraction from size-varying nanocrystals. Optics express 2011, 19 (4), 2866-2873.
     
  5. Kirian, R. A.; White, T. A.; Holton, J. M.; Chapman, H. N.; Fromme, P.; Barty, A.; Lomb, L.; Aquila, A.; Maia, F. R. N. C.; Martin, A. V.; Fromme, R.; Wang, X.; Hunter, M. S.; Schmidt, K. E.; Spence, J. C. H., Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals. Acta Crystallographica Section A 2011, 67 (2), 131-140.
     
  6. Moore, G. F.; Blakemore, J. D.; Milot, R. L.; Hull, J. F.; Song, H.-e.; Cai, L.; Schmuttenmaer, C. A.; Crabtree, R. H.; Brudvig, G. W., A visible light water-splitting cell with a photoanode formed by codeposition of a high-potential porphyrin and an iridium water-oxidation catalyst. Energy & Environmental Science 2011, 4 (7), 2389-2392.

2010

  1. Kirian, R. A.; Wang, X.; Weierstall, U.; Schmidt, K. E.; Spence, J. C. H.; Hunter, M.; Fromme, P.; White, T.; Chapman, H. N.; Holton, J., Femtosecond protein nanocrystallography—data analysis methods. Optics express 2010, 18 (6), 5713-5723.
     
  2. Chien, E. Y. T.; Liu, W.; Zhao, Q.; Katritch, V.; Won Han, G.; Hanson, M. A.; Shi, L.; Newman, A. H.; Javitch, J. A.; Cherezov, V.; Stevens, R. C., Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist. Science 2010, 330 (6007), 1091-1095.
     
  3. Wang, D.; DuBois, R. N., Eicosanoids and cancer. Nat Rev Cancer 2010, 10 (3), 181-193.

Historical

  1. Spence, J. C. H.; Doak, R. B., Single molecule diffraction. Physical review letters 2004, 92 (19), 198102.