News & Events

  • "Toehold Switches: De-Novo-Designed Regulators of Gene Expression," A. A. Green, P. A. Silver, J. J. Collins, and P. Yin, Cell 159 925-939 (2014)
  • "Paper-based Synthetic Gene Networks," K. Pardee, A. A. Green, T. Ferrante, E. Cameron, A. DaleyKeyser, P. Yin, and J. J. Collins, Cell 159 940–954 (2014)

Reports in Scientific Journals:

  1. Nature News & Views: “Toehold gene switches make big footprints”, December 2014
  2. Nature Reviews Genetics Research Highlight on “Just add water — programmable in vitro diagnostics”, November 2014
  3. Nature Methods research highlight “De novo-designed riboregulators”, November 2014
  4. Nature Research highlight on “Paper-based gene tools”, October 2014
  5. Cell preview “Synthetic Biology Looks Good on Paper”, October 2014

Main Media Reports:

  1. BioTechniques article on “Bringing synthetic biology to (freeze-dried) paper”, December 2014
  2. The Daily Mail article on “The ‘game changing’ smart paper that could instantly test for Ebola”, November 2014
  3. CNET article on “Simple paper ‘litmus’ test detect disease, infection”, October 2014
  4. Newsweek article on “New Pocket-Sized Blotter Test Can Detect Ebola Strains in Just 30 Minutes”, October 2014
  5. io9 article on “This Remarkable Scrap of Paper Can Detect Ebola”, October 2014
  6. Tech Times article on “Scientists create a paper test that can detect Ebola in 30 minutes”, October 2014
  7. BBC News article on “Prototype paper test can detect Ebola strains”, October 2014
  8. MIT Technology Review article on “Synthetic Biologists Create Paper-Based Diagnostic for Ebola”, October 2014
  9. TheScientist article on “Next Generation: Freeze-Dried Gene Networks”, October 2014
  10. Wyss Institute Press Release:

Other Media Reports

  1. Genetic Literacy Project article on "Synthetic biology on a piece of paper: brighter future for disease diagnostics?" December 2014
  2. CBS Boston article on "Quicker ebola test method in the works" November 2014
  3. SciBX article on "Paperback diagnostics" November 2014
  4. Futurity article on "Paper circuit might diagnose ebola in the field" November 2014
  5. Government Technology article on "Harvard professor develops fast, cheap prototype ebola test" October 2014
  6. IEEE Spectrum article on "Printed dots detect ebola (and more) without a lab" October 2014
  7. International Business Times article on "You Can Detect Ebola In Just 30 Minutes With New Litmus Papers" October 2014
  8. IrishCentral article on "Ebola test in minutes is developed by Irish American Harvard scientist" October 2014
  9. The Gleaner article on "DNA-programmed paper can test For ebola" October 2014
  10. NextBigFuture article on "Paper strip tests for Ebola for 4 to 65 cents each" October 2014
  11. Breitbart article on "Scientists develop 30-minute, $20 ebola test using freeze-dried paper" October 2014
  12. article on "DNA-programmed paper can test for Ebola and a whole lot more" October 2014
  13. Co.Exist article on "This cheap paper test can tell you if you have ebola in just 30 minutes" October 2014
  14. article on "Cost-effective filter paper being developed to detect ebola" October 2014
  15. AskMen article on "DNA-programmed blotting paper test for ebola" October 2014
  16. Boston Herald article on "Harvard prof develops fast, cheap prototype Ebola test" October 2014
  17. Irish Examiner article on "Test could identify ebola in just 30 minutes" October 2014
  18. Inquisitr News article on "Ebola detected in minutes on cheap paper testing strips" October 2014
  19. RT News article on "Scientists create litmus-like paper Ebola tests taking 30 minutes" October 2014
  20. Design & Trend article on "Ebola paper test developed by Harvard scientists" October 2014
  21. Northern Voices Online article on "New ebola test takes 30 minutes, costs $20" October 2014
  22. shinyshiny article on "This new testing strip can detect Ebola, thanks to jellyfish" October 2014
  23. United Press International article on "New paper Ebola test can detect strains within 30 minutes" October 2014
  24. Headlines & Global News article on "Ebola could be detected in less than an hour with this pocket-sized piece of paper" October 2014
  25. Wall Street OTC article on "New test can diagnose ebola symptoms in 30 minutes" October 2014
  26. Daily Digest News article on "New inexpensive test can detect ebola in 30 minutes" October 2014
  27. CNBC article on "New test can spot Ebola in 30 minutes" October 2014
  28. Medical News Today article on "Cheap, fast 'paper strip' text for Ebola, other infections, steps closer" October 2014
  29. article on "Synthetic biology on ordinary paper" October 2014
  30. Science Codex article on "Paper-based synthetic gene networks could enable rapid detection of ebola" October 2014
  31. Medical Daily article on "Rapid ebola detection may soon be possible with freeze-dried gene networks" October 2014
  32. Nanowerk News article on "Synthetic biology on ordinary paper, results off the page" October 2014
  33. Digital Trends:
  34. R&D Mag:

SNIPRs take aim at disease-related mutations

February 27, 2020

A typo appearing in the draft of a novel is no great calamity. Nature, however, is often less forgiving of errors. A change in just one letter of the genetic code can have catastrophic consequences for human health. Such genomic gaffes, involving a single base in a length of DNA or RNA, are known as point mutations. They can result in mild abnormalities like color blindness as well as serious diseases, including neurofibromatosis, sickle-cell anemia, certain forms of cancer and Tay–Sachs...

New electrochemical platform paves the way for advanced portable diagnostic tools

November 25, 2019

Scientists at Arizona State University (ASU) and the University of Toronto (U of T) and have developed the first direct gene circuit to electrode interface by combining cell-free synthetic biology with state-of-the-art nanostructured electrodes. Long inspired by concepts from the field of electronics, with its circuits and logic gates, synthetic biologists have sought to reprogram biological systems to carry out artificial functions for medical, environmental, and pharmaceutical applications....

That’s a switch! Synthetic circuits regulate gene expression

November 4, 2019

During the first flickering of life on earth, ribonucleic acid (RNA) occupied center stage. Since its shadowy beginnings, RNA has become a basic constituent of all living cells, faithfully transcribing DNA messages contained in genes and translating these into proteins. Now, Alex Green and his group at ASU’s Biodesign Institute and scientists from the Wyss Institute for Biologically Inspired Engineering and Northwestern University, along with a group of...

Two ASU professors receive 2018 NIH New Innovator Award

October 2, 2018

“No. 1 in innovation” is an accolade ASU proclaims proudly in all realms of university life. Today, ASU proved once again that it is deserving of such a title.      ASU professors, Nicholas Stephanopoulos, assistant professor in the School of Molecular Sciences, and Rizal Hariadi, assistant professor in the Department of Physics, both researchers in the Biodesign Center for Molecular Design and Biomimetics, were announced as the recipients of the 2018 NIH New Innovator...

Alex Green wins $2.1M NIH New Innovator Award

October 10, 2017

The National Institutes of Health (NIH) has awarded a five-year, $2.1 million grant to ASU Biodesign Institute professor and School of Molecular Sciences faculty member Alexander Green to pursue innovative approaches to major contemporary challenges in biomedical research. The highly competitive grants, which were recently announced Oct. 5, were among 86 such awards nationwide, were made under the High-Risk, High-Reward Research program supported by the NIH Common Fund. “I...

Living computers: RNA circuits transform cells into nanodevices

July 26, 2017

The interdisciplinary nexus of biology and engineering, known as synthetic biology, is growing at a rapid pace, opening new vistas that could scarcely be imagined a short time ago. In new research, Alex Green, a professor at ASU's Biodesign Institute, demonstrates how living cells can be induced to carry out computations in the manner of tiny robots or computers. The results of the new study have significant implications for intelligent drug design and smart drug delivery, green energy...

Alex Green honored for early career achievements

March 22, 2017

Honored for Zika virus work and New Investigator Award to develop valley fever test kit ASU assistant professor of the School of Molecular Sciences and Biodesign Institute researcher Alex Green earned double accolades this year, for outstanding research in molecular science. The most recent award, which comes from the Arizona Biomedical Research Commission (ABRC), will fund Green’s research on an easy to use test kit for Valley fever, which is a disease caused by fungal spores native to...

Junior faculty in ASU's School of Molecular Sciences receive recognition

March 15, 2017

Four faculty members in the School of Molecular Sciences have recently received national recognition for their research and scholarship. Assistant Professors Ryan Trovitch and Gary Moore were awarded prestigious National Science Foundation CAREER awards. These awards are designed to support teacher-scholars who most effectively integrate research and education within the context of the mission of their organization, and are the most competitive of the National Science Foundations...

Zika test among ASU research highlights for 2016

January 3, 2017

A roundup of some of the university’s top stories of 2016 It was a year of big headlines for both the nation and Arizona State University. As the world has been faced with new challenges — and opportunities for new solutions — ASU has found innovative ways to help the communities it serves. The university’s faculty, staff and students have made advancements in health, space exploration, robotics and more, all while expanding access to education and extending compassion to...

Popular Science lists Zika test among its Best of What’s New in 2016

October 20, 2016

Developed by ASU and Harvard researchers, test is low-cost and could revolutionize field testing Popular Science named a low-cost Zika virus test developed by researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University in Boston and Arizona State University a 2016 Best of What’s New award winner in the health category. “We’re really honored to have our work recognized by Popular Science,” Green said. “It’s been exciting to see the...