Biodesign Center for Applied Structural Discovery

Uncovering protein structure and function

Proteins in plants and animals carry out tasks critical for survival, including metabolism and tissue repair, immunological responses, and capturing and using energy from sunlight to produce the oxygen we breathe and the food we eat. Recognizing how proteins accomplish this requires an understanding of their structure, dynamics, and physical and chemical processes at the molecular and atomic scales.

The Biodesign Center for Applied Structural Discovery brings together researchers from diverse disciplines to develop groundbreaking technologies and methods to accelerate discoveries involving the structure and functions of biomolecules, especially proteins. Breakthrough knowledge will spark innovations that improve human health and provide clean energy and food for future generations.

 

Director

Petra Fromme

 

Petra Fromme is an internationally leader in photosynthesis, protein macromolecular crystallography using synchrotrons and protein nanocrystallography using X-ray Free Electron Lasers. She has vast experience unravelling the structure and function of Photosystem I and II proteins and ATP synthase. Specifically, she studies the structure-to-function relationship of membrane proteins involved in bioenergy conversion and infectious diseases. Fromme contributed to the development of serial femtosecond nanocrystallography for analyzing proteins using high-intensity XFEL.

Faculty

Po-Lin Chiu

Assistant Professor

Petra Fromme

Director

Raimund Fromme

Associate Research Professor

William Graves

Associate Professor

Debbie Hansen

Associate Research Professor

Brenda Hogue

Professor

Richard Kirian

Assistant Professor

Wei Liu

Assistant Professor

Yuval Mazor

Assistant Professor

Gary Moore

Assistant Professor

Brent Nannenga

Assistant Professor

Alexandra Ros

Associate Professor

Scott Sayres

Assistant Professor

Abhishek Singharoy

Assistant Professor

John Spence

Regents' Professor

Uwe Weierstall

Research Professor

 

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