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Biodesign Directory Profile

Contact Information

(480)727-9061

Jeffrey LaBelle, PhD, MS

Courtesy Affiliate

The Biodesign Institute, Biodesign Administration

Bio

 

Jeffrey T La Belle is currently an Assistant Research Professor in the School of Biological Health and Systems Engineering and the Biodesign Institute at Arizona State University.  He has a Ph.D. and Masters in Bioengineering from ASU and a MS and BS in Electrical Engineering from Western New England College in Springfield Massachusetts.  The lab includes students from bioengineering, electrical engineering, mechanical engineering, chemical engineering, computer science engineering, as well as biology and chemistry programs at ASU.  Our research focus revolves around label-free, noninvasive sensing and point-of-care technologies.

In the La Belle Group, we are currently developing electrochemical sensors for noninvasive glucose sensing, the novelty of our design is to obtain tear fluid for tear to blood glucose correlation in a noninvasive means to increase patient compliance.  The next leap in technology for diabetes care is a multiplexed sensor that will add more depth of information for a self-monitoring blood glucose devices, here five accepted markers for DM care and management, including glucose, HbA1c, among others are simultaneously monitored on a single strip sensor.  This technology we are developing could also allow for continuous and single use stress sensing technologies.  Other applications of the sensing technologies include small molecule, DNA, protein, and whole cell detection to address changing climate in point-of-care technologies and medicine.  On the activation side of our research, we are fabricating nitinol staggered muscle arrays that mimic skeletal muscle and we have recently demonstrated over 30% compression in our SMA’s similar to muscle bundles. Our approach to design is simple, look at what the user needs and/or wants and apply a unique solution.  We have bioengineering, chemical, electrical, mechanical engineers in the group as well as biology and chemistry, a well diversified group to tackle the challenges in health care today.

Selected Publications

2007

  • La Belle, Jeffrey T, Gerlach, Jared Q, Svarovsky, Sergei, Joshi, Lokesh. Label-Free Impedimetric Detection of Glycan-Lectin Interactions. Analytical Chemistry (2007).

2006

  • Dai, Z, Kawde, A #NAME?, Xiang, Y, La Belle, Jeffrey T, Gerlach, J Q, Bhavanandan, V P, Joshi, L, Wang, J. Nanoparticle-Based Bioelectronic Sensing of Glycan-Lectin Interactions. JACS (2006).
  • Tangkuaram, Tanin, Gerlach, Jared Q, Xiang, Yun, Kawde, Abdel-Nasser, Dai, Zong, Bhavanandan, Veer P, La Belle, Jeffrey T, Veerasai, Waret, Joshi, Lokesh, Wang, Joseph. Sensitive and rapid electrochemical bioassay of glycosidase activity. The Analyst (2006).

2003

  • Montaño, G A, Bowen, B P, La Belle, Jeffrey T, Woodbury, N W, Pizziconi, V B, Blankenship, R E. Characterization of Chlorobium tepidum chlorosomes. A calculation of bacteriochlorophyll c per chlorosome and oligomer modeling. Biophys (2003).

2001

  • Montaño, GA, La Belle, Jeffrey T, Woodbury, N W, Pizziconi, V B, Blankenship, R E, Bowen, J T. Determination of the number of bacteriochlorophyll molecules per chlorosome light-harvesting complex in Chlorobium tepidum. PS 2001, 12th International Congress of Photosynthesis (2001).