Svarovsky

Svarovsky Lab: Publications

1. Svarovsky, S.A.*, Joshi, L., ”Biocombinatorial Selection of Carbohydrate Binding Agents of Therapeutic Significance”, Current Drug Discovery Technology, 2008, 5(1), 20-28.

2. La Belle, J.T.; Gerlach, J.; Svarovsky, S.,* Joshi, L.* ”Rapid Label-Free Impedimetric Detection of Glycan-Lectin Interactions”, Analytical Chemistry, 2007, 79, 6959-6964.

3. Wang, J., Dai, Z., Kawde, A., Xiang, Y., La Belle, J., Gerlach, J., Bhavandan, V., Svarovsky, S., Joshi, L., “Nanocrystal-based electrochemical biosensors of glycan-lectin interactions suitable for point-of-care use” Nanomedicine: Nanotechnology, Biology and Medicine, Volume 2, Issue 4, 314.

4. Svarovsky, S.A.; Barchi, J. Jr., Chapter 20, “De Novo Synthesis of Biofunctional Carbohydrate-Encapsulated Quantum Dots” ACS Symposium Series (2007), 960 (Frontiers in Modern Carbohydrate Chemistry), 357-392.

5. Svarovsky, S.A., Szekly, Z., Barchi, J.J.* “Synthesis of Gold Nanoparticles Bearing the Thomsen-Friedenreich Disaccharide: A New Multivalent Presentation of an Important Tumor Antigen” Tetrahedron Asymmetry (Special Edition), 2005, 16(2), 587-598.

6. Svarovsky, S. A.*, Taraban, M. B., Barchi, J. J. “Facile Photochemical Synthesis of Mixed Siloxyacetal Glycosides as Potential pH-Sensitized Prodrugs for Selective Treatment of Solid Tumors” Organic and Biomolecular Chemistry, 2004, 2(21), 3155-3161.

7. Svarovsky, S.A., Borovkov, A.,* Sykes, K., Cationic Gold Microcarriers for Ballistic Delivery of Nucleic Acids, BioTechniques, 2008, 45(5), 535-540.

8. Morales Betanzos, C., Gonzalez-Moa, M., Johnston, S.A., Svarovsky, S.A.* “Facile Labeling of Lipoglycans with Quantum Dots”, Biochemical & Biophysical Research Communications, 2009, 380(1), 1-4.

9. Boltz, K.W., Gonzalez-Moa, M., Stafford, P., Johnston, S.A., Svarovsky, S.A.* “Peptide Microarrays for Carbohydrate Recognition”, Analyst, 2009, DOI: 10.1039/b823156g.

10. Morales Betanzos, C., Gonzalez-Moa, M.J., Boltz, K.W., Vander Werf, B., Johnston, S.A., Svarovsky, S.A.* “Bacterial Glycoprofiling by Using Random Sequence Peptide Microarrays”, ChemBioChem, 2009, DOI: 10.1002/cbic.200800716.

Selected U.S. Patents

1. Svarovsky, S.A.; Barchi, J.J., Jr. “Carbohydrate-encapsulated quantum dots for biological imaging” PCT Int. Appl. (2005), 115 pp. WO 2005093422.

2. Barchi, J.J., Jr.; Svarovsky, S.A. “Bio-functionalized quantum dots for biological imaging using disaccharides” PCT Int. Appl. (2005), 53 pp. WO 2005053649.

3. Barchi, J.J., Jr.; Rittenhouse-Olson, K.; Svarovsky, S. “Carbohydrate antigen-nanoparticle conjugates and uses thereof as antimetastatic agents in treating cancer” PCT Int. Appl. (2005), 71 pp. WO 2005046722.

4. Magnani, J.M.; Sarkar, A.; Patton, J.P.; Svarovsky, S.A.; Beat, E., “Preparation of hetero-bifunctional pseudo-oligosaccharides as pan-selectin inhibitors and anti-inflammatory agents, PCT Int. Appl. (2007), 94pp, WO2007028050.

5. Svarovsky, S.A., Borovkov, A., Sykes, K., Charged Hard Core Microparticles and Uses thereof. Provisional PCT application filed Nov 8th, 2007.

6. Sheleg, S., Hixon, H., Svarovsky, S., Cohen, B., “Long-Term Hypothermic Preservation of Biological Tissues and Cells”, National US application filed May 12, 2008.

7. Svarovsky, S.A., Boltz, K.W., Johnston, S.A., “Artificial Lectin Mimics and Uses Thereof”, International PCT application filed Oct 31, 2008.

Latest Presentations

1. “Lectinomimetics as New Antimicrobial Leads” Sergei A. Svarovsky, International Conference on Chemistry and Biology of Sialic Acids, Sialoglyco2008, Moscow-St. Petersburg, Russia, July 21-26, 2008.

2. “Gold Glycopeptide nanoparticles: an Update” J. Barchi, Sundgren, A., K. Rittenhouse-Olsen, and S. Svarovsky, NIH Glycosciences Research Day, Bethesda, MD, May 9, 2008.

3. “Progress towards Development of Template-Assembled Synthetic Lectins”, Gonzalez-Moa, M.J., Svarovsky, S.A.*, 41st Western Regional ACS Meeting, Frontiers in Chemistry, Biopharmaceuticals & Biotechnology, October 9-13, 2007.

4. “Immunosorbing Glyconanosponges for Cardiac Tissue Engineering” Svarovsky, S.A., XIXth International Symposium on Glycoconjugates, 15-20 July, 2007, Cairns, Australia.

5. “Tumor-Associated Carbohydrate Antigen-Coated Nanoparticles: Synthesis, in vitro and in vivo Characterization” Joseph J. Barchi, Kate Rittenhouse-Olson, Jamie Heimburg, Sergei Svarovsky, Anil Patri, Jiwen Zheng and Andreas Sundgren, Materials Research Society Symposium, San Francisco, CA, April 10-13, 2007.