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The Center manages a large number of grants.  Bertram Jacobs has a $5.5 million, five-year grant from the National Institutes of Health's Biodefense Partnership program to develop and test a modified smallpox vaccine; Josephine Clark-Curtiss has just received a $1.7 million NIH grant to study M. tuberculosis pathogenesis; Roy Curtiss has eight grant projects funded by the Grand Challenges in Global Health Initiative, NIH, USDA and the Ellison Medical Foundation and Brenda Hogue has two NIH-funded projects.  Several teams are creating and evaluating methods of preventing HIV/AIDS and other sexually-transmitted diseases. Charles Arntzen directs a Collaborative Research Center established with a $7.4 million grant from the NIH to develop a microbicide to prevent HIV infection, while Tsafrir Mor received $670 thousand from NIH for a plant-based vaccine against HIV. Qiang "Shawn" Chen has recently been awarded a $1.5 million grant from the National Institutes of Health to develop mAb-based therapuetics for West Nile virus infections.

List of Grant Titles

• Salmonella Anti-Influenza DNA and Antigen Delivery Vaccine, National Institutes of Health
• Rapid & Large-Scale Plant-based Production of Catalytic Nerve-Agent Bioscavengers, Army Medical Research & NIH
• Evaluation of host-pathogen interaction during exposure to microgravity analogues, NASA-Ames Research Center Improving the immunogenicity of poxvirus based vectors, Center Hospitalier Universitaire Vaudois
• Microbe - Inflight Project, NASA-Ames Research Center
• PDVI Project, Pediatric Dengue Vaccine Initiative
• Mechanism of Vaccinia-Specific Cell Homing, National Institute of Allergy & Infectious Diseases
• Mechanism of Vaccinia-Specific Cell Homing, National Institute of Allergy & Infectious Diseases
• A Live Recombinant Attenuated Salmonella Anti-Pneumococcal Vaccine for Newborns, Gates (Bill and Melinda) Foundation
• Generation of Transgenic Plants that Express Capsid Proteins of Norwalk-like Viruses, Boyce Thompson Institute for Plant Research
• Development of a Vaccine for Ebola Virus in Plant System, National Institute of Allergy & Infectious Diseases
• Gene Expression in Mycobacterium Tuberculosis, National Institute of Allergy & Infectious Diseases
• Attenuated Salmonella Antigen and DNA Vaccine Delivery Vaccines Against Eimeria, U.S. Department of Agriculture
• Providing an Economic Benefit to Using a Vaccine to Enhance Food Safety and Reduce Antibiotic Use in Agriculture, The Ellison Medical Foundation
• Recombinant Attenuated Salmonella Vaccines for Humans, National Institute of Allergy & Infectious Diseases
• Attenuated Live and Recombinant Yersinia Pestis Vaccines, National Institute of Allergy & Infectious Diseases
• Molecular Genetic Analysis of Salmonella Pathogenicity, National Institute of Allergy & Infectious Diseases
• Recombinant Attenuated Salmonella Vaccines for Humans, National Institute of Allergy & Infectious Diseases
• S. Typhimurium Vaccine Against Bacterial Enteropathogens, National Institute of Allergy & Infectious Diseases
• Joint University Project #1638, Combinatorial Antibody Libraries of Orthopoxviruses, U.S. Department of Defense
• MIHR Projects, Centre for Mngmnt. of IP in Health Res. and Development
• Arizona State University PREP for Biomedical Research - Year 2, National Institutes of Health
• Plant-Made Microbicides and Mucosal Vaccines for STIs, National Institute of Allergy & Infectious Diseases
• Development of a safer smallpox vaccine, National Institutes of Health
• Molecular Analysis of Coronavirus Assembly, Continuation of LMS0024, National Institute of Allergy & Infectious Diseases
• Plant Expressed Antigens of Shiga Toxin-producing E. Coli, National Institute of Allergy & Infectious Diseases
• Role of the E3L Gene in Poxvirus Pathogenesis, National Institute of Allergy & Infectious Diseases
• Hepatitis B. Subunit Oral Vaccine in Transgenic Plants, National Institutes of Health
• Plant Production of Vaccines and Therapeutic Antibodies for Strategic Protection Against Biowarefare Pathogens, DOD-Army Research Office
• Pathogenic Mechanisms in Poxviruses, Dana (Charles A.) Foundation

 

The active collaborations on funded grants include:

• University of Maryland ’s Center for Vaccine Development
• St. George's Hospital’s Dept. of Infectious Diseases (London, England)
• The Council for Scientific and Industrial Research in Pretoria (S. Africa)
• Mapp Biopharmaceuticals, Inc. (San Diego)
• Baylor College of Medicine’s Virology Department  (Houston, TX)
• University of Rochester’s Infectious Disease Unit  (New York)
• Roswell Park Cancer Institute’s Department of Molecular Immunology (Buffalo, NY)
• National Institute of Infectious Diseases’ Department of Virology II (Tokyo, Japan)
• University of Alabama at Birmingham (Birmingham, AL)
• Tufts University (Boston, massachusetts)
• International Vaccine Institute (Seoul, Korea)
• Saint Louis University
• University of Adelaide (South Australia)
• Pusan National University, (Pusan Republic of Korea)
• Duke University, (North Carolina)
• University of Melbourne (Melbourne, Australia)
• University of Kentucky (Lexington, Kentucky)
• Washington University (St. Louis, Missouri)