Biodesign News

Cardineau chosen as Centennial Professor


Biodesign's Nickerson Speaks on Capitol Hill


Mayo Clinic, Biodesign Institute collaboration examines link between gut bacteria and obesity


Overview

Since its inception in 2002, scientists in the Center for Evolutionary Functional Genomics (EFG) have leveraged innovations in information technology into tools for testing long-standing biological problems. The recent ability to obtain the complete DNA sequence information of any organism, or genome, has allowed us to map and explore the genetic blueprints necessary for life as well as their evolution. We are developing new methods for exploring the gene interactions that guide the maturation of a single fertilized egg cell into a complex adult animal with trillions of cells and building easy-to-use computer software for the analysis of genomic databases. Using developmental gene expression image data from Drosophila, we are developing the first-of-a-kind computational tool and web resource for the digital analysis of developmental gene expression patterns. Read More »

Center News

Big Buzz: Landmark fruit fly DNA study advances genetics

In a set of papers published in the journal Nature, the Biodesign Institute’s Sudhir Kumar, along with colleagues Alan Filipski, Sonja Prohaska and Stuart Newfeld, participated in the largest comparative DNA analysis of higher organisms ever assembled. In all, the complete DNA sequences, or genomes, from a dozen different fruit fly species were assembled to understand the differences between species at the DNA level. Read More »

The Aye-Ayes Have it: The preservation of color vision in a creature of the night

A quest to gain a more complete picture of color vision evolution has led Biodesign Institute researcher Brian Verrelli to an up-close, genetic encounter with one of the world’s most rare and bizarre-looking primates. Read More »

“The EFG is building a leading research program at the interface of genomics and bioinformatics that emphasizes the development of methods, technologies, and tools for analyzing genome sequence and functional genomics data. Using novel comparative genomics and gene expression approaches, we are formulating biological hypotheses and addressing them using large-scale datasets.”

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